Endolysin
| Name | Endolysin |
|---|---|
| Synonyms |
|
| Gene Name | R |
| Organism | Enterobacteria phage lambda |
| Amino acid sequence | >lcl|BSEQ0016637|Endolysin MVEINNQRKAFLDMLAWSEGTDNGRQKTRNHGYDVIVGGELFTDYSDHPRKLVTLNPKLK STGAGRYQLLSRWWDAYRKQLGLKDFSPKSQDAVALQQIKERGALPMIDRGDIRQAIDRC SNIWASLPGAGYGQFEHKADSLIAKFKEAGGTVREIDV |
| Number of residues | 158 |
| Molecular Weight | 17825.045 |
| Theoretical pI | 9.66 |
| GO Classification | Functions
Processes
Components
|
| General Function | Lysozyme activity |
| Specific Function | Endolysin with transglycosylase activity that degrades host peptidoglycans and participates with the holin and spanin proteins in the sequential events which lead to the programmed host cell lysis releasing the mature viral particles. Once the holin has permeabilized the host cell membrane, the endolysin can reach the periplasm and break down the peptidoglycan layer. |
| Pfam Domain Function |
|
| Transmembrane Regions | Not Available |
| GenBank Protein ID | 215163 |
| UniProtKB ID | P03706 |
| UniProtKB Entry Name | ENLYS_LAMBD |
| Cellular Location | Host cytoplasm |
| Gene sequence | >lcl|BSEQ0016638|Endolysin (R) ATGGTAGAAATCAATAATCAACGTAAGGCGTTCCTCGATATGCTGGCGTGGTCGGAGGGA ACTGATAACGGACGTCAGAAAACCAGAAATCATGGTTATGACGTCATTGTAGGCGGAGAG CTATTTACTGATTACTCCGATCACCCTCGCAAACTTGTCACGCTAAACCCAAAACTCAAA TCAACAGGCGCCGGACGCTACCAGCTTCTTTCCCGTTGGTGGGATGCCTACCGCAAGCAG CTTGGCCTGAAAGACTTCTCTCCGAAAAGTCAGGACGCTGTGGCATTGCAGCAGATTAAG GAGCGTGGCGCTTTACCTATGATTGATCGTGGTGATATCCGTCAGGCAATCGACCGTTGC AGCAATATCTGGGCTTCACTGCCGGGCGCTGGTTATGGTCAGTTCGAGCATAAGGCTGAC AGCCTGATTGCAAAATTCAAAGAAGCGGGCGGAACGGTCAGAGAGATTGATGTATGA |
| GenBank Gene ID | J02459 |
| GeneCard ID | Not Available |
| GenAtlas ID | Not Available |
| HGNC ID | Not Available |
| Chromosome Location | Not Available |
| Locus | Not Available |
| References |
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