NameCytochrome b-c1 complex subunit 6, mitochondrial
Synonyms
  • Complex III subunit 6
  • Complex III subunit VIII
  • Cytochrome c1 non-heme 11 kDa protein
  • Mitochondrial hinge protein
  • Ubiquinol-cytochrome c reductase complex 11 kDa protein
Gene NameUQCRH
OrganismHuman
Amino acid sequence
>lcl|BSEQ0012689|Cytochrome b-c1 complex subunit 6, mitochondrial
MGLEDEQKMLTESGDPEEEEEEEEELVDPLTTVREQCEQLEKCVKARERLELCDERVSSR
SHTEEDCTEELFDFLHARDHCVAHKLFNNLK
Number of residues91
Molecular Weight10738.68
Theoretical pI4.1
GO Classification
Functions
  • ubiquinol-cytochrome-c reductase activity
Processes
  • aerobic respiration
  • mitochondrial electron transport, ubiquinol to cytochrome c
  • small molecule metabolic process
  • cellular metabolic process
  • oxidation-reduction process
  • respiratory electron transport chain
  • hydrogen ion transmembrane transport
  • oxidative phosphorylation
Components
  • mitochondrion
  • mitochondrial inner membrane
  • mitochondrial respiratory chain
General FunctionUbiquinol-cytochrome-c reductase activity
Specific FunctionThis is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This protein may mediate formation of the complex between cytochromes c and c1.
Pfam Domain Function
Transmembrane RegionsNot Available
GenBank Protein ID188565
UniProtKB IDP07919
UniProtKB Entry NameQCR6_HUMAN
Cellular LocationMitochondrion inner membrane
Gene sequence
>lcl|BSEQ0007388|276 bp
ATGGGACTGGAGGACGAGCAAAAGATGCTTACCGAATCCGGAGATCCTGAGGAGGAGGAA
GAGGAAGAGGAGGAATTAGTGGATCCCCTAACAACAGTGAGAGAGCAATGCGAGCAGTTG
GAGAAATGTGTAAAGGCCCGGGAGCGGCTAGAGCTCTGTGATGAGCGTGATTCCTCTCGA
TCACATACAGAAGAGGATTGCACGGAGGAGCTCTTTGACTTCTTGCATGCGAGGGACCAT
TGCGTGGCCCACAAACTCTTTAACAACTTGAAATAA
GenBank Gene IDM36647
GeneCard IDNot Available
GenAtlas IDNot Available
HGNC IDHGNC:12590
Chromosome LocationNot Available
Locus1p34.1
References
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