Tmic
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Displaying toxins 126 - 150 of 3678 in total
T3DB ID Name
CAS Number
Formula
Weight
StructureTypeMechanism of Toxicity
T3D0141S,S,S-Tributyl phosphorotrithioate
78-48-8
C12H27OPS3
314.511 g/mol
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  • Organic Compound
  • Organophosphate
  • Pesticide
  • Synthetic Compound
S,S,S-Tributyl phosphorotrithioate is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the ac...more
Number of Targets: 17
T3D0142Bromine
7726-95-6
Br2
159.808 g/mol
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  • Food Toxin
  • Halogen
  • Inorganic Compound
  • Lachrymator
  • Metabolite
  • Natural Compound
  • Non-Metal
  • Pesticide
Bromine is a powerful oxidizing agent and is able to release oxygen free radicals from the water in mucous membranes. These free radicals are also potent oxidizers and...more
Number of Targets: 7
T3D0144Dicofol
115-32-2
C14H9Cl5O
370.486 g/mol
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  • Aromatic Hydrocarbon
  • Industrial/Workplace Toxin
  • Lachrymator
  • Organic Compound
  • Organochloride
  • Pesticide
  • Synthetic Compound
Like other organochloride pesticides, dicofol is believed to act by at least four mechanisms, possibly all functioning simultaneously. It may reduce potassium transpor...more
Number of Targets: 74
T3D0145Parathion
56-38-2
C10H14NO5PS
291.261 g/mol
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  • Aromatic Hydrocarbon
  • Ester
  • Food Toxin
  • Metabolite
  • Organic Compound
  • Organophosphate
  • Pesticide
  • Pollutant
  • Synthetic Compound
Parathion is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholinester...more
Number of Targets: 17
T3D01461,1,2,2-Tetrachloroethane
79-34-5
C2H2Cl4
167.849 g/mol
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  • Food Toxin
  • Industrial Precursor/Intermediate
  • Industrial/Workplace Toxin
  • Organic Compound
  • Organochloride
  • Pesticide
  • Pollutant
  • Refrigerant
  • Solvent
  • Synthetic Compound
The presence of the functional group consisting of a terminal dichloromethyl moiety in a molecule is known to confer toxicity. Moreover, the metabolism of 1,1,2,2-tetr...more
Number of Targets: 39
T3D0147Selenium
7782-49-2
Se
78.960 g/mol
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  • Cosmetic Toxin
  • Food Toxin
  • Household Toxin
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Metabolite
  • Natural Compound
  • Non-Metal
  • Pesticide
  • Pollutant
  • Selenium Compound
Selenium readily substitutes for sulfur in biomolecules and in many biochemical reactions, especially when the concentration of selenium is high and the concentration ...more
Number of Targets: 0
T3D0148Hexachlorocyclohexane, technical Grade
608-73-1
C6H6Cl6
290.830 g/mol
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  • Organic Compound
  • Organochloride
  • Pesticide
  • Pollutant
  • Synthetic Compound
Hexachlorocyclohexane is a neurotoxin that interferes with GABA neurotransmitter function by interacting with the GABA-A receptor-chloride channel complex at the picro...more
Number of Targets: 32
T3D0151O,P'-DDD
53-19-0
C14H10Cl4
320.041 g/mol
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  • Antineoplastic Agent, Hormonal
  • Drug
  • Organic Compound
  • Organochloride
  • Pesticide
  • Synthetic Compound
DDD toxicity occurs via at least four mechanisms, possibly all functioning simultaneously. DDD reduces potassium transport across the membrane. DDD inhibits the inacti...more
Number of Targets: 43
T3D01524,4'-Methylenebis(2-chloroaniline)
101-14-4
C13H12Cl2N2
267.154 g/mol
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  • Amine
  • Organic Compound
  • Organochloride
  • Pesticide
  • Pollutant
  • Synthetic Compound
MBOCA's carcinogenicity is thought to be a result of its ability to bind to DNA, hemoglobin, and serum albumin. One metabolite in particular, N-hydroxy-N,N’-diacetyl M...more
Number of Targets: 49
T3D01561,3-Butadiene
106-99-0
C4H6
54.090 g/mol
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  • Cigarette Toxin
  • Household Toxin
  • Industrial Precursor/Intermediate
  • Industrial/Workplace Toxin
  • Lachrymator
  • Metabolite
  • Organic Compound
  • Pollutant
  • Synthetic Compound
Certain metabolites of 1,3-butadiene have been shown to bind to DNA and nucleoproteins, forming protein-DNA and DNA-DNA crosslinks. Specifically, 1,2-epoxybutene-3 and...more
Number of Targets: 2
T3D0157Ammonia
7664-41-7
H3N
17.031 g/mol
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  • Fertilizer
  • Food Toxin
  • Household Toxin
  • Industrial Precursor/Intermediate
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Lachrymator
  • Metabolite
  • Natural Compound
  • Non-Metal
  • Organic Compound
The topical damage caused by ammonia is probably due mainly to its alkaline properties. Its high water solubility allows it to dissolve in moisture on the mucous membr...more
Number of Targets: 2
T3D01582-Methylnaphthalene
91-57-6
C11H10
142.197 g/mol
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  • Aromatic Hydrocarbon
  • Food Toxin
  • Industrial By-product/Pollutant
  • Industrial/Workplace Toxin
  • Natural Compound
  • Organic Compound
  • Pollutant
  • Polycyclic Aromatic Hydrocarbon
The ability of PAH's to bind to blood proteins such as albumin allows them to be transported throughout the body. Many PAH's induce the expression of cytochrome P450 e...more
Number of Targets: 4
T3D01591,4-Dichlorobenzene
106-46-7
C6H4Cl2
147.002 g/mol
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  • Aromatic Hydrocarbon
  • Food Toxin
  • Household Toxin
  • Industrial Precursor/Intermediate
  • Industrial/Workplace Toxin
  • Lachrymator
  • Metabolite
  • Organic Compound
  • Organochloride
  • Pesticide
  • Pollutant
  • Synthetic Compound
The hepatotoxicity and nephrotoxicity observed in laboratory animals are likely due to the formation of toxic intermediates formed while converting 1,4-DCB to 2,5-dich...more
Number of Targets: 40
T3D01601,1-Dichloroethane
75-34-3
C2H4Cl2
98.959 g/mol
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  • Industrial Precursor/Intermediate
  • Industrial/Workplace Toxin
  • Organic Compound
  • Organochloride
  • Pollutant
  • Solvent
  • Synthetic Compound
The limited information available about 1,1-dichloroethane suggests that it may be nephrotoxic, fetotoxic, and possibly carcinogenic. 1,1-Dichloroethane has been obser...more
Number of Targets: 40
T3D0161Acenaphthene
83-32-9
C12H10
154.208 g/mol
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  • Aromatic Hydrocarbon
  • Food Toxin
  • Industrial By-product/Pollutant
  • Industrial/Workplace Toxin
  • Natural Compound
  • Organic Compound
  • Pollutant
  • Polycyclic Aromatic Hydrocarbon
The ability of PAH's to bind to blood proteins such as albumin allows them to be transported throughout the body. Many PAH's induce the expression of cytochrome P450 e...more
Number of Targets: 3
T3D01621,2,3,4,6,7,8,9-Octachlorodibenzofuran
39001-02-0
C12Cl8O
443.752 g/mol
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  • Aromatic Hydrocarbon
  • Chlorinated Dibenzofuran
  • Dibenzofuran
  • Industrial By-product/Pollutant
  • Industrial/Workplace Toxin
  • Lachrymator
  • Organic Compound
  • Organochloride
  • Pesticide
  • Pollutant
  • Synthetic Compound
Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more
Number of Targets: 2
T3D01631,1,2-Trichloroethane
79-00-5
C2H3Cl3
133.404 g/mol
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  • Industrial/Workplace Toxin
  • Lachrymator
  • Organic Compound
  • Organochloride
  • Pollutant
  • Solvent
  • Synthetic Compound
Acyl chlorides and free radicals formed during the metabolism of 1,1,2-trichloroethane are reactive metabolites that can bind to proteins and nucleic acids (DNA, RNA),...more
Number of Targets: 5
T3D0165Hexachlorocyclopentadiene
77-47-4
C5Cl6
272.772 g/mol
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  • Food Toxin
  • Industrial Precursor/Intermediate
  • Industrial/Workplace Toxin
  • Organic Compound
  • Organochloride
  • Pesticide
  • Pollutant
  • Synthetic Compound
HCCPD may interact with the microsomes that binds to secretory molecules and changes their ability to be transported from the cell. It can be postulated, that some of ...more
Number of Targets: 42
T3D01661,2,3,4,6,7,8-Heptachlorodibenzofuran
38998-75-3
C12HCl7O
409.307 g/mol
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  • Aromatic Hydrocarbon
  • Chlorinated Dibenzofuran
  • Dibenzofuran
  • Industrial By-product/Pollutant
  • Industrial/Workplace Toxin
  • Lachrymator
  • Organic Compound
  • Organochloride
  • Pesticide
  • Pollutant
  • Synthetic Compound
Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more
Number of Targets: 2
T3D01671,2-Diphenylhydrazine
122-66-7
C12H12N2
184.237 g/mol
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  • Amine
  • Aromatic Hydrocarbon
  • Hydrazine
  • Industrial/Workplace Toxin
  • Lachrymator
  • Organic Compound
  • Organochloride
  • Pollutant
  • Synthetic Compound
Two of the known metabolites, aniline and benzidine, may contribute to the toxicity and/or carcinogenicity of 1,2-diphenylhydrazine. Nonneoplastic liver lesions, hepat...more
Number of Targets: 3
T3D01682,3,4,7,8-Pentachlorodibenzofuran
57117-31-4
C12H3Cl5O
340.417 g/mol
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  • Aromatic Hydrocarbon
  • Chlorinated Dibenzofuran
  • Dibenzofuran
  • Industrial By-product/Pollutant
  • Industrial/Workplace Toxin
  • Lachrymator
  • Organic Compound
  • Organochloride
  • Pesticide
  • Pollutant
  • Synthetic Compound
Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more
Number of Targets: 2
T3D0170p-Cresol
106-44-5
C7H8O
108.138 g/mol
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  • Aromatic Hydrocarbon
  • Disinfectant
  • Food Toxin
  • Household Toxin
  • Industrial/Workplace Toxin
  • Metabolite
  • Natural Compound
  • Organic Compound
  • Pollutant
  • Solvent
  • Uremic Toxin
p-Cresol is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholinestera...more
Number of Targets: 5
T3D01721,2-Dichlorobenzene
95-50-1
C6H4Cl2
147.002 g/mol
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  • Aromatic Hydrocarbon
  • Food Toxin
  • Household Toxin
  • Industrial Precursor/Intermediate
  • Industrial/Workplace Toxin
  • Organic Compound
  • Organochloride
  • Pollutant
  • Solvent
  • Synthetic Compound
1,2-DCB was found to covalently bind to DNA, RNA, and proteins of liver, kidney, lung, and stomach. (L395)
Number of Targets: 42
T3D0173trans-1,2-Dichloroethene
156-60-5
C2H2Cl2
96.943 g/mol
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  • Industrial/Workplace Toxin
  • Lachrymator
  • Organic Compound
  • Organochloride
  • Pollutant
  • Solvent
  • Synthetic Compound
Trans-1,2-dichloroethene is a volatile, lipophilic molecule that easily moves through the respiratory and gastrointestinal systems. It has a high affinity for lipids a...more
Number of Targets: 4
T3D0174Indeno(1,2,3-cd)pyrene
193-39-5
C22H12
276.331 g/mol
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  • Aromatic Hydrocarbon
  • Cigarette Toxin
  • Food Toxin
  • Industrial By-product/Pollutant
  • Industrial/Workplace Toxin
  • Natural Compound
  • Organic Compound
  • Pollutant
  • Polycyclic Aromatic Hydrocarbon
The ability of PAH's to bind to blood proteins such as albumin allows them to be transported throughout the body. Many PAH's induce the expression of cytochrome P450 e...more
Number of Targets: 3
Displaying toxins 126 - 150 of 3678 in total