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Browsing Toxin Types
14-alpha Demethylase Inhibitor (5)
T3DB ID | Common name | CAS Number | Mechanism of Toxicity |
---|---|---|---|
T3D2729 | Clotrimazole | 23593-75-1 | Clotrimazole interacts with yeast 14-α demethylase, a cytochrome P-450 enzyme that converts lanos...more |
T3D2956 | Tioconazole | 65899-73-2 | Tioconazole interacts with 14-α demethylase, a cytochrome P-450 enzyme that converts lanosterol t...more |
T3D2961 | Ketoconazole | 65277-42-1 | Ketoconazole interacts with 14-α demethylase, a cytochrome P-450 enzyme necessary for the convers...more |
T3D2988 | Miconazole | 22916-47-8 | Miconazole interacts with 14-α demethylase, a cytochrome P-450 enzyme necessary to convert lanost...more |
T3D3516 | Itraconazole | 84625-61-6 | Itraconazole interacts with 14-α demethylase, a cytochrome P-450 enzyme necessary to convert lano...more |
5-alpha Reductase Inhibitor (1)
T3DB ID | Common name | CAS Number | Mechanism of Toxicity |
---|---|---|---|
T3D4820 | Finasteride | 98319-26-7 | The mechanism of action of Finasteride is based on its preferential inhibition of Type II 5a-redu...more |
Abortifacient Agent (1)
T3DB ID | Common name | CAS Number | Mechanism of Toxicity |
---|---|---|---|
T3D2486 | Methotrexate | 59-05-2 | Methotrexate anti-tumor activity is a result of the inhibition of folic acid reductase, leading t...more |
Abortifacient Agent, Nonsteroidal (1)
T3DB ID | Common name | CAS Number | Mechanism of Toxicity |
---|---|---|---|
T3D2486 | Methotrexate | 59-05-2 | Methotrexate anti-tumor activity is a result of the inhibition of folic acid reductase, leading t...more |
Abortifacient Agent, Steroidal (1)
T3DB ID | Common name | CAS Number | Mechanism of Toxicity |
---|---|---|---|
T3D2907 | Mifepristone | 84371-65-3 | Mifepristone is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhib...more |
Acaricide (7)
T3DB ID | Common name | CAS Number | Mechanism of Toxicity |
---|---|---|---|
T3D3798 | Bifenazate | 149877-41-8 | Not Available |
T3D3811 | Clofentezine | 74115-24-5 | Not Available |
T3D3907 | Propargite | 2312-35-8 | Not Available |
T3D4489 | Coumaphos | 56-72-4 | Coumaphos is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibito...more |
T3D4515 | Hexythiazox | 78587-05-0 | Not Available |
T3D4536 | Spirodiclofen | 148477-71-8 | Not Available |
T3D4873 | (±)-2-(1-Methylpropyl)-4,6-dinitrophenol | 88-85-7 | Not Available |
Adenosine Deaminase Inhibitor (1)
T3DB ID | Common name | CAS Number | Mechanism of Toxicity |
---|---|---|---|
T3D2822 | Pentostatin | 53910-25-1 | Pentostatin is a potent transition state inhibitor of adenosine deaminase (ADA), the greatest act...more |
Adhesive (1)
T3DB ID | Common name | CAS Number | Mechanism of Toxicity |
---|---|---|---|
T3D2403 | Hexane | 110-54-3 | Hexane's toxicity is caused by it neurotoxic metabolite, 2,5-hexanedione. It damages the central ...more |
Adjuvant (7)
T3DB ID | Common name | CAS Number | Mechanism of Toxicity |
---|---|---|---|
T3D2784 | Secobarbital | 76-73-3 | Secobarbital binds at a distinct binding site associated with a Cl- ionopore at the GABAA recepto...more |
T3D2795 | Meperidine | 57-42-1 | Meperidine is primarily a kappa-opiate receptor agonist and also has local anesthetic effects. Me...more |
T3D2810 | Cimetidine | 51481-61-9 | Cimetidine binds to an H2-receptor located on the basolateral membrane of the gastric parietal ce...more |
T3D2877 | Scopolamine | 51-34-3 | Scopolamine acts by interfering with the transmission of nerve impulses by acetylcholine in the p...more |
T3D2898 | Fentanyl | 437-38-7 | Opiate receptors are coupled with G-protein receptors and function as both positive and negative ...more |
T3D3015 | Oxymorphone | 76-41-5 | Oxymorphone interacts predominantly with the opioid mu-receptor. These mu-binding sites are discr...more |
T3D3039 | Hexobarbital | 56-29-1 | Hexobarbital binds at a distinct binding site associated with a Cl- ionopore at the GABA-A recept...more |
Adjuvant, Anesthesia (13)
T3DB ID | Common name | CAS Number | Mechanism of Toxicity |
---|---|---|---|
T3D2564 | Triazolam | 28911-01-5 | Benzodiazepines bind nonspecifically to bezodiazepine receptors BNZ1, which mediates sleep, and B...more |
T3D2719 | Temazepam | 846-50-4 | Benzodiazepines bind nonspecifically to benzodiazepine receptors, which affects muscle relaxation...more |
T3D2745 | Pentobarbital | 76-74-4 | Pentobarbital binds at a distinct binding site associated with a Cl- ionopore at the GABAA recept...more |
T3D2784 | Secobarbital | 76-73-3 | Secobarbital binds at a distinct binding site associated with a Cl- ionopore at the GABAA recepto...more |
T3D2795 | Meperidine | 57-42-1 | Meperidine is primarily a kappa-opiate receptor agonist and also has local anesthetic effects. Me...more |
T3D2804 | Chlordiazepoxide | 58-25-3 | Chlordiazepoxide binds to stereospecific benzodiazepine (BZD) binding sites on GABA (A) receptor ...more |
T3D2850 | Pentazocine | 359-83-1 | The preponderance of evidence suggests that pentazocine antagonizes the opioid effects by competi...more |
T3D2859 | Midazolam | 59467-70-8 | It is thought that the actions of benzodiazepines such as midazolam are mediated through the inhi...more |
T3D2865 | Sufentanil | 56030-54-7 | Opiate receptors are coupled with G-protein receptors and function as both positive and negative ...more |
T3D2877 | Scopolamine | 51-34-3 | Scopolamine acts by interfering with the transmission of nerve impulses by acetylcholine in the p...more |
T3D2898 | Fentanyl | 437-38-7 | Opiate receptors are coupled with G-protein receptors and function as both positive and negative ...more |
T3D2903 | Diazepam | 439-14-5 | Benzodiazepines bind nonspecifically to benzodiazepine receptors which mediate sleep, affects mus...more |
T3D3015 | Oxymorphone | 76-41-5 | Oxymorphone interacts predominantly with the opioid mu-receptor. These mu-binding sites are discr...more |