4752 T3D4697 Iron A metallic element found in certain minerals, in nearly all soils, and in mineral waters. It is an essential constituent of hemoglobin, cytochrome, and other components of respiratory enzyme systems. Its chief functions are in the transport of oxygen to tissue (hemoglobin) and in cellular oxidation mechanisms. Depletion of iron stores may result in iron-deficiency anemia. Iron is used to build up the blood in anemia. 7439-89-6 23925 Fe White powder. 1538°C The efficiency of absorption depends on the salt form, the amount administered, the dosing regimen and the size of iron stores. Subjects with normal iron stores absorb 10% to 35% of an iron dose. Those who are iron deficient may absorb up to 95% of an iron dose. Iron is necessary for the production of hemoglobin. Iron-deficiency can lead to decreased production of hemoglobin and a microcytic, hypochromic anemia. In a young child, 75 milligrams per kilogram is considered extremely dangerous. A dose of 30 milligrams per kilogram can lead to symptoms of toxicity. A peak serum iron concentration of five micrograms or more per ml is associated with moderate to severe poisoning in many. Estimates of a lethal dosage range from 180 milligrams per kilogram and upwards. No indication of carcinogenicity to humans (not listed by IARC). Used in preventing and treating iron-deficiency anemia. 2014-09-11T02:05:26Z 2014-12-24T20:26:55Z http://en.wikipedia.org/wiki/Iron C00023 18248 DB01592 true [Fe] Fe InChI=1S/Fe InChIKey=XEEYBQQBJWHFJM-UHFFFAOYSA-N 55.845 55.934942133 Endogenous Solid HMDB15531 22368 <p>Walter Lugscheider, Paul Mullner, Wilhelm Schiffer, Alois Leutgob, &#8220;Arrangement for producing metals, such as molten pig iron, steel pre-material and ferroalloys.&#8221; U.S. Patent US4617671, issued 0000.</p>