2-methylcitrate synthase
| Name | 2-methylcitrate synthase |
|---|---|
| Synonyms |
|
| Gene Name | gltA |
| Organism | Antarctic bacterium DS2-3R |
| Amino acid sequence | >lcl|BSEQ0016866|2-methylcitrate synthase MTEPTIHKGLAGVTADVTAISKVNSDTNSLLYRGYPVQELAAKCSFEQVAYLLWNSELPN DSELKAFVNFERSHRKLDENVKGAIDLLSTACHPMDVARTAVSVLGANHARAQDSSPEAN LEKAMSLLATFPSVVAYDQRRRRGEELIEPREDLDYSANFLWMTFGEEAAPEVVEAFNVS MILYAEHSFNASTFTARVITSTLADLHSAVTGAIGALKGPLHGGANEAVMHTFEEIGIRK DESLDEAATRSKAWMVDALAQKKKVMGFGHRVYKNGDSRVPTMKSALDAMIKHYDRPEML GLYNGLEAAMEEAKQIKPNLDYPAGPTYNLMGFDTEMFTPLFIAARITGWTAHIMEQVAD NALIRPLSEYNGPEQRQVP |
| Number of residues | 379 |
| Molecular Weight | 41832.0 |
| Theoretical pI | 5.17 |
| GO Classification | Functions
Processes
Components
|
| General Function | Citrate synthase activity |
| Specific Function | Involved in the catabolism of short chain fatty acids (SCFA) via the tricarboxylic acid (TCA)(acetyl degradation route) and via the 2-methylcitrate cycle I (propionate degradation route). Catalyzes the Claisen condensation of propionyl-CoA and oxaloacetate (OAA) to yield (2S,3S)-2-methylcitrate (2-MC) and CoA. Also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity. |
| Pfam Domain Function |
|
| Transmembrane Regions | Not Available |
| GenBank Protein ID | Not Available |
| UniProtKB ID | O34002 |
| UniProtKB Entry Name | PRPC_ABDS2 |
| Cellular Location | Not Available |
| Gene sequence | >lcl|BSEQ0005275|1140 bp ATGACCGAACCAACAATTCATAAGGGCCTTGCCGGCGTCACGGCGGATGTCACCGCCATT TCGAAGGTCAATTCTGATACCAACTCGCTGCTGTACCGTGGATACCCCGTTCAGGAACTG GCTGCTAAGTGCAGCTTTGAACAGGTGGCCTACTTGCTGTGGAACAGCGAACTGCCCAAC GATTCCGAGCTGAAAGCTTTCGTAAATTTCGAACGCTCCCACCGGAAACTGGATGAGAAC GTCAAAGGGGCAATAGACCTCCTCTCCACTGCCTGTCACCCTATGGACGTTGCGCGGACC GCCGTCTCAGTTCTGGGAGCCAACCACGCCAGGGCGCAGGATTCCTCCCCGGAAGCAAAT CTAGAAAAGGCGATGTCGCTGCTGGCAACCTTCCCGTCCGTCGTCGCCTACGACCAAAGG CGACGACGCGGTGAGGAACTTATCGAACCACGAGAGGATCTCGATTACTCCGCGAACTTC CTGTGGATGACTTTTGGCGAAGAGGCAGCGCCGGAGGTTGTGGAAGCCTTCAACGTCTCC ATGATTCTCTACGCGGAGCATTCCTTCAACGCCTCGACGTTCACGGCCCGGGTCATCACC TCCACCCTGGCGGATCTGCATTCGGCGGTGACCGGAGCCATAGGTGCCCTCAAGGGGCCG CTGCACGGGGGTGCCAACGAGGCCGTGATGCATACCTTTGAGGAGATTGGGATCCGCAAG GACGAATCCCTCGATGAGGCAGCCACGCGTTCGAAAGCTTGGATGGTCGATGCCCTTGCG CAGAAGAAAAAGGTCATGGGTTTTGGGCACCGCGTGTACAAGAATGGTGACTCCCGGGTC CCCACCATGAAGAGCGCTCTGGACGCCATGATCAAACATTATGATCGTCCGGAAATGCTC GGCCTGTACAACGGACTCGAAGCCGCTATGGAAGAGGCCAAGCAGATCAAGCCGAATCTC GACTACCCGGCAGGACCCACCTATAACCTGATGGGCTTTGACACGGAGATGTTCACTCCG CTCTTCATCGCCGCGCGCATCACCGGTTGGACCGCCCATATCATGGAACAAGTGGCGGAC AACGCTCTGATCCGCCCACTCAGCGAATATAACGGTCCTGAGCAGCGCCAGGTCCCCTGA |
| GenBank Gene ID | U85944 |
| GeneCard ID | Not Available |
| GenAtlas ID | Not Available |
| HGNC ID | Not Available |
| Chromosome Location | Not Available |
| Locus | Not Available |
| References |
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