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Displaying toxins 51 - 75 of 3678 in total
T3DB ID Name
CAS Number
Formula
Weight
StructureTypeMechanism of Toxicity
T3D0058m-Xylene
108-38-3
C8H10
106.165 g/mol
Thumb
  • Aromatic Hydrocarbon
  • Food Toxin
  • Industrial/Workplace Toxin
  • Lachrymator
  • Metabolite
  • Natural Compound
  • Organic Compound
  • Pollutant
  • Solvent
m-Xylene is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholinestera...more
Number of Targets: 5
T3D0059cis-Chlordane
5103-71-9
C10H6Cl8
409.779 g/mol
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  • Organic Compound
  • Organochloride
  • Pesticide
  • Synthetic Compound
Chlordane is believed to bind irreversibly to DNA, leading to cell death or altered cellular function. It also affects transcription by antagonizing estrogen-related r...more
Number of Targets: 14
T3D0061Methoxychlor
72-43-5
C16H15Cl3O2
345.648 g/mol
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  • Aromatic Hydrocarbon
  • Ether
  • Household Toxin
  • Organic Compound
  • Organochloride
  • Pesticide
  • Pollutant
  • Synthetic Compound
Certain mono- and bis-hydroxy metabolites of methoxychlor, especially 2,2-bis(p-hydroxyphenyl)-1,1, 1-trichloroethane (HPTE), act as estrogen analogues. HPTE is an est...more
Number of Targets: 51
T3D0062Benzo[k]fluoranthene
207-08-9
C20H12
252.309 g/mol
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  • Aromatic Hydrocarbon
  • Cigarette Toxin
  • Food Toxin
  • Industrial By-product/Pollutant
  • Industrial/Workplace Toxin
  • Natural Compound
  • Organic Compound
  • Pollutant
  • Polycyclic Aromatic Hydrocarbon
The ability of PAH's to bind to blood proteins such as albumin allows them to be transported throughout the body. Many PAH's induce the expression of cytochrome P450 e...more
Number of Targets: 3
T3D0063Endrin ketone
53494-70-5
C12H8Cl6O
380.909 g/mol
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  • Ketone
  • Organic Compound
  • Organochloride
  • Pesticide
  • Synthetic Compound
Endrin antagonizes the action of the neurotransmitter gamma-aminobutyric acid (GABA) acting at the GABA-A receptors, effectively blocking the GABA-induced uptake of ch...more
Number of Targets: 38
T3D0064trans-Chlordane
5103-74-2
C10H6Cl8
409.779 g/mol
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  • Organic Compound
  • Organochloride
  • Pesticide
  • Synthetic Compound
Chlordane is believed to bind irreversibly to DNA, leading to cell death or altered cellular function. It also affects transcription by antagonizing estrogen-related r...more
Number of Targets: 14
T3D0065Chromium(VI) oxide
1333-82-0
CrO3
99.994 g/mol
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  • Chromium Compound
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Pollutant
  • Synthetic Compound
Hexavalent chromium's carcinogenic effects are caused by its metabolites, pentavalent and trivalent chromium. The DNA damage may be caused by hydroxyl radicals produce...more
Number of Targets: 5
T3D0066Methane
74-82-8
CH4
16.043 g/mol
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  • Food Toxin
  • Fuel
  • Industrial Precursor/Intermediate
  • Industrial/Workplace Toxin
  • Metabolite
  • Natural Compound
  • Organic Compound
Methane is an asphyxiant and displaces oxygen in enclosed spaces. At high enough concentrations, oxygen depletion may cause asphyxiation. Low concentrations of surroun...more
Number of Targets: 0
T3D0067beta Endosulfan
33213-65-9
C9H6Cl6O3S
406.925 g/mol
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  • Ester
  • Food Toxin
  • Organic Compound
  • Organochloride
  • Pesticide
  • Pollutant
  • Synthetic Compound
Endosulfan antagonizes the action of the neurotransmitter gamma-aminobutyric acid (GABA) acting at the GABA-A receptors, effectively blocking the GABA-induced uptake o...more
Number of Targets: 49
T3D0069Endrin aldehyde
7421-93-4
C12H8Cl6O
380.909 g/mol
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  • Aldehyde
  • Organic Compound
  • Organochloride
  • Pesticide
  • Pollutant
  • Synthetic Compound
Endrin antagonizes the action of the neurotransmitter gamma-aminobutyric acid (GABA) acting at the GABA-A receptors, effectively blocking the GABA-induced uptake of ch...more
Number of Targets: 38
T3D0070Benzofluoranthene
56832-73-6
C20H12
252.309 g/mol
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  • Aromatic Hydrocarbon
  • Food Toxin
  • Industrial By-product/Pollutant
  • Industrial/Workplace Toxin
  • Natural Compound
  • Organic Compound
  • Pollutant
  • Polycyclic Aromatic Hydrocarbon
The ability of PAH's to bind to blood proteins such as albumin allows them to be transported throughout the body. Many PAH's induce the expression of cytochrome P450 e...more
Number of Targets: 3
T3D0071Toluene
108-88-3
C7H8
92.138 g/mol
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  • Aromatic Hydrocarbon
  • Cosmetic Toxin
  • Food Toxin
  • Household Toxin
  • Industrial Precursor/Intermediate
  • Industrial/Workplace Toxin
  • Metabolite
  • Natural Compound
  • Organic Compound
  • Pollutant
  • Solvent
Toluene is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholinesteras...more
Number of Targets: 39
T3D00722-Oxohexane
591-78-6
C6H12O
100.159 g/mol
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  • Food Toxin
  • Industrial/Workplace Toxin
  • Ketone
  • Metabolite
  • Natural Compound
  • Organic Compound
  • Solvent
2-Hexanone's toxicity is believed to be caused by covalent binding of its metabolites, especially 2,5-hexanedione, with axonal components of nerve tissue and inhibitio...more
Number of Targets: 16
T3D00732,3,7,8-Tetrachlorodibenzo-p-dioxin
1746-01-6
C12H4Cl4O2
321.971 g/mol
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  • Aromatic Hydrocarbon
  • Chlorinated Dibenzo-p-dioxin
  • Ether
  • Industrial By-product/Pollutant
  • Industrial/Workplace Toxin
  • Organic Compound
  • Organochloride
  • Pollutant
  • Synthetic Compound
CDDs bind to the aryl hydrocarbon (Ah) receptor and subsequently alter the transcription of several genes (oncogenes, growth factors, receptors, hormones, and drug-met...more
Number of Targets: 2
T3D0074Zinc
7440-66-6
Zn
65.408 g/mol
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  • Drug
  • Food Toxin
  • Household Toxin
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Metabolite
  • Metal
  • Natural Compound
  • Pollutant
  • Trace Element
  • Zinc Compound
Excessive zinc intake alters copper and iron absorption, most likely through competitive binding in intestinal mucosal cells. Stomach acid dissolves metallic zinc, pro...more
Number of Targets: 28
T3D0075Dimethylarsinate
15132-04-4
C2H7AsO2
137.997 g/mol
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  • Arsenic Compound
  • Food Toxin
  • Household Toxin
  • Industrial/Workplace Toxin
  • Metabolite
  • Organic Compound
  • Organometallic
  • Pesticide
  • Synthetic Compound
Arsenic and its metabolites disrupt ATP production through different mechanisms. At the level of the citric acid cycle, arsenic inhibits the pyruvate dehydrogenase and...more
Number of Targets: 54
T3D0076Di(2-ethylhexyl)phthalate
117-81-7
C24H38O4
390.556 g/mol
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  • Aromatic Hydrocarbon
  • Cosmetic Toxin
  • Ester
  • Ether
  • Food Toxin
  • Household Toxin
  • Industrial/Workplace Toxin
  • Organic Compound
  • Phthalate
  • Plasticizer
  • Pollutant
  • Synthetic Compound
Monoethylhexylphthalate (MEHP), one of the major metabolites of DEHP, induces peroxisome proliferation by activating peroxisome proliferator activated receptors. This ...more
Number of Targets: 17
T3D0077Chromium
7440-47-3
Cr
51.993 g/mol
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  • Chromium Compound
  • Cigarette Toxin
  • Food Toxin
  • Household Toxin
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Metabolite
  • Metal
  • Natural Compound
  • Pollutant
Hexavalent chromium's carcinogenic effects are caused by its metabolites, pentavalent and trivalent chromium. The DNA damage may be caused by hydroxyl radicals produce...more
Number of Targets: 6
T3D0078Naphthalene
91-20-3
C10H8
128.171 g/mol
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  • Aromatic Hydrocarbon
  • Food Toxin
  • Household Toxin
  • Industrial By-product/Pollutant
  • Industrial/Workplace Toxin
  • Metabolite
  • Natural Compound
  • Organic Compound
  • Pollutant
  • Polycyclic Aromatic Hydrocarbon
PAH's such as naphthalene are transported throughout the body after binding blood proteins such as albumin. Binding to the aryl hydrocarbon receptor or glycine N-methy...more
Number of Targets: 12
T3D00791,1-Dichloroethene
75-35-4
C2H2Cl2
96.943 g/mol
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  • Industrial/Workplace Toxin
  • Lachrymator
  • Organic Compound
  • Organochloride
  • Pollutant
  • Synthetic Compound
1,1-Dichloroethene toxicity is caused by its reactive metabolites, which include epoxides, acyl chlorides, and halogenated aldehydes generated via oxidation by cytochr...more
Number of Targets: 39
T3D0080Dichloromethane
1975-09-02
CH2Cl2
84.933 g/mol
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  • Food Toxin
  • Household Toxin
  • Industrial/Workplace Toxin
  • Metabolite
  • Organic Compound
  • Organochloride
  • Pesticide
  • Pollutant
  • Solvent
  • Synthetic Compound
Methylene chloride targets the lungs, blood system, and nervous system. In the lungs its metabolites damage Clara cells. It is also metabolized into carbon monoxide, w...more
Number of Targets: 11
T3D00822,4,6-Trinitrotoluene
118-96-7
C7H5N3O6
227.131 g/mol
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  • Aromatic Hydrocarbon
  • Explosive Agent
  • Food Toxin
  • Indicator and Reagent
  • Industrial/Workplace Toxin
  • Nitrite
  • Organic Compound
  • Synthetic Compound
2,4,6-Trinitrotoluene is a competitive inhibitor with respect to NADPH and a noncompetitive inhibitor with respect to L-arginine. It binds to the P450 reductase domain...more
Number of Targets: 1
T3D0084Hydrazine
302-01-2
H4N2
32.045 g/mol
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  • Cigarette Toxin
  • Food Toxin
  • Hydrazine
  • Industrial Precursor/Intermediate
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Metabolite
  • Non-Metal
  • Organic Compound
  • Pollutant
  • Synthetic Compound
At least two mechanisms of action have been observed. One involves the direct binding of those hydrazines with a free amino group (hydrazine and 1,1-dimethylhydrazine)...more
Number of Targets: 0
T3D00851,2-Dichloroethane
107-06-2
C2H4Cl2
98.959 g/mol
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  • Food Toxin
  • Industrial Precursor/Intermediate
  • Industrial/Workplace Toxin
  • Metabolite
  • Organic Compound
  • Organochloride
  • Pollutant
  • Solvent
  • Synthetic Compound
1,2-Dichloroethane is metabolized to 2-chloroacetaldehyde, S-(2-chloroethyl)glutathione by conjugation with glutathione, and to other putative reactive intermediates c...more
Number of Targets: 39
T3D00862,4,6-Trichlorophenol
88-06-2
C6H3Cl3O
197.446 g/mol
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  • Aromatic Hydrocarbon
  • Organic Compound
  • Organochloride
  • Pesticide
  • Pollutant
  • Synthetic Compound
2,4,6-Trichlorophenol is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acety...more
Number of Targets: 40
Displaying toxins 51 - 75 of 3678 in total