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Displaying toxins 101 - 125 of 3678 in total
T3DB ID Name
CAS Number
Formula
Weight
StructureTypeMechanism of Toxicity
T3D0115alpha-Hexachlorocyclohexane
319-84-6
C6H6Cl6
290.830 g/mol
Thumb
  • Organic Compound
  • Organochloride
  • Pesticide
  • Pollutant
  • Synthetic Compound
Hexachlorocyclohexane is a neurotoxin that interferes with GABA neurotransmitter function by interacting with the GABA-A receptor-chloride channel complex at the picro...more
Number of Targets: 42
T3D01161,2,3-Trichlorobenzene
87-61-6
C6H3Cl3
181.447 g/mol
Thumb
  • Aromatic Hydrocarbon
  • Industrial/Workplace Toxin
  • Lachrymator
  • Organic Compound
  • Organochloride
  • Pesticide
  • Solvent
  • Synthetic Compound
Trichlorobenzene may uncouple mitochondrial oxidative phosphorylation, inducing potassium ion release and inhibiting respiratory control. It's metabolites may covalent...more
Number of Targets: 42
T3D0117Manganese
7439-96-5
Mn
54.937 g/mol
Thumb
  • Cosmetic Toxin
  • Food Toxin
  • Household Toxin
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Manganese Compound
  • Metabolite
  • Metal
  • Natural Compound
  • Pollutant
Manganese is a cellular toxicant that can impair transport systems, enzyme activities, and receptor functions. It primarily targets the central nervous system, particu...more
Number of Targets: 10
T3D0119Chrysotile asbestos
12001-29-5
Mg3Si2O5(OH)4
Not Available
T3d0119
  • Household Toxin
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Mineral
  • Natural Compound
  • Pollutant
When asbestos fibers are inhaled, many are deposited on the epithelial surface of the respiratory tree. Fibers that are retained in the lung or mesothelium for long pe...more
Number of Targets: 1
T3D0120Strontium-90
10098-97-2
Sr
89.908 g/mol
Thumb
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Metal
  • Natural Compound
  • Pollutant
  • Radioactive
  • Radioactive Isotope
  • Strontium Compound
The fact that strontium is chemically similar to calcium allows it to exchange for calcium in bone. It affects bone development and strength by binding directly to hyd...more
Number of Targets: 1
T3D0121Plutonium-239
15117-48-3
Pu
239.052 g/mol
Thumb
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Metal
  • Natural Compound
  • Plutonium Compound
  • Pollutant
  • Radioactive
  • Radioactive Isotope
The alpha radiation plutonium emits does not penetrate the skin but can irradiate internal organs when plutonium is inhaled or ingested. Particularly at risk are the s...more
Number of Targets: 1
T3D0122Polonium-210
13981-52-7
Po
209.983 g/mol
Thumb
  • Cigarette Toxin
  • Inorganic Compound
  • Metal
  • Metalloid
  • Natural Compound
  • Plutonium Compound
  • Pollutant
  • Radioactive
  • Radioactive Isotope
The alpha radiation polonium emits does not penetrate the skin but can irradiate internal organs when polonium is inhaled or ingested. The ionizing radiation produced ...more
Number of Targets: 1
T3D0123Methylmercury
22967-92-6
CH3Hg
215.620 g/mol
Thumb
  • Mercury Compound
  • Organic Compound
  • Organometallic
  • Pollutant
  • Synthetic Compound
  • Waste Product
Methylmercury is neurotoxic. It potently affects the release of neurotransmitter from presynaptic nerve terminals. Methylmercury alters calcium ion concentrations by a...more
Number of Targets: 70
T3D0124Plutonium-238
13981-16-3
Pu
238.050 g/mol
Thumb
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Metal
  • Natural Compound
  • Plutonium Compound
  • Pollutant
  • Radioactive
  • Radioactive Isotope
The alpha radiation plutonium emits does not penetrate the skin but can irradiate internal organs when plutonium is inhaled or ingested. Particularly at risk are the s...more
Number of Targets: 1
T3D0125Lead-210
14255-04-0
Pb
209.984 g/mol
Thumb
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Lead Compound
  • Metal
  • Natural Compound
  • Pollutant
  • Radioactive
  • Radioactive Isotope
Lead mimics other biologically important metals, such as zinc, calcium, and iron, competing as cofactors for many of their respective enzymatic reactions. For example,...more
Number of Targets: 30
T3D0126Plutonium
7440-07-5
Pu
244.000 g/mol
Thumb
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Metal
  • Natural Compound
  • Plutonium Compound
  • Pollutant
  • Radioactive
The alpha radiation plutonium emits does not penetrate the skin but can irradiate internal organs when plutonium is inhaled or ingested. Particularly at risk are the s...more
Number of Targets: 1
T3D0127Chlorpyrifos
2921-88-2
C9H11Cl3NO3PS
350.586 g/mol
Thumb
  • Aromatic Hydrocarbon
  • Household Toxin
  • Insecticide
  • Metabolite
  • Organic Compound
  • Organochloride
  • Organophosphate
  • Pesticide
  • Synthetic Compound
Chlorpyrifos is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholines...more
Number of Targets: 55
T3D0128Copper
7440-50-8
Cu
63.545 g/mol
Thumb
  • Copper Compound
  • Food Toxin
  • Household Toxin
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Metabolite
  • Metal
  • Natural Compound
  • Pollutant
Excess copper is sequestered within hepatocyte lysosomes, where it is complexed with metallothionein. Copper hepatotoxicity is believed to occur when the lysosomes bec...more
Number of Targets: 20
T3D0129Americium-241
86954-36-1
Am
241.057 g/mol
Thumb
  • Americium Compound
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Metal
  • Pollutant
  • Radioactive
  • Radioactive Isotope
  • Synthetic Compound
Americium toxicity results primarily from the damage done by the alpha particle emitted during radioactive decay. This alpha particle has very limited penetration in t...more
Number of Targets: 1
T3D0130Radon-220
22481-48-7
Rn
220.011 g/mol
Thumb
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Metal
  • Natural Compound
  • Non-Metal
  • Pollutant
  • Radioactive
  • Radioactive Isotope
  • Radium Compound
The ionizing radiation produced by radon causes cellular damage that includes DNA breakage, accurate or inaccurate repair, apoptosis, gene mutations, chromosomal chang...more
Number of Targets: 1
T3D0131Amosite asbestos
12172-73-5
(Na, K)0-1(Fe2+, Mg)2(Fe2+, Mg)5Si8O22(OH)2, approx. Fe2+5Mg2
Not Available
T3d0131
  • Amide
  • Amine
  • Ester
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Mineral
  • Natural Compound
  • Organic Compound
  • Pollutant
When asbestos fibers are inhaled, many are deposited on the epithelial surface of the respiratory tree. Fibers that are retained in the lung or mesothelium for long pe...more
Number of Targets: 1
T3D0132Iodine-131
10043-66-0
I
130.906 g/mol
Thumb
  • Halogen
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Natural Compound
  • Non-Metal
  • Pollutant
  • Radioactive
  • Radioactive Isotope
Iodide inhibits adenylate cyclase in thyroid gland follicle cells and decreases the TSH-induced rise in intracellular cAMP. This results in decreased iodination of thy...more
Number of Targets: 11
T3D0133Hydrogen cyanide
74-90-8
CHN
27.025 g/mol
Thumb
  • Cyanide Compound
  • Food Toxin
  • Industrial/Workplace Toxin
  • Metabolite
  • Natural Compound
  • Nitrile
  • Organic Compound
  • Pollutant
Organic nitriles decompose into cyanide ions both in vivo and in vitro. Consequently the primary mechanism of toxicity for organic nitriles is their production of toxi...more
Number of Targets: 44
T3D0134Tributyltin
688-73-3
C12H28Sn
291.060 g/mol
Thumb
  • Industrial/Workplace Toxin
  • Lachrymator
  • Organic Compound
  • Organometallic
  • Pesticide
  • Pollutant
  • Synthetic Compound
  • Tin Compound
Organotin compounds produce neurotoxic and immunotoxic effects. Organotins may directly activate glial cells contributing to neuronal cell degeneration by local releas...more
Number of Targets: 19
T3D0135Guthion
86-50-0
C10H12N3O3PS2
317.324 g/mol
Thumb
  • Ester
  • Food Toxin
  • Organic Compound
  • Organophosphate
  • Pesticide
  • Synthetic Compound
Guthion is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholinesteras...more
Number of Targets: 14
T3D0136Neptunium-237
13994-20-2
Np
237.048 g/mol
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  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Metal
  • Pollutant
  • Radioactive
  • Radioactive Isotope
  • Synthetic Compound
The ionizing radiation produced by neptunium causes cellular damage that includes DNA breakage, accurate or inaccurate repair, apoptosis, gene mutations, chromosomal c...more
Number of Targets: 1
T3D0137Chrysene
218-01-9
C18H12
228.288 g/mol
Thumb
  • Aromatic Hydrocarbon
  • Food Toxin
  • Industrial By-product/Pollutant
  • Industrial/Workplace Toxin
  • Natural Compound
  • Organic Compound
  • Pollutant
  • Polycyclic Aromatic Hydrocarbon
The ability of PAH's to bind to blood proteins such as albumin allows them to be transported throughout the body. Many PAH's induce the expression of cytochrome P450 e...more
Number of Targets: 5
T3D0138Chlordecone
143-50-0
C10Cl10O
490.636 g/mol
Thumb
  • Metabolite
  • Organic Compound
  • Organochloride
  • Pesticide
  • Pollutant
  • Synthetic Compound
It is believed that the α-noradrenergic and serotonergic transmitter systems in the central nervous system are the primary neurotransmitter systems affected by chlorde...more
Number of Targets: 55
T3D0139Iodine-129
15046-84-1
I
128.905 g/mol
Thumb
  • Halogen
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Natural Compound
  • Non-Metal
  • Pollutant
  • Radioactive Isotope
Iodide inhibits adenylate cyclase in thyroid gland follicle cells and decreases the TSH-induced rise in intracellular cAMP. This results in decreased iodination of thy...more
Number of Targets: 11
T3D0140Plutonium-240
14119-33-6
Pu
240.054 g/mol
Thumb
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Metal
  • Natural Compound
  • Plutonium Compound
  • Pollutant
  • Radioactive
  • Radioactive Isotope
The alpha radiation plutonium emits does not penetrate the skin but can irradiate internal organs when plutonium is inhaled or ingested. Particularly at risk are the s...more
Number of Targets: 1
Displaying toxins 101 - 125 of 3678 in total