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Displaying types 1 - 10 of 483 in total

14-alpha Demethylase Inhibitor (5)

T3DB IDCommon nameCAS NumberMechanism of Toxicity
T3D2729Clotrimazole23593-75-1Clotrimazole interacts with yeast 14-α demethylase, a cytochrome P-450 enzyme that converts lanos...more
T3D2956Tioconazole65899-73-2Tioconazole interacts with 14-α demethylase, a cytochrome P-450 enzyme that converts lanosterol t...more
T3D2961Ketoconazole65277-42-1Ketoconazole interacts with 14-α demethylase, a cytochrome P-450 enzyme necessary for the convers...more
T3D2988Miconazole22916-47-8Miconazole interacts with 14-α demethylase, a cytochrome P-450 enzyme necessary to convert lanost...more
T3D3516Itraconazole84625-61-6Itraconazole interacts with 14-α demethylase, a cytochrome P-450 enzyme necessary to convert lano...more

5-alpha Reductase Inhibitor (1)

T3DB IDCommon nameCAS NumberMechanism of Toxicity
T3D4820Finasteride98319-26-7The mechanism of action of Finasteride is based on its preferential inhibition of Type II 5a-redu...more

Abortifacient Agent (1)

T3DB IDCommon nameCAS NumberMechanism of Toxicity
T3D2486Methotrexate59-05-2Methotrexate anti-tumor activity is a result of the inhibition of folic acid reductase, leading t...more

Abortifacient Agent, Nonsteroidal (1)

T3DB IDCommon nameCAS NumberMechanism of Toxicity
T3D2486Methotrexate59-05-2Methotrexate anti-tumor activity is a result of the inhibition of folic acid reductase, leading t...more

Abortifacient Agent, Steroidal (1)

T3DB IDCommon nameCAS NumberMechanism of Toxicity
T3D2907Mifepristone84371-65-3Mifepristone is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhib...more

Acaricide (7)

T3DB IDCommon nameCAS NumberMechanism of Toxicity
T3D3798Bifenazate149877-41-8Not Available
T3D3811Clofentezine74115-24-5Not Available
T3D3907Propargite2312-35-8Not Available
T3D4489Coumaphos56-72-4Coumaphos is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibito...more
T3D4515Hexythiazox78587-05-0Not Available
T3D4536Spirodiclofen148477-71-8Not Available
T3D4873(±)-2-(1-Methylpropyl)-4,6-dinitrophenol88-85-7Not Available

Adenosine Deaminase Inhibitor (1)

T3DB IDCommon nameCAS NumberMechanism of Toxicity
T3D2822Pentostatin53910-25-1Pentostatin is a potent transition state inhibitor of adenosine deaminase (ADA), the greatest act...more

Adhesive (1)

T3DB IDCommon nameCAS NumberMechanism of Toxicity
T3D2403Hexane110-54-3Hexane's toxicity is caused by it neurotoxic metabolite, 2,5-hexanedione. It damages the central ...more

Adjuvant (7)

T3DB IDCommon nameCAS NumberMechanism of Toxicity
T3D2784Secobarbital76-73-3Secobarbital binds at a distinct binding site associated with a Cl- ionopore at the GABAA recepto...more
T3D2795Meperidine57-42-1Meperidine is primarily a kappa-opiate receptor agonist and also has local anesthetic effects. Me...more
T3D2810Cimetidine51481-61-9Cimetidine binds to an H2-receptor located on the basolateral membrane of the gastric parietal ce...more
T3D2877Scopolamine51-34-3Scopolamine acts by interfering with the transmission of nerve impulses by acetylcholine in the p...more
T3D2898Fentanyl437-38-7Opiate receptors are coupled with G-protein receptors and function as both positive and negative ...more
T3D3015Oxymorphone76-41-5Oxymorphone interacts predominantly with the opioid mu-receptor. These mu-binding sites are discr...more
T3D3039Hexobarbital56-29-1Hexobarbital binds at a distinct binding site associated with a Cl- ionopore at the GABA-A recept...more

Adjuvant, Anesthesia (13)

T3DB IDCommon nameCAS NumberMechanism of Toxicity
T3D2564Triazolam28911-01-5Benzodiazepines bind nonspecifically to bezodiazepine receptors BNZ1, which mediates sleep, and B...more
T3D2719Temazepam846-50-4Benzodiazepines bind nonspecifically to benzodiazepine receptors, which affects muscle relaxation...more
T3D2745Pentobarbital76-74-4Pentobarbital binds at a distinct binding site associated with a Cl- ionopore at the GABAA recept...more
T3D2784Secobarbital76-73-3Secobarbital binds at a distinct binding site associated with a Cl- ionopore at the GABAA recepto...more
T3D2795Meperidine57-42-1Meperidine is primarily a kappa-opiate receptor agonist and also has local anesthetic effects. Me...more
T3D2804Chlordiazepoxide58-25-3Chlordiazepoxide binds to stereospecific benzodiazepine (BZD) binding sites on GABA (A) receptor ...more
T3D2850Pentazocine359-83-1The preponderance of evidence suggests that pentazocine antagonizes the opioid effects by competi...more
T3D2859Midazolam59467-70-8It is thought that the actions of benzodiazepines such as midazolam are mediated through the inhi...more
T3D2865Sufentanil56030-54-7Opiate receptors are coupled with G-protein receptors and function as both positive and negative ...more
T3D2877Scopolamine51-34-3Scopolamine acts by interfering with the transmission of nerve impulses by acetylcholine in the p...more
T3D2898Fentanyl437-38-7Opiate receptors are coupled with G-protein receptors and function as both positive and negative ...more
T3D2903Diazepam439-14-5Benzodiazepines bind nonspecifically to benzodiazepine receptors which mediate sleep, affects mus...more
T3D3015Oxymorphone76-41-5Oxymorphone interacts predominantly with the opioid mu-receptor. These mu-binding sites are discr...more
Displaying types 1 - 10 of 483 in total