Tmic
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Displaying toxins 151 - 175 of 3678 in total
T3DB ID Name
CAS Number
Formula
Weight
StructureTypeMechanism of Toxicity
T3D0176Carbon disulfide
75-15-0
CS2
76.141 g/mol
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  • Food Toxin
  • Industrial/Workplace Toxin
  • Metabolite
  • Natural Compound
  • Organic Compound
  • Pollutant
  • Solvent
Carbon disulfide is a potent nerve toxin and also affect liver enzymes, particularly those related to lipid metabolism. The increases in serum cholesterol that are som...more
Number of Targets: 3
T3D01772,3,4,5-Tetrachlorophenol
25167-83-3
C6H2Cl4O
231.891 g/mol
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  • Aromatic Hydrocarbon
  • Food Toxin
  • Industrial/Workplace Toxin
  • Lachrymator
  • Organic Compound
  • Organochloride
  • Synthetic Compound
Tetrachlorophenols decrease or block ATP production without blocking the electron transport chain. Thus the poisons uncouple phosphorylation from oxidation. Free energ...more
Number of Targets: 2
T3D0178Americium
7440-35-9
Am
243.000 g/mol
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  • Americium Compound
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Metal
  • Pollutant
  • Radioactive
  • Synthetic Compound
Americium toxicity results primarily from the damage done by the alpha particle emitted during radioactive decay. This alpha particle has very limited penetration in t...more
Number of Targets: 1
T3D0179Uranium-233
13968-55-3
U
233.040 g/mol
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  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Metal
  • Natural Compound
  • Pollutant
  • Radioactive
  • Radioactive Isotope
  • Uranium Compound
Uranium is combined with either bicarbonate or a plasma protein in the blood but once in the kidney, it is released and forms complexes with phosphate ligands and prot...more
Number of Targets: 1
T3D0180Palladium
7440-05-03
Pd
106.420 g/mol
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  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Metabolite
  • Metal
  • Natural Compound
  • Nickel Compound
  • Palladium Compound
Palladium ions are able to inhibit most major cellular fuctions. They form strong complexes with both inorganic and organic ligands, substitute essential ions, bind to...more
Number of Targets: 5
T3D0182Phenol
108-95-2
C6H6O
94.111 g/mol
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  • Anti-Infective Agent, Local
  • Antipsoriatic Agent
  • Antiseptic Agent
  • Aromatic Hydrocarbon
  • Disinfectant
  • Drug
  • Food Toxin
  • Household Toxin
  • Industrial/Workplace Toxin
  • Metabolite
  • Natural Compound
  • Organic Compound
  • Pollutant
  • Sclerosing Solution
Phenol is irritating and corrosive at high concentrations. Phenol impairs the stratum corneum and produces coagulation necrosis by denaturing and precipitating protein...more
Number of Targets: 13
T3D0183Chloroethane
75-00-3
C2H5Cl
64.514 g/mol
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  • Household Toxin
  • Industrial Precursor/Intermediate
  • Industrial/Workplace Toxin
  • Organic Compound
  • Organochloride
  • Pollutant
  • Synthetic Compound
Chloroethane targets the central nervous system and the heart. The lipophilicity of chloroethane suggests it acts upon the lipid layer of cellular membrane or the hydr...more
Number of Targets: 2
T3D0184Acetone
67-64-1
C3H6O
58.079 g/mol
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  • Food Toxin
  • Household Toxin
  • Industrial Precursor/Intermediate
  • Industrial/Workplace Toxin
  • Ketone
  • Lachrymator
  • Metabolite
  • Natural Compound
  • Organic Compound
  • Solvent
Since acetone is highly water soluble, it is readily taken up by the blood and widely distributed to body tissues. Acetone may interfere with the composition of the me...more
Number of Targets: 1
T3D0185p-Xylene
106-42-3
C8H10
106.165 g/mol
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  • Aromatic Hydrocarbon
  • Food Toxin
  • Household Toxin
  • Industrial/Workplace Toxin
  • Lachrymator
  • Metabolite
  • Natural Compound
  • Organic Compound
  • Pollutant
  • Solvent
p-Xylene is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholinestera...more
Number of Targets: 4
T3D0187Aluminum
7429-90-5
Al
26.982 g/mol
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  • Aluminum Compound
  • Cosmetic Toxin
  • Drug
  • Food Toxin
  • Household Toxin
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Metabolite
  • Metal
  • Natural Compound
The main targets of aluminum are the central nervous system and bones. Aluminum binds to dietary phosphorus and impairs gastrointestinal absorption of phosphorus. The ...more
Number of Targets: 6
T3D0189Carbon monoxide
630-08-0
CO
28.010 g/mol
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  • Food Toxin
  • Industrial By-product/Pollutant
  • Industrial/Workplace Toxin
  • Metabolite
  • Natural Compound
  • Organic Compound
  • Pollutant
Carbon monoxide possesses a higher affinity than oxygen for hemoglobin, leading to the formation of carboxyhemoglobin, this provoking anoxemia. Carbon monoxide also bi...more
Number of Targets: 30
T3D0191Hydrogen sulfide
7783-06-04
H2S
34.081 g/mol
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  • Bacterial Toxin
  • Household Toxin
  • Industrial Precursor/Intermediate
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Lachrymator
  • Metabolite
  • Natural Compound
  • Non-Metal
Although very pungent at first, hydrogen sulfide quickly deadens the sense of smell, so potential victims may be unaware of its presence until it is too late. Hydrogen...more
Number of Targets: 1
T3D0194Bis(2-methoxyethyl) phthalate
34006-76-3
C13H16O4
236.264 g/mol
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  • Aromatic Hydrocarbon
  • Cosmetic Toxin
  • Ester
  • Ether
  • Household Toxin
  • Industrial/Workplace Toxin
  • Organic Compound
  • Phthalate
  • Plasticizer
  • Synthetic Compound
Phthalate esters are endocrine disruptors. They decrease foetal testis testosterone production and reduce the expression of steroidogenic genes by decreasing mRNA expr...more
Number of Targets: 0
T3D0195Benzyl butyl phthalate
85-68-7
C19H20O4
312.360 g/mol
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  • Aromatic Hydrocarbon
  • Cosmetic Toxin
  • Ester
  • Ether
  • Household Toxin
  • Industrial/Workplace Toxin
  • Organic Compound
  • Phthalate
  • Plasticizer
  • Pollutant
  • Synthetic Compound
Phthalate esters are endocrine disruptors. They decrease foetal testis testosterone production and reduce the expression of steroidogenic genes by decreasing mRNA expr...more
Number of Targets: 11
T3D0196o-Cresol
95-48-7
C7H8O
108.138 g/mol
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  • Aromatic Hydrocarbon
  • Disinfectant
  • Food Toxin
  • Household Toxin
  • Industrial/Workplace Toxin
  • Metabolite
  • Natural Compound
  • Organic Compound
  • Pollutant
  • Solvent
Target organs of ingested cresols in humans are the blood, kidneys, lungs, liver, heart, and central nervous system. Cresols impair the stratum corneum and produce coa...more
Number of Targets: 3
T3D0198Vanadium
7440-62-2
V
50.940 g/mol
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  • Food Toxin
  • Inorganic Compound
  • Metabolite
  • Metal
  • Natural Compound
  • Vanadium Compound
Vanadium damages alveolar macrophages by decreasing the macrophage membrane integrity, thus impairing the cell's phagocytotic ability and viability. The pentavalent fo...more
Number of Targets: 47
T3D0199N-Nitrosodimethylamine
62-75-9
C2H6N2O
74.082 g/mol
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  • Amine
  • Cigarette Toxin
  • Food Toxin
  • Household Toxin
  • Industrial By-product/Pollutant
  • Industrial/Workplace Toxin
  • Metabolite
  • Nitrite
  • Organic Compound
  • Pesticide
  • Pollutant
  • Synthetic Compound
The mechanism of NDMAinduced liver toxicity is not clearly understood but may be related to alkylation of cellular protein. (L1207)
Number of Targets: 0
T3D02001,2,4-Trichlorobenzene
120-82-1
C6H3Cl3
181.447 g/mol
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  • Aromatic Hydrocarbon
  • Industrial/Workplace Toxin
  • Lachrymator
  • Organic Compound
  • Organochloride
  • Pesticide
  • Pollutant
  • Solvent
  • Synthetic Compound
Trichlorobenzene may uncouple mitochondrial oxidative phosphorylation, inducing potassium ion release and inhibiting respiratory control. It's metabolites may covalent...more
Number of Targets: 39
T3D02072,3,7,8-Tetrachlorodibenzofuran
51207-31-9
C12H4Cl4O
305.972 g/mol
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  • Aromatic Hydrocarbon
  • Chlorinated Dibenzofuran
  • Dibenzofuran
  • Industrial By-product/Pollutant
  • Industrial/Workplace Toxin
  • Lachrymator
  • Organic Compound
  • Organochloride
  • Pesticide
  • Pollutant
  • Synthetic Compound
Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more
Number of Targets: 2
T3D02092,4-Dichlorophenol
120-83-2
C6H4Cl2O
163.001 g/mol
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  • Aromatic Hydrocarbon
  • Food Toxin
  • Industrial Precursor/Intermediate
  • Industrial/Workplace Toxin
  • Metabolite
  • Organic Compound
  • Organochloride
  • Pesticide
  • Pollutant
  • Synthetic Compound
Chlorophenols have moderately high lipophilicity. Absorption through the gastrointestinal tract is by simple diffusion and is expected to be both rapid and virtually c...more
Number of Targets: 3
T3D02101,4-Dioxane
123-91-1
C4H8O2
88.105 g/mol
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  • Cosmetic Toxin
  • Ether
  • Household Toxin
  • Industrial/Workplace Toxin
  • Lachrymator
  • Organic Compound
  • Pollutant
  • Solvent
  • Synthetic Compound
Though the mechanism of toxicity of 1,4-dioxane has not yet been elucidated, it is known that its carcinogenic effects are caused by a non-genotoxic mechanism that is ...more
Number of Targets: 4
T3D0211Fluorine
7782-41-4
F
18.999 g/mol
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  • Food Toxin
  • Halogen
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Metabolite
  • Natural Compound
  • Non-Metal
Fluoride ions are incorporated into bone by substituting for hydroxyl groups in the carbonate-apatite structure to produce hydroxyfluorapatite, thus altering the miner...more
Number of Targets: 7
T3D0212Nitrite
14797-65-0
NO2
46.006 g/mol
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  • Food Toxin
  • Inorganic Compound
  • Metabolite
  • Natural Compound
  • Nitrite
  • Non-Metal
  • Pesticide
Nitrite causes the autocatalytic oxidation of oxyhemoglobin to hydrogen peroxide and methemoglobin. This elevation of methemoglobin levels is a condition known as meth...more
Number of Targets: 9
T3D0213Cesium-137
10045-97-3
Cs
136.907 g/mol
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  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Metal
  • Natural Compound
  • Pollutant
  • Radioactive
  • Radioactive Isotope
Highly penetrating gamma rays are the major cause of damage to tissues and internal organs following external overexposure to radioactive cesium. Once radioactive cesi...more
Number of Targets: 1
T3D0214Silver
7440-22-4
Ag
107.868 g/mol
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  • Food Toxin
  • Household Toxin
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Metabolite
  • Metal
  • Natural Compound
  • Pollutant
  • Silver Compound
Metallic silver is oxidized and may deposit in the tissues, causing arygria. The silver ion is known to inhibit glutathione peroxidase and NA+,K+-ATPase activity, resp...more
Number of Targets: 18
Displaying toxins 151 - 175 of 3678 in total