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Semenogelin-1
Name | Semenogelin-1 |
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Synonyms |
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Gene Name | SEMG1 |
Organism | Human |
Amino acid sequence | >lcl|BSEQ0009862|Semenogelin-1 MKPNIIFVLSLLLILEKQAAVMGQKGGSKGRLPSEFSQFPHGQKGQHYSGQKGKQQTESK GSFSIQYTYHVDANDHDQSRKSQQYDLNALHKTTKSQRHLGGSQQLLHNKQEGRDHDKSK GHFHRVVIHHKGGKAHRGTQNPSQDQGNSPSGKGISSQYSNTEERLWVHGLSKEQTSVSG AQKGRKQGGSQSSYVLQTEELVANKQQRETKNSHQNKGHYQNVVEVREEHSSKVQTSLCP AHQDKLQHGSKDIFSTQDELLVYNKNQHQTKNLNQDQQHGRKANKISYQSSSTEERRLHY GENGVQKDVSQSSIYSQTEEKAQGKSQKQITIPSQEQEHSQKANKISYQSSSTEERRLHY GENGVQKDVSQRSIYSQTEKLVAGKSQIQAPNPKQEPWHGENAKGESGQSTNREQDLLSH EQKGRHQHGSHGGLDIVIIEQEDDSDRHLAQHLNNDRNPLFT |
Number of residues | 462 |
Molecular Weight | 52130.885 |
Theoretical pI | Not Available |
GO Classification | Functions
Processes
Components
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General Function | Structural molecule activity |
Specific Function | Predominant protein in semen. It participates in the formation of a gel matrix entrapping the accessory gland secretions and ejaculated spermatozoa. Fragments of semenogelin and/or fragments of the related proteins may contribute to the activation of progressive sperm movements as the gel-forming proteins are fragmented by KLK3/PSA.Alpha-inhibin-92 and alpha-inhibin-31, derived from the proteolytic degradation of semenogelin, inhibit the secretion of pituitary follicle-stimulating hormone. |
Pfam Domain Function |
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Transmembrane Regions | Not Available |
GenBank Protein ID | Not Available |
UniProtKB ID | P04279 |
UniProtKB Entry Name | SEMG1_HUMAN |
Cellular Location | Secreted |
Gene sequence | >lcl|BSEQ0020903|Semenogelin-1 (SEMG1) ATGAAGCCCAACATCATCTTTGTACTTTCCCTGCTCCTCATCTTGGAGAAGCAAGCAGCT GTGATGGGACAAAAAGGTGGATCAAAAGGCCGATTACCAAGTGAATTTTCCCAATTTCCA CACGGACAAAAGGGCCAGCACTATTCTGGACAAAAAGGCAAGCAACAAACTGAATCCAAA GGCAGTTTTTCTATTCAATACACATATCATGTAGATGCCAATGATCATGACCAGTCCCGA AAAAGTCAGCAATATGATTTGAATGCCCTACATAAGACGACAAAATCACAACGACATCTA GGTGGAAGTCAACAACTGCTCCATAATAAACAAGAAGGCAGAGACCATGATAAATCAAAA GGTCATTTTCACAGGGTAGTTATACACCATAAAGGAGGCAAAGCTCATCGTGGGACACAA AATCCTTCTCAAGATCAGGGGAATAGCCCATCTGGAAAGGGAATATCCAGTCAATATTCA AACACAGAAGAAAGGCTGTGGGTTCATGGACTAAGTAAAGAACAAACTTCCGTCTCTGGT GCACAAAAAGGTAGAAAACAAGGCGGATCCCAAAGCAGTTATGTTCTCCAAACTGAAGAG CTAGTAGCTAACAAACAACAACGTGAGACTAAAAATTCTCATCAAAATAAAGGGCATTAC CAAAATGTGGTTGAAGTGAGAGAGGAACATTCAAGTAAAGTACAAACCTCACTCTGTCCT GCGCACCAAGACAAACTCCAACATGGATCCAAAGACATTTTTTCTACCCAAGATGAGCTC CTAGTATATAACAAGAATCAACACCAGACAAAAAATCTCAATCAAGATCAACAGCATGGC CGAAAGGCAAATAAAATATCATACCAATCTTCAAGTACAGAAGAAAGACGACTCCACTAT GGAGAAAATGGTGTGCAGAAAGATGTATCCCAAAGCAGTATTTATAGCCAAACTGAAGAG AAAGCACAGGGCAAGTCTCAAAAACAGATAACAATTCCCAGTCAAGAGCAAGAGCATAGC CAAAAGGCAAATAAAATATCATACCAATCTTCAAGTACGGAAGAAAGACGACTCCACTAT GGAGAAAATGGTGTGCAGAAAGATGTATCCCAACGCAGTATTTATAGCCAAACTGAAAAG CTAGTAGCAGGCAAGTCTCAAATCCAGGCACCAAATCCTAAGCAAGAGCCATGGCATGGT GAAAATGCAAAAGGAGAGTCTGGCCAATCTACAAATAGAGAACAAGACCTACTCAGTCAT GAACAAAAAGGCAGACACCAACATGGATCTCATGGGGGATTGGATATTGTAATTATAGAG CAGGAAGATGACAGTGATCGTCATTTGGCACAACATCTTAACAACGACCGAAACCCATTA TTTACATAA |
GenBank Gene ID | Not Available |
GeneCard ID | Not Available |
GenAtlas ID | Not Available |
HGNC ID | HGNC:10742 |
Chromosome Location | 20 |
Locus | Not Available |
References |
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