2551 alpha-Cobratoxin alpha-Cobratoxin is a peptide toxin produced by certain cobras of the Naja genus, such as the Monocled cobra (Naja kaouthia). It is a muscle-type nicotinic acetylcholine receptor (nAChR) antagonist, which causes paralysis by preventing the binding of acetylcholine to the nAChR. (L1046) 769933-79-1 16132280 7830.959999999996 Clear solution. >10 mg/mL Injection (sting/bite) (L1814) alpha-Cobratoxin is a muscle-type nicotinic acetylcholine receptor (nAChR) antagonist. It causes paralysis by preventing the binding of acetylcholine to the nAChR, as the nAChR is needed for synaptic transmission both in the central nervous system and at the neuromuscular junction. (L1046) Free toxin may be removed by opsonization via the reticuloendothelial system (primarily the liver and kidneys) or it may be degraded through cellular internalization via the lysosomes. Lysosomes are membrane-enclosed organelles that contain an array of digestive enzymes, including several proteases. LD50: 4 ug/kg (Mouse) (L1046) No indication of carcinogenicity to humans (not listed by IARC). alpha-Cobratoxin is a peptide toxin produced by certain cobras of the Naja genus, such as the Monocled cobra (Naja kaouthia). (L1046) Naja cobras have a strongly neurotoxic venom, which attacks the nervous system, causing paralysis, and many also have hemotoxic features which causes swelling, necrosis and has a significant anticoagulant effect. Naja bites can be fatal to humans. (L1047) Naja bites cause pain and swelling at the site of the bite. The venom is alsoa severe irritant to the skin and eyes. (L1047) 2009-07-03T22:19:05Z 2014-12-24T20:25:38Z P01391 alpha-Cobratoxin 1CTX true Exogenous Liquid 17288939 1ctx_bio_r_500.jpg image/jpeg 36006 2014-10-14T18:12:55Z BSEQ0008439