2670 Hanatoxin Hanatoxin is a peptide toxin produced by the Chilean rose tarantula (Grammostola rosea). It inhibits voltage-gated potassium channels by altering the gating energetics, and can also inhibit calcium channels. (T170, L1812) 170780-01-5 4120.69 Clear solution. >10 mg/mL Injection (sting/bite) (L1812) Hanatoxin inhibits voltage-gated potassium channels by altering the gating energetics, which it does by occupying multiple binding sites on the channel. It can also inhibit calcium channels. (T170, L1812) Free toxin may be removed by opsonization via the reticuloendothelial system (primarily the liver and kidneys) or it may be degraded through cellular internalization via the lysosomes. Lysosomes are membrane-enclosed organelles that contain an array of digestive enzymes, including several proteases. No indication of carcinogenicity to humans (not listed by IARC). Hanatoxin is a peptide toxin produced by the Chilean rose tarantula (Grammostola rosea). (L1812) Hanatoxin is neurotoxic. (T170, L1812) Tarantula bites can be very painful. In some individuals they may cause an allergic reaction, which is usually anaphylactic and will have symptoms such as breathing difficulties or chest pain. (L1823) 2009-07-06T21:35:30Z 2014-12-24T20:25:47Z P56852 Hanatoxin 1D1H true Exogenous Liquid 1d1h_asym_r_500.jpg image/jpeg 21157 2014-10-14T18:13:49Z BSEQ0008499