NameKinesin heavy chain isoform 5C
Synonyms
  • KIAA0531
  • Kinesin heavy chain neuron-specific 2
  • NKHC2
Gene NameKIF5C
OrganismHuman
Amino acid sequence
>lcl|BSEQ0009165|Kinesin heavy chain isoform 5C
MADPAECSIKVMCRFRPLNEAEILRGDKFIPKFKGDETVVIGQGKPYVFDRVLPPNTTQE
QVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIAHDIFDHI
YSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLAVHEDKNRVPYVKGCTERFVSSPEEV
MDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKKLSGKLYLVDLAGSEKVS
KTGAEGAVLDEAKNINKSLSALGNVISALAEGTKTHVPYRDSKMTRILQDSLGGNCRTTI
VICCSPSVFNEAETKSTLMFGQRAKTIKNTVSVNLELTAEEWKKKYEKEKEKNKTLKNVI
QHLEMELNRWRNGEAVPEDEQISAKDQKNLEPCDNTPIIDNIAPVVAGISTEEKEKYDEE
ISSLYRQLDDKDDEINQQSQLAEKLKQQMLDQDELLASTRRDYEKIQEELTRLQIENEAA
KDEVKEVLQALEELAVNYDQKSQEVEDKTRANEQLTDELAQKTTTLTTTQRELSQLQELS
NHQKKRATEILNLLLKDLGEIGGIIGTNDVKTLADVNGVIEEEFTMARLYISKMKSEVKS
LVNRSKQLESAQMDSNRKMNASERELAACQLLISQHEAKIKSLTDYMQNMEQKRRQLEES
QDSLSEELAKLRAQEKMHEVSFQDKEKEHLTRLQDAEEMKKALEQQMESHREAHQKQLSR
LRDEIEEKQKIIDEIRDLNQKLQLEQEKLSSDYNKLKIEDQEREMKLEKLLLLNDKREQA
REDLKGLEETVSRELQTLHNLRKLFVQDLTTRVKKSVELDNDDGGGSAAQKQKISFLENN
LEQLTKVHKQLVRDNADLRCELPKLEKRLRATAERVKALESALKEAKENAMRDRKRYQQE
VDRIKEAVRAKNMARRAHSAQIAKPIRPGHYPASSPTAVHAIRGGGGSSSNSTHYQK
Number of residues957
Molecular Weight109494.01
Theoretical pINot Available
GO Classification
Functions
  • microtubule motor activity
  • ATP-dependent microtubule motor activity, plus-end-directed
  • ATP binding
Processes
  • axon guidance
  • cytoskeleton-dependent intracellular transport
  • organelle organization
  • protein localization
  • mRNA transport
  • microtubule-based movement
Components
  • microtubule
  • kinesin complex
  • cytoplasm
General FunctionMicrotubule motor activity
Specific FunctionMediates dendritic trafficking of mRNAs (By similarity). Kinesin is a microtubule-associated force-producing protein that may play a role in organelle transport.
Pfam Domain Function
Transmembrane RegionsNot Available
GenBank Protein IDNot Available
UniProtKB IDO60282
UniProtKB Entry NameKIF5C_HUMAN
Cellular LocationCytoplasm
Gene sequence
>lcl|BSEQ0013647|Kinesin heavy chain isoform 5C (KIF5C)
ATGGCGGATCCAGCCGAATGCAGCATCAAAGTGATGTGCCGGTTCCGGCCCCTCAACGAA
GCGGAGATCCTCCGCGGGGACAAATTCATCCCCAAATTTAAAGGCGATGAGACCGTGGTG
ATCGGGCAAGGGAAGCCATATGTCTTCGACAGAGTGCTACCTCCCAACACGACCCAAGAG
CAGGTTTACAATGCATGTGCGAAGCAAATTGTCAAAGATGTCCTTGAAGGTTATAACGGG
ACGATTTTTGCGTATGGGCAGACTTCATCAGGAAAAACCCACACCATGGAGGGGAAGCTG
CATGACCCCCAGCTCATGGGGATCATCCCACGAATTGCCCATGATATCTTTGACCATATC
TACTCCATGGATGAGAACCTGGAGTTTCACATAAAGGTTTCCTATTTTGAGATCTACTTG
GACAAAATAAGGGACTTACTTGATGTATCCAAGACCAACTTGGCTGTTCATGAAGATAAA
AACAGAGTCCCGTATGTAAAGGGGTGCACTGAGCGGTTTGTGTCGAGCCCTGAGGAAGTC
ATGGATGTAATAGATGAAGGCAAAGCAAACCGACACGTGGCTGTGACAAACATGAATGAA
CACAGCTCTAGAAGTCACAGTATCTTCCTGATAAATATTAAACAAGAGAATGTAGAGACT
GAAAAAAAACTCAGTGGGAAACTTTATTTGGTTGATTTGGCTGGGAGCGAAAAGGTCAGC
AAAACTGGTGCCGAGGGAGCTGTTCTTGACGAAGCTAAAAATATCAATAAGTCTTTGTCT
GCTCTTGGAAATGTGATCTCTGCTTTGGCAGAAGGGACAAAAACACATGTGCCATACCGG
GACAGCAAGATGACTCGGATTCTTCAGGACTCTTTGGGTGGGAACTGCAGAACCACCATC
GTCATTTGCTGTTCTCCTTCTGTCTTCAATGAGGCTGAGACCAAGTCCACACTGATGTTC
GGACAGAGAGCTAAGACCATCAAGAATACAGTCTCTGTGAACCTAGAACTGACAGCAGAA
GAATGGAAGAAGAAATATGAAAAAGAGAAAGAGAAAAACAAGACTTTGAAGAATGTTATC
CAGCATCTGGAGATGGAGCTAAACAGGTGGAGGAATGGAGAAGCTGTGCCTGAGGATGAA
CAGATCAGTGCCAAGGACCAGAAGAACCTGGAGCCTTGTGATAACACCCCCATCATAGAC
AATATTGCTCCTGTTGTTGCTGGCATCTCTACAGAGGAGAAAGAGAAGTACGATGAGGAG
ATCTCCAGTCTCTACAGACAACTGGATGACAAGGATGATGAAATTAACCAGCAGAGCCAG
CTGGCTGAAAAGCTGAAGCAACAGATGTTGGATCAGGATGAGCTTTTAGCTTCCACAAGA
AGAGACTATGAGAAGATACAGGAGGAGCTGACACGTCTCCAGATTGAAAATGAGGCAGCC
AAGGATGAGGTGAAAGAAGTTCTCCAGGCCCTGGAGGAGCTGGCTGTCAATTATGACCAG
AAATCACAGGAAGTGGAGGATAAGACCCGGGCCAATGAGCAGCTGACAGACGAGCTGGCC
CAGAAAACGACTACATTGACAACCACACAGAGAGAGCTGAGCCAGCTACAAGAGCTTAGC
AACCACCAGAAGAAAAGGGCAACTGAGATCCTGAATTTGCTGTTGAAAGATCTGGGGGAG
ATAGGTGGAATTATTGGCACCAATGATGTGAAAACTTTGGCAGATGTGAATGGAGTCATT
GAGGAGGAGTTTACCATGGCCCGCCTGTACATCAGCAAGATGAAGTCAGAGGTCAAGTCC
CTGGTGAACCGCAGCAAACAGCTCGAGAGCGCCCAGATGGACTCCAACAGGAAGATGAAT
GCCAGCGAGCGGGAGCTGGCAGCCTGCCAGCTGCTCATCTCCCAGCACGAAGCCAAGATC
AAGTCTCTGACAGACTACATGCAGAACATGGAACAGAAGAGGAGGCAGCTAGAAGAGTCC
CAGGACTCGCTCAGCGAAGAGCTGGCAAAGCTCCGAGCCCAGGAAAAAATGCACGAAGTC
AGCTTCCAGGATAAGGAGAAGGAACATCTGACGCGGTTGCAGGATGCTGAAGAAATGAAG
AAGGCGCTGGAGCAGCAGATGGAGAGCCACCGGGAAGCTCACCAGAAGCAGCTGTCCAGA
CTCCGAGACGAAATTGAGGAGAAGCAGAAAATCATTGATGAGATTCGGGATTTGAATCAG
AAACTGCAACTGGAACAGGAGAAGCTTAGTTCTGATTATAACAAGCTGAAAATAGAGGAC
CAAGAGAGAGAAATGAAGCTGGAAAAGCTCTTATTGCTCAACGATAAAAGGGAACAAGCC
AGAGAAGACCTCAAAGGGCTGGAGGAGACAGTGTCTAGAGAATTGCAGACACTGCACAAC
CTTCGGAAACTCTTTGTCCAGGATCTGACCACCCGAGTTAAAAAAAGTGTGGAGTTGGAC
AACGATGATGGAGGGGGCAGTGCTGCCCAGAAGCAGAAAATTTCCTTCTTGGAGAATAAC
CTGGAGCAGCTCACCAAAGTTCACAAGCAGCTGGTCCGGGACAACGCAGACCTGCGCTGT
GAACTGCCCAAGCTGGAGAAGCGGCTGCGTGCCACGGCGGAGCGCGTCAAGGCTCTGGAG
AGCGCGCTGAAGGAGGCCAAGGAGAACGCCATGCGGGACCGTAAGCGCTACCAGCAGGAG
GTGGATCGTATCAAGGAGGCCGTGCGGGCCAAGAACATGGCCAGAAGGGCCCATTCAGCC
CAGATCGCCAAGCCCATCCGCCCCGGACACTACCCGGCCTCATCTCCAACGGCCGTCCAT
GCCATTCGAGGGGGAGGAGGCAGCTCTTCAAATTCCACTCACTACCAGAAATAA
GenBank Gene IDNot Available
GeneCard IDNot Available
GenAtlas IDNot Available
HGNC IDHGNC:6325
Chromosome Location2
LocusNot Available
References
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