Kinesin-like protein KIF3C

NameKinesin-like protein KIF3C
SynonymsNot Available
Gene NameKIF3C
OrganismHuman
Amino acid sequence
>lcl|BSEQ0019734|Kinesin-like protein KIF3C
MASKTKASEALKVVARCRPLSRKEEAAGHEQILTMDVKLGQVTLRNPRAAPGELPKTFTF
DAVYDASSKQADLYDETVRPLIDSVLQGFNGTVFAYGQTGTGKTYTMQGTWVEPELRGVI
PNAFEHIFTHISRSQNQQYLVRASYLEIYQEEIRDLLSKEPGKRLELKENPETGVYIKDL
SSFVTKNVKEIEHVMNLGNQTRAVGSTHMNEVSSRSHAIFIITVECSERGSDGQDHIRVG
KLNLVDLAGSERQNKAGPNTAGGAATPSSGGGGGGGGSGGGAGGERPKEASKINLSLSAL
GNVIAALAGNRSTHIPYRDSKLTRLLQDSLGGNAKTIMVATLGPASHSYDESLSTLRFAN
RAKNIKNKPQVNEDPKDTLLREFQEEIARLKAQLEKRGMLGKRPRRKSSRRKKAVSAPPG
YPEGPVIEAWVAEEEDDNNNNHRPPQPILESALEKNMENYLQEQKERLEEEKAAIQDDRS
LVSEEKQKLLEEKEKMLEDLRREQQATELLAAKYKAMESKLLIGGRNIMDHTNEQQKMLE
LKRQEIAEQKRREREMQQEMMLRDEETMELRGTYTSLQQEVEVKTKKLKKLYAKLQAVKA
EIQDQHDEYIRVRQDLEEAQNEQTRELKLKYLIIENFIPPEEKNKIMNRLFLDCEEEQWK
FQPLVPAGVSSSQMKKRPTSAVGYKRPISQYARVAMAMGSHPRYRAENIMFLELDVSPPA
VFEMEFSHDQEQDPRALHMERLMRLDSFLERPSTSKVRKSRSWCQSPQRPPPSTTHASLA
SASLRPATVADHE
Number of residues793
Molecular Weight89425.56
Theoretical pINot Available
GO Classification
Functions
  • ATP binding
  • ATPase activity
  • motor activity
  • microtubule motor activity
Processes
  • organelle transport along microtubule
  • microtubule-based movement
  • blood coagulation
  • antigen processing and presentation of exogenous peptide antigen via MHC class II
  • cytoskeleton-dependent intracellular transport
  • organelle organization
Components
  • primary cilium
  • kinesin complex
  • ciliary tip
  • microtubule
  • cytosol
General FunctionMotor activity
Specific FunctionMicrotubule-based anterograde translocator for membranous organelles.
Pfam Domain Function
Transmembrane RegionsNot Available
GenBank Protein IDNot Available
UniProtKB IDO14782
UniProtKB Entry NameKIF3C_HUMAN
Cellular LocationCytoplasm
Gene sequence
>lcl|BSEQ0019735|Kinesin-like protein KIF3C (KIF3C)
ATGGCCAGTAAGACCAAGGCCAGCGAGGCCCTCAAGGTGGTGGCCCGGTGCCGCCCCCTC
AGCAGGAAGGAGGAGGCTGCTGGTCACGAGCAGATCCTGACCATGGACGTGAAACTGGGC
CAGGTGACCCTGCGGAACCCCCGCGCCGCCCCGGGGGAGCTGCCCAAGACCTTCACCTTT
GACGCCGTGTATGATGCCAGCTCCAAGCAGGCCGACCTGTATGACGAAACCGTGAGGCCC
CTGATAGACTCCGTGCTCCAGGGTTTCAATGGCACGGTGTTTGCCTATGGCCAGACGGGC
ACTGGCAAGACCTATACCATGCAGGGGACCTGGGTGGAGCCCGAGCTGCGCGGGGTCATC
CCGAATGCCTTTGAGCACATCTTCACCCACATCTCCCGCTCCCAGAACCAACAGTACCTG
GTCCGGGCCTCCTATTTGGAGATCTACCAGGAAGAGATTCGAGACCTGCTCTCCAAGGAG
CCGGGCAAGAGGCTAGAGCTGAAAGAGAACCCCGAGACTGGCGTCTACATCAAGGACCTC
TCCTCCTTCGTCACCAAGAATGTCAAGGAGATTGAGCATGTGATGAACCTGGGGAACCAG
ACCCGGGCTGTGGGCAGCACCCACATGAATGAGGTCAGCTCCCGCTCCCATGCCATCTTC
ATCATCACTGTGGAGTGCAGCGAACGTGGCTCTGATGGCCAGGACCACATCCGAGTGGGC
AAGCTCAACCTCGTGGACCTGGCTGGCAGCGAGAGGCAGAACAAGGCAGGCCCCAACACA
GCGGGAGGGGCAGCCACACCATCCTCGGGTGGCGGTGGTGGCGGTGGAGGCAGTGGTGGT
GGTGCTGGTGGAGAGAGGCCTAAGGAAGCCTCCAAAATCAACCTCTCATTATCTGCCCTG
GGCAACGTGATTGCTGCCCTGGCGGGCAACAGGAGCACCCACATTCCCTACCGGGACTCC
AAGCTGACCCGGCTGCTCCAGGACTCCCTGGGGGGGAATGCCAAGACCATCATGGTAGCC
ACACTGGGGCCAGCTTCTCACAGCTACGATGAGAGCCTCTCCACCTTGCGCTTTGCCAAC
CGAGCCAAGAACATCAAGAACAAGCCCCGGGTGAACGAGGACCCCAAGGACACACTGCTG
CGGGAATTCCAAGAGGAGATTGCCCGCCTGAAGGCCCAGCTGGAGAAGAGGGGGATGCTG
GGGAAGCGGCCCCGGAGGAAGAGCAGCCGCAGGAAGAAGGCCGTGTCCGCCCCGCCTGGG
TACCCTGAGGGCCCAGTGATTGAGGCCTGGGTGGCAGAAGAGGAGGATGACAACAACAAC
AACCACCGCCCGCCCCAGCCCATCCTGGAGTCAGCCTTGGAGAAGAACATGGAGAATTAC
CTGCAGGAACAGAAGGAGCGGCTGGAGGAGGAGAAGGCAGCCATCCAGGATGACCGCAGC
CTGGTGAGCGAGGAGAAGCAGAAGCTGCTGGAGGAGAAGGAGAAGATGCTGGAGGACCTG
CGGCGGGAACAGCAGGCCACAGAGCTGCTTGCGGCCAAGTACAAGGCCATGGAGAGCAAG
CTCCTCATCGGGGGCAGGAACATCATGGATCACACCAACGAACAGCAGAAGATGTTGGAA
CTGAAGAGGCAGGAGATTGCCGAGCAGAAACGTCGTGAGCGGGAGATGCAGCAGGAGATG
ATGCTCCGGGACGAGGAGACTATGGAGCTCCGGGGCACCTACACATCCCTGCAGCAGGAG
GTGGAGGTCAAAACCAAGAAACTCAAGAAGCTCTACGCCAAGCTGCAGGCGGTGAAGGCG
GAGATCCAGGACCAGCATGATGAGTATATCCGCGTGCGGCAGGACCTGGAGGAGGCGCAG
AACGAGCAGACCCGCGAACTCAAGCTCAAGTACCTAATCATCGAGAACTTCATCCCGCCG
GAGGAGAAGAACAAGATCATGAACCGGCTTTTCCTGGACTGTGAGGAGGAGCAGTGGAAG
TTCCAGCCACTGGTGCCAGCCGGCGTCAGTAGCAGCCAGATGAAGAAGCGGCCAACATCT
GCAGTGGGCTACAAGAGGCCTATCAGCCAGTATGCTCGGGTTGCCATGGCAATGGGGTCC
CACCCCAGGTACAGGGCTGAAAACATAATGTTTCTGGAGTTGGATGTGTCCCCTCCAGCT
GTCTTTGAGATGGAATTCTCTCACGACCAAGAACAAGACCCTCGTGCGCTACACATGGAG
AGGCTCATGCGATTGGACAGCTTTCTGGAAAGACCTTCCACGTCTAAAGTCCGAAAGTCC
AGATCCTGGTGCCAGAGTCCTCAGCGGCCTCCACCTTCCACCACACATGCCTCCCTGGCC
TCTGCTTCTCTGCGCCCTGCAACAGTGGCGGACCATGAGTGA
GenBank Gene IDNot Available
GeneCard IDNot Available
GenAtlas IDNot Available
HGNC IDHGNC:6321
Chromosome Location2
LocusNot Available
References
  1. Sardella M, Navone F, Rocchi M, Rubartelli A, Viggiano L, Vignali G, Consalez GG, Sitia R, Cabibbo A: KIF3C, a novel member of the kinesin superfamily: sequence, expression, and mapping to human chromosome 2 at 2p23. Genomics. 1998 Feb 1;47(3):405-8. 9480755
  2. Telford EA, Wightman P, Leek J, Markham AF, Lench NJ, Bonthron DT: cDNA cloning, genomic organization, and chromosomal localization of a novel human gene that encodes a kinesin-related protein highly similar to mouse Kif3C. Biochem Biophys Res Commun. 1998 Jan 14;242(2):407-12. 9446808
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