Probable phosphatase YcdX

NameProbable phosphatase YcdX
Synonyms
  • 3.1.3.-
Gene NameycdX
OrganismEscherichia coli (strain K12)
Amino acid sequence
>lcl|BSEQ0016853|Probable phosphatase YcdX
MYPVDLHMHTVASTHAYSTLSDYIAQAKQKGIKLFAITDHGPDMEDAPHHWHFINMRIWP
RVVDGVGILRGIEANIKNVDGEIDCSGKMFDSLDLIIAGFHEPVFAPHDKATNTQAMIAT
IASGNVHIISHPGNPKYEIDVKAVAEAAAKHQVALEINNSSFLHSRKGSEDNCREVAAAV
RDAGGWVALGSDSHTAFTMGEFEECLKILDAVDFPPERILNVSPRRLLNFLESRGMAPIA
EFADL
Number of residues245
Molecular Weight26890.25
Theoretical pI5.83
GO Classification
Functions
  • zinc ion binding
  • DNA binding
  • DNA-directed DNA polymerase activity
  • phosphoric ester hydrolase activity
  • phosphatase activity
Processes
  • DNA replication
  • bacterial-type flagellum-dependent swarming motility
Components
  • cytosol
General FunctionZinc ion binding
Specific FunctionHydrolyzes p-nitrophenyl phosphate (pNPP) in vitro. Involved in the swarming motility process.
Pfam Domain Function
Transmembrane RegionsNot Available
GenBank Protein IDNot Available
UniProtKB IDP75914
UniProtKB Entry NameYCDX_ECOLI
Cellular LocationCytoplasmic
Gene sequence
>lcl|BSEQ0016854|Probable phosphatase YcdX (ycdX)
ATGTATCCCGTCGACCTTCATATGCATACCGTTGCCAGCACACATGCATATAGCACATTA
AGTGATTACATTGCCCAGGCCAAACAAAAGGGCATTAAACTTTTTGCGATCACCGATCAT
GGCCCGGATATGGAAGATGCGCCGCATCACTGGCACTTCATTAACATGCGTATCTGGCCG
CGAGTGGTTGATGGGGTAGGGATCCTGCGCGGCATCGAAGCTAACATTAAAAATGTTGAT
GGTGAAATTGACTGCAGCGGTAAAATGTTTGACTCGCTGGATCTAATTATTGCCGGTTTT
CATGAGCCGGTTTTTGCGCCACATGACAAAGCGACCAATACACAAGCGATGATCGCCACT
ATCGCCAGCGGCAATGTGCATATAATAAGCCATCCCGGAAATCCCAAATATGAAATAGAT
GTGAAAGCCGTTGCTGAAGCAGCCGCGAAACATCAGGTGGCGCTGGAAATCAATAATTCC
TCATTTTTACACTCACGTAAGGGCAGTGAAGACAACTGTCGTGAGGTAGCCGCAGCGGTA
CGTGATGCTGGAGGTTGGGTGGCATTAGGCTCGGATTCTCACACCGCGTTTACCATGGGG
GAATTTGAAGAGTGTCTTAAAATCCTCGACGCGGTAGATTTTCCGCCAGAGCGCATTTTG
AATGTTTCTCCGCGCCGCTTACTGAACTTCCTTGAATCTCGCGGTATGGCACCGATTGCG
GAATTTGCAGACCTTTAA
GenBank Gene IDU00096
GeneCard IDNot Available
GenAtlas IDNot Available
HGNC IDNot Available
Chromosome LocationNot Available
LocusNot Available
References
  1. Oshima T, Aiba H, Baba T, Fujita K, Hayashi K, Honjo A, Ikemoto K, Inada T, Itoh T, Kajihara M, Kanai K, Kashimoto K, Kimura S, Kitagawa M, Makino K, Masuda S, Miki T, Mizobuchi K, Mori H, Motomura K, Nakamura Y, Nashimoto H, Nishio Y, Saito N, Horiuchi T, et al.: A 718-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 12.7-28.0 min region on the linkage map. DNA Res. 1996 Jun 30;3(3):137-55. 8905232
  2. Blattner FR, Plunkett G 3rd, Bloch CA, Perna NT, Burland V, Riley M, Collado-Vides J, Glasner JD, Rode CK, Mayhew GF, Gregor J, Davis NW, Kirkpatrick HA, Goeden MA, Rose DJ, Mau B, Shao Y: The complete genome sequence of Escherichia coli K-12. Science. 1997 Sep 5;277(5331):1453-62. 9278503
  3. Hayashi K, Morooka N, Yamamoto Y, Fujita K, Isono K, Choi S, Ohtsubo E, Baba T, Wanner BL, Mori H, Horiuchi T: Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110. Mol Syst Biol. 2006;2:2006.0007. Epub 2006 Feb 21. 16738553
  4. Redelberger D, Seduk F, Genest O, Mejean V, Leimkuhler S, Iobbi-Nivol C: YcdY protein of Escherichia coli, an atypical member of the TorD chaperone family. J Bacteriol. 2011 Dec;193(23):6512-6. doi: 10.1128/JB.05927-11. Epub 2011 Sep 30. 21965574
  5. Teplyakov A, Obmolova G, Khil PP, Howard AJ, Camerini-Otero RD, Gilliland GL: Crystal structure of the Escherichia coli YcdX protein reveals a trinuclear zinc active site. Proteins. 2003 May 1;51(2):315-8. 12661000