Transcription termination/antitermination protein NusG

NameTranscription termination/antitermination protein NusG
SynonymsNot Available
Gene NamenusG
OrganismAquifex aeolicus (strain VF5)
Amino acid sequence
>lcl|BSEQ0011920|Transcription termination/antitermination protein NusG
MSEQQVQELEKKWYALQVEPGKENEAKENLLKVLELEGLKDLVDEVIVPAEEKVVIRAQG
KEKYRLSLKGNARDISVLGKKGVTTFRIENGEVKVVESVEGDTCVNAPPISKPGQKITCK
ENKTEAKIVLDNKIFPGYILIKAHMNDKLLMAIEKTPHVFRPVMVGGKPVPLKEEEVQNI
LNQIKRGVKPSKVEFEKGDQVRVIEGPFMNFTGTVEEVHPEKRKLTVMISIFGRMTPVEL
DFDQVEKI
Number of residues248
Molecular Weight27998.575
Theoretical pI7.51
GO Classification
Processes
  • DNA-templated transcription, termination
  • transcription antitermination
  • DNA-templated transcription, elongation
  • regulation of DNA-templated transcription, elongation
General FunctionNot Available
Specific FunctionParticipates in transcription elongation, termination and antitermination.
Pfam Domain Function
Transmembrane RegionsNot Available
GenBank Protein IDNot Available
UniProtKB IDO67757
UniProtKB Entry NameNUSG_AQUAE
Cellular LocationNot Available
Gene sequence
>lcl|BSEQ0011921|Transcription termination/antitermination protein NusG (nusG)
ATGAGCGAGCAACAGGTTCAGGAACTTGAGAAAAAGTGGTACGCACTGCAGGTAGAGCCC
GGAAAAGAGAACGAAGCTAAGGAAAACTTACTGAAAGTTCTGGAACTGGAAGGTTTAAAG
GACCTCGTTGACGAGGTAATAGTTCCCGCAGAGGAAAAGGTAGTCATAAGGGCTCAGGGC
AAGGAAAAGTACAGGCTCTCTCTCAAGGGAAACGCGAGGGACATATCCGTTTTAGGGAAG
AAAGGTGTTACCACATTCAGGATAGAGAACGGAGAAGTTAAGGTCGTTGAGAGTGTTGAA
GGAGACACTTGCGTAAACGCCCCTCCCATATCAAAACCCGGACAAAAGATCACGTGTAAG
GAAAATAAAACGGAAGCAAAGATAGTTCTGGATAACAAAATATTTCCCGGATACATACTC
ATAAAGGCTCACATGAACGACAAGCTCCTCATGGCTATTGAGAAAACTCCCCACGTCTTC
AGACCTGTAATGGTGGGCGGAAAGCCCGTTCCTCTGAAAGAGGAAGAGGTTCAAAACATT
CTCAATCAAATAAAGAGGGGTGTTAAACCTTCCAAGGTTGAGTTTGAAAAAGGAGATCAG
GTAAGGGTTATAGAAGGACCGTTTATGAACTTTACGGGAACTGTTGAGGAAGTTCATCCC
GAGAAGAGGAAATTAACTGTTATGATAAGTATTTTCGGAAGGATGACTCCGGTAGAACTG
GACTTTGACCAAGTGGAAAAGATTTGA
GenBank Gene IDAE000657
GeneCard IDNot Available
GenAtlas IDNot Available
HGNC IDNot Available
Chromosome LocationNot Available
LocusNot Available
References
  1. Deckert G, Warren PV, Gaasterland T, Young WG, Lenox AL, Graham DE, Overbeek R, Snead MA, Keller M, Aujay M, Huber R, Feldman RA, Short JM, Olsen GJ, Swanson RV: The complete genome of the hyperthermophilic bacterium Aquifex aeolicus. Nature. 1998 Mar 26;392(6674):353-8. 9537320
  2. Steiner T, Kaiser JT, Marinkovic S, Huber R, Wahl MC: Crystal structures of transcription factor NusG in light of its nucleic acid- and protein-binding activities. EMBO J. 2002 Sep 2;21(17):4641-53. 12198166
  3. Knowlton JR, Bubunenko M, Andrykovitch M, Guo W, Routzahn KM, Waugh DS, Court DL, Ji X: A spring-loaded state of NusG in its functional cycle is suggested by X-ray crystallography and supported by site-directed mutants. Biochemistry. 2003 Mar 4;42(8):2275-81. 12600194