T3DB: Pseudomonalisin

Name	Pseudomonalisin
Synonyms	3.4.21.100 Pepstatin-insensitive carboxyl proteinase Pseudomonapepsin
Gene Name	pcp
Organism	Pseudomonas sp. (strain 101)
Amino acid sequence	>lcl\|BSEQ0011395\|Pseudomonalisin MKSSAAKQTVLCLNRYAVVALPLAIASFAAFGASPASTLWAPTDTKAFVTPAQVEARSAA PLLELAAGETAHIVVSLKLRDEAQLKQLAQAVNQPGNAQFGKFLKRRQFLSQFAPTEAQV QAVVAHLRKNGFVNIHVVPNRLLISADGSAGAVKAAFNTPLVRYQLNGKAGYANTAPAQV PQDLGEIVGSVLGLQNVTRAHPMLKVGERSAAKTLAAGTAKGHNPTEFPTIYDASSAPTA ANTTVGIITIGGVSQTLQDLQQFTSANGLASVNTQTIQTGSSNGDYSDDQQGQGEWDLDS QSIVGSAGGAVQQLLFYMADQSASGNTGLTQAFNQAVSDNVAKVINVSLGWCEADANADG TLQAEDRIFATAAAQGQTFSVSSGDEGVYECNNRGYPDGSTYSVSWPASSPNVIAVGGTT LYTTSAGAYSNETVWNEGLDSNGKLWATGGGYSVYESKPSWQSVVSGTPGRRLLPDISFD AAQGTGALIYNYGQLQQIGGTSLASPIFVGLWARLQSANSNSLGFPAASFYSAISSTPSL VHDVKSGNNGYGGYGYNAGTGWDYPTGWGSLDIAKLSAYIRSNGFGH
Number of residues	587
Molecular Weight	61072.27
Theoretical pI	5.92
GO Classification	Functions serine-type endopeptidase activity metal ion binding Components periplasmic space
General Function	Serine-type endopeptidase activity
Specific Function	Not Available
Pfam Domain Function	Peptidase_S8 (PF00082 ) Pro-kuma_activ (PF09286 )
Transmembrane Regions	Not Available
GenBank Protein ID	688417
UniProtKB ID	P42790
UniProtKB Entry Name	PICP_PSESR
Cellular Location	Periplasm
Gene sequence	>lcl\|BSEQ0003834\|1764 bp ATGAAGTCGTCAGCCGCAAAACAAACGGTCCTGTGTCTAAACCGTTACGCGGTCGTTGCT TTGCCTCTCGCTATTGCTTCGTTCGCTGCGTTCGGCGCATCGCCCGCGTCCACACTGTGG GCGCCCACCGACACGAAGGCGTTTGTAACGCCCGCCCAGGTCGAGGCGCGCAGTGCGGCG CCGTTGCTCGAACTCGCCGCCGGCGAGACCGCGCATATCGTCGTCAGCCTCAAGCTTCGC GACGAGGCGCAACTGAAGCAACTCGCGCAGGCAGTCAACCAGCCGGGCAACGCGCAGTTC GGCAAATTCCTCAAGCGTCGGCAATTCCTCTCGCAATTCGCGCCGACCGAGGCGCAAGTG CAGGCCGTCGTCGCGCATTTACGGAAGAACGGCTTCGTCAACATTCACGTCGTGCCGAAC CGCCTGCTGATTTCCGCCGACGGCAGCGCCGGCGCCGTCAAAGCGGCCTTCAACACGCCG CTGGTTCGCTATCAGCTGAACGGCAAGGCCGGCTACGCGAACACGGCGCCGGCACAGGTG CCGCAGGATCTCGGCGAGATCGTCGGTTCGGTGCTCGGCTTGCAGAACGTCACGCGTGCC CATCCGATGCTGAAGGTCGGCGAGCGTTCCGCCGCGAAGACGCTGGCCGCCGGTACGGCC AAGGGCCACAATCCGACCGAGTTCCCAACGATCTACGACGCCAGCAGCGCGCCCACCGCG GCGAACACGACGGTCGGCATCATCACGATCGGCGGCGTCTCGCAGACGCTTCAGGATCTC CAGCAGTTCACCAGCGCGAATGGCCTTGCGTCCGTCAACACGCAGACGATCCAGACCGGA TCGTCGAATGGCGACTACAGCGACGATCAGCAAGGCCAGGGTGAGTGGGACCTCGACAGC CAGTCGATTGTCGGTTCCGCGGGCGGCGCGGTGCAGCAACTGCTGTTCTACATGGCCGAT CAAAGCGCGTCCGGCAACACCGGCCTCACGCAGGCGTTCAATCAGGCGGTGTCCGATAAC GTCGCGAAGGTGATCAACGTGTCGCTCGGCTGGTGTGAAGCCGATGCCAACGCTGACGGC ACGCTGCAGGCCGAAGATCGCATCTTCGCGACGGCCGCGGCACAAGGGCAAACCTTCTCG GTGTCGTCCGGCGATGAGGGCGTGTACGAATGCAACAACCGCGGCTACCCTGACGGCAGC ACCTATTCGGTATCGTGGCCGGCCTCGTCGCCCAACGTGATCGCCGTCGGCGGCACGACG CTTTACACGACGTCAGCAGGCGCCTACTCGAACGAAACCGTCTGGAACGAAGGGCTCGAC AGCAACGGCAAGCTCTGGGCAACCGGCGGTGGCTACAGCGTGTACGAGTCGAAGCCGTCG TGGCAGTCGGTGGTGAGCGGCACGCCGGGCCGGCGTCTGCTACCCGACATCTCCTTCGAC GCGGCGCAGGGCACGGGCGCACTGATTTACAACTACGGCCAGCTTCAGCAGATCGGCGGG ACGAGCCTCGCTTCGCCAATCTTCGTCGGGCTGTGGGCACGTTTGCAGAGCGCGAATTCG AATAGCCTGGGCTTCCCCGCAGCCAGCTTTTACAGCGCCATTAGCTCGACGCCTTCGCTG GTGCACGACGTGAAATCGGGTAACAACGGCTACGGCGGCTATGGTTACAACGCAGGCACC GGTTGGGACTATCCGACCGGATGGGGAAGCCTCGATATTGCGAAGCTGTCCGCTTATATC AGGAGCAACGGCTTTGGACATTGA
GenBank Gene ID	D37970
GeneCard ID	Not Available
GenAtlas ID	Not Available
HGNC ID	Not Available
Chromosome Location	Not Available
Locus	Not Available
References	Oda K, Takahashi T, Tokuda Y, Shibano Y, Takahashi S: Cloning, nucleotide sequence, and expression of an isovaleryl pepstatin-insensitive carboxyl proteinase gene from Pseudomonas sp. 101. J Biol Chem. 1994 Oct 21;269(42):26518-24. 7929375 Hayashi K, Izu H, Oda K, Fukuhara K, Matsuo M, Takano R, Hara S: The primary structure of pepstatin-insensitive carboxyl proteinase produced by Pseudomonas sp. No. 101. J Biochem. 1995 Oct;118(4):738-44. 8576087 Oyama H, Abe S, Ushiyama S, Takahashi S, Oda K: Identification of catalytic residues of pepstatin-insensitive carboxyl proteinases from prokaryotes by site-directed mutagenesis. J Biol Chem. 1999 Sep 24;274(39):27815-22. 10488127 Wlodawer A, Li M, Gustchina A, Dauter Z, Uchida K, Oyama H, Goldfarb NE, Dunn BM, Oda K: Inhibitor complexes of the Pseudomonas serine-carboxyl proteinase. Biochemistry. 2001 Dec 25;40(51):15602-11. 11747435 Wlodawer A, Li M, Dauter Z, Gustchina A, Uchida K, Oyama H, Dunn BM, Oda K: Carboxyl proteinase from Pseudomonas defines a novel family of subtilisin-like enzymes. Nat Struct Biol. 2001 May;8(5):442-6. 11323721 Wlodawer A, Li M, Gustchina A, Oyama H, Oda K, Beyer BB, Clemente J, Dunn BM: Two inhibitor molecules bound in the active site of Pseudomonas sedolisin: a model for the bi-product complex following cleavage of a peptide substrate. Biochem Biophys Res Commun. 2004 Feb 6;314(2):638-45. 14733955