4797 Sodium Tetradecyl Sulfate An anionic surface-active agent used for its wetting properties in industry and used in medicine as an irritant and sclerosing agent for hemorrhoids and varicose veins. 1191-50-0 5248 C14H30O4S White powder. 2.62e-03 g/L Sodium tetradecyl sulfate is a potent toxin for endothelial cells in that brief exposure to even low concentrations are effective in stripping endothelium over a considerable distance and exposing highly thrombogenic endothelium in the process. Diluted sodium tetradecyl sulfate is also able to induce a hypercoagulable state, possibly by selective inhibition of protein C, and can also promote platelet aggregation. LD₅₀=1250 mg/kg (Orally in rat); LD₅₀=3 ml/kg (Skin in rat) No indication of carcinogenicity to humans (not listed by IARC). For the treatment of small uncomplicated varicose veins of the lower extremities that show simple dilation with competent valves. 2014-09-11T05:14:20Z 2014-12-24T20:26:56Z 782257 DB00464 true CCCCCCCCCCCCCCOS(O)(=O)=O C14H30O4S InChI=1S/C14H30O4S/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-18-19(15,16)17/h2-14H2,1H3,(H,15,16,17) InChIKey=URLJMZWTXZTZRR-UHFFFAOYSA-N 294.451 294.186480138 Exogenous Solid HMDB14607 CHEMBL1200354 5058