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NameAcetylcholine-binding protein
  • ACh-binding protein
Gene NameNot Available
OrganismGreat pond snail
Amino acid sequence
>lcl|BSEQ0017679|Acetylcholine-binding protein
Number of residues229
Molecular Weight26061.08
Theoretical pINot Available
GO Classification
  • extracellular ligand-gated ion channel activity
  • extracellular region
  • cell junction
  • integral component of membrane
  • synapse
General FunctionExtracellular ligand-gated ion channel activity
Specific FunctionBinds to acetylcholine. Modulates neuronal synaptic transmission.
Pfam Domain Function
Transmembrane RegionsNot Available
GenBank Protein IDNot Available
UniProtKB IDP58154
UniProtKB Entry NameACHP_LYMST
Cellular LocationSecreted
Gene sequenceNot Available
GenBank Gene IDNot Available
GeneCard IDNot Available
GenAtlas IDNot Available
HGNC IDNot Available
Chromosome LocationNot Available
LocusNot Available
  1. Smit AB, Syed NI, Schaap D, van Minnen J, Klumperman J, Kits KS, Lodder H, van der Schors RC, van Elk R, Sorgedrager B, Brejc K, Sixma TK, Geraerts WP: A glia-derived acetylcholine-binding protein that modulates synaptic transmission. Nature. 2001 May 17;411(6835):261-8. 11357121
  2. Brejc K, van Dijk WJ, Klaassen RV, Schuurmans M, van Der Oost J, Smit AB, Sixma TK: Crystal structure of an ACh-binding protein reveals the ligand-binding domain of nicotinic receptors. Nature. 2001 May 17;411(6835):269-76. 11357122