NameSolute carrier family 2, facilitated glucose transporter member 5
Synonyms
  • Fructose transporter
  • Glucose transporter type 5, small intestine
  • GLUT-5
  • GLUT5
Gene NameSLC2A5
OrganismHuman
Amino acid sequence
>lcl|BSEQ0008980|Solute carrier family 2, facilitated glucose transporter member 5
MEQQDQSMKEGRLTLVLALATLIAAFGSSFQYGYNVAAVNSPALLMQQFYNETYYGRTGE
FMEDFPLTLLWSVTVSMFPFGGFIGSLLVGPLVNKFGRKGALLFNNIFSIVPAILMGCSR
VATSFELIIISRLLVGICAGVSSNVVPMYLGELAPKNLRGALGVVPQLFITVGILVAQIF
GLRNLLANVDGWPILLGLTGVPAALQLLLLPFFPESPRYLLIQKKDEAAAKKALQTLRGW
DSVDREVAEIRQEDEAEKAAGFISVLKLFRMRSLRWQLLSIIVLMGGQQLSGVNAIYYYA
DQIYLSAGVPEEHVQYVTAGTGAVNVVMTFCAVFVVELLGRRLLLLLGFSICLIACCVLT
AALALQDTVSWMPYISIVCVISYVIGHALGPSPIPALLITEIFLQSSRPSAFMVGGSVHW
LSNFTVGLIFPFIQEGLGPYSFIVFAVICLLTTIYIFLIVPETKAKTFIEINQIFTKMNK
VSEVYPEKEELKELPPVTSEQ
Number of residues501
Molecular Weight54973.42
Theoretical pINot Available
GO Classification
Functions
  • glucose transmembrane transporter activity
  • fructose transmembrane transporter activity
Processes
  • glucose transmembrane transport
  • cellular response to fructose stimulus
  • small molecule metabolic process
  • carbohydrate metabolic process
  • transmembrane transport
  • glucose transport
  • fructose transport
  • hexose transport
Components
  • plasma membrane
  • integral component of membrane
  • extracellular exosome
  • apical plasma membrane
General FunctionGlucose transmembrane transporter activity
Specific FunctionCytochalasin B-sensitive carrier. Seems to function primarily as a fructose transporter.
Pfam Domain Function
Transmembrane Regions13-33 69-89 99-119 121-141 162-182 193-213 278-298 319-339 343-363 369-389 413-433 440-460
GenBank Protein IDNot Available
UniProtKB IDP22732
UniProtKB Entry NameGTR5_HUMAN
Cellular LocationApical cell membrane
Gene sequence
>lcl|BSEQ0017662|Solute carrier family 2, facilitated glucose transporter member 5 (SLC2A5)
ATGGAGCAACAGGATCAGAGCATGAAGGAAGGGAGGCTGACGCTTGTGCTTGCCCTGGCA
ACCCTGATAGCTGCCTTTGGGTCATCCTTCCAGTATGGGTACAACGTGGCTGCTGTCAAC
TCCCCAGCACTGCTCATGCAACAATTTTACAATGAGACTTACTATGGTAGGACCGGTGAA
TTCATGGAAGACTTCCCCTTGACGTTGCTGTGGTCTGTAACCGTGTCCATGTTTCCATTT
GGAGGGTTTATCGGATCCCTCCTGGTCGGCCCCTTGGTGAATAAATTTGGCAGAAAAGGG
GCCTTGCTGTTCAACAACATATTTTCTATCGTGCCTGCGATCTTAATGGGATGCAGCAGA
GTCGCCACATCATTTGAGCTTATCATTATTTCCAGACTTTTGGTGGGAATATGTGCAGGT
GTATCTTCCAACGTGGTCCCCATGTACTTAGGGGAGCTGGCCCCTAAAAACCTGCGGGGG
GCTCTCGGGGTGGTGCCCCAGCTCTTCATCACTGTTGGCATCCTTGTGGCCCAGATCTTT
GGTCTTCGGAATCTCCTTGCAAACGTAGATGGTGAGTTCAGGACATCTCGGGAGCACCCC
CACCCCTTCACCACTACCCTTGGCCCCCTCCTTGTGTTCCAAAGCCACCACCACAGGACA
GGACTTTCTGCAGACTGGTCTCTTCTAACAGGCTGGATGTCCTTGGGGGGCCCATCCTGT
CCCGAGCCAACATAG
GenBank Gene IDNot Available
GeneCard IDNot Available
GenAtlas IDNot Available
HGNC IDHGNC:11010
Chromosome Location1
LocusNot Available
References
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