<?xml version="1.0" encoding="UTF-8"?>
<compound>
  <id type="integer">3106</id>
  <title>T3D3064</title>
  <common-name>Chlophedianol</common-name>
  <description>Chlophedianol is only found in individuals that have used or taken this drug. It is a centrally-acting cough suppressant available in Canada under the trade name Ulone. It is not available in the United States. Chlophedianol suppresses the cough reflex by a direct effect on the cough center in the medulla of the brain.</description>
  <cas>791-35-5</cas>
  <pubchem-id>2795</pubchem-id>
  <chemical-formula>C17H20ClNO</chemical-formula>
  <weight>289.123340</weight>
  <appearance>White powder.</appearance>
  <melting-point>120°C</melting-point>
  <boiling-point nil="true"/>
  <density nil="true"/>
  <solubility>6.21e-02 g/L</solubility>
  <specific-gravity nil="true"/>
  <flash-point nil="true"/>
  <vapour-pressure nil="true"/>
  <route-of-exposure>Oral</route-of-exposure>
  <target nil="true"/>
  <mechanism-of-toxicity>Suppresses the cough reflex by a direct effect on the cough center in the medulla of the brain.</mechanism-of-toxicity>
  <metabolism>Hepatic.</metabolism>
  <toxicity></toxicity>
  <lethaldose nil="true"/>
  <carcinogenicity>No indication of carcinogenicity to humans (not listed by IARC).</carcinogenicity>
  <use-source>Used in the treatment of dry cough.</use-source>
  <min-risk-level nil="true"/>
  <health-effects>May have anticholinergic effects at high doses.</health-effects>
  <symptoms></symptoms>
  <treatment nil="true"/>
  <created-at type="dateTime">2009-07-21T20:28:58Z</created-at>
  <updated-at type="dateTime">2014-12-24T20:25:56Z</updated-at>
  <interacting-proteins nil="true"/>
  <wikipedia>Clofedanol</wikipedia>
  <uniprot-id></uniprot-id>
  <kegg-compound-id></kegg-compound-id>
  <omim-id></omim-id>
  <chebi-id>775264</chebi-id>
  <biocyc-id></biocyc-id>
  <ctd-id nil="true"/>
  <stitch-id>Chlophedianol</stitch-id>
  <drugbank-id>DB04837</drugbank-id>
  <pdb-id></pdb-id>
  <actor-id nil="true"/>
  <organism nil="true"/>
  <export type="boolean">true</export>
  <metabolizing-proteins nil="true"/>
  <transporting-proteins nil="true"/>
  <moldb-smiles>CN(C)CCC(O)(C1=CC=CC=C1)C1=CC=CC=C1Cl</moldb-smiles>
  <moldb-formula>C17H20ClNO</moldb-formula>
  <moldb-inchi>InChI=1/C17H20ClNO/c1-19(2)13-12-17(20,14-8-4-3-5-9-14)15-10-6-7-11-16(15)18/h3-11,20H,12-13H2,1-2H3</moldb-inchi>
  <moldb-inchikey>InChIKey=WRCHFMBCVFFYEQ-UHFFFAOYNA-N</moldb-inchikey>
  <moldb-average-mass type="decimal">289.8</moldb-average-mass>
  <moldb-mono-mass type="decimal">289.123341974</moldb-mono-mass>
  <origin>Exogenous</origin>
  <state>Solid</state>
  <logp nil="true"/>
  <hmdb-id>HMDB15585</hmdb-id>
  <chembl-id nil="true"/>
  <chemspider-id>2693</chemspider-id>
  <structure-image-file-name nil="true"/>
  <structure-image-content-type nil="true"/>
  <structure-image-file-size type="integer" nil="true"/>
  <structure-image-updated-at type="dateTime" nil="true"/>
  <biodb-id nil="true"/>
  <synthesis-reference>&lt;p&gt;Lorenz, R., Gosswald, R. and Henecka, H.; US. Patent 3,031,377; April 24, 1962; assigned&lt;br /&gt;
to Farbenfabriken Bayer AG, Germany.&lt;/p&gt;</synthesis-reference>
  <structure-image-caption nil="true"/>
</compound>
