Aspartate 1-decarboxylase

NameAspartate 1-decarboxylase
Synonyms
  • 4.1.1.11
  • Aspartate alpha-decarboxylase
Gene NamepanD
OrganismShigella flexneri
Amino acid sequence
>lcl|BSEQ0011068|Aspartate 1-decarboxylase
MIRTMLQGKLHRVKVTHADLHYEGSCAIDQDFLDAAGILENEAIDIWNVTNGKRFSTYAI
AAERGSRIISVNGAAAHCASVGDIVIIASFVTMPDEEARTWRPNVAYFEGDNEMKRTAKA
IPVQVA
Number of residues126
Molecular Weight13833.595
Theoretical pI6.09
GO Classification
Functions
  • aspartate 1-decarboxylase activity
Processes
  • alanine biosynthetic process
  • pantothenate biosynthetic process
Components
  • cytoplasm
General FunctionAspartate 1-decarboxylase activity
Specific FunctionCatalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
Pfam Domain Function
Transmembrane RegionsNot Available
GenBank Protein ID24050337
UniProtKB IDP0A793
UniProtKB Entry NamePAND_SHIFL
Cellular LocationCytoplasm
Gene sequence
>lcl|BSEQ0011069|Aspartate 1-decarboxylase (panD)
ATGATTCGCACGATGCTGCAGGGCAAACTCCACCGCGTGAAAGTGACTCATGCGGACCTG
CACTATGAAGGTTCTTGCGCCATTGACCAGGATTTTCTTGACGCAGCCGGTATTCTCGAA
AACGAAGCCATCGATATCTGGAATGTCACCAACGGCAAGCGTTTCTCCACTTATGCCATC
GCGGCAGAACGCGGTTCGAGAATTATTTCTGTTAACGGTGCGGCGGCCCACTGCGCCAGC
GTCGGCGATATTGTCATCATCGCCAGCTTCGTTACCATGCCAGATGAAGAAGCTCGCACC
TGGCGACCCAATGTCGCCTATTTTGAAGGCGACAATGAAATGAAACGTACCGCGAAAGCG
ATTCCGGTACAGGTTGCTTGA
GenBank Gene IDAE005674
GeneCard IDNot Available
GenAtlas IDNot Available
HGNC IDNot Available
Chromosome LocationNot Available
LocusNot Available
References
  1. Jin Q, Yuan Z, Xu J, Wang Y, Shen Y, Lu W, Wang J, Liu H, Yang J, Yang F, Zhang X, Zhang J, Yang G, Wu H, Qu D, Dong J, Sun L, Xue Y, Zhao A, Gao Y, Zhu J, Kan B, Ding K, Chen S, Cheng H, Yao Z, He B, Chen R, Ma D, Qiang B, Wen Y, Hou Y, Yu J: Genome sequence of Shigella flexneri 2a: insights into pathogenicity through comparison with genomes of Escherichia coli K12 and O157. Nucleic Acids Res. 2002 Oct 15;30(20):4432-41. 12384590
  2. Wei J, Goldberg MB, Burland V, Venkatesan MM, Deng W, Fournier G, Mayhew GF, Plunkett G 3rd, Rose DJ, Darling A, Mau B, Perna NT, Payne SM, Runyen-Janecky LJ, Zhou S, Schwartz DC, Blattner FR: Complete genome sequence and comparative genomics of Shigella flexneri serotype 2a strain 2457T. Infect Immun. 2003 May;71(5):2775-86. 12704152