Alpha-pyrone synthesis polyketide synthase-like Pks18
| Name | Alpha-pyrone synthesis polyketide synthase-like Pks18 |
|---|---|
| Synonyms |
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| Gene Name | pks18 |
| Organism | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) |
| Amino acid sequence | >lcl|BSEQ0051264|Alpha-pyrone synthesis polyketide synthase-like Pks18 MNVSAESGAPRRAGQRHEVGLAQLPPAPPTTVAVIEGLATGTPRRVVNQSDAADRVAELF LDPGQRERIPRVYQKSRITTRRMAVDPLDAKFDVFRREPATIRDRMHLFYEHAVPLAVDV SKRALAGLPYRAAEIGLLVLATSTGFIAPGVDVAIVKELGLSPSISRVVVNFMGCAAAMN ALGTATNYVRAHPAMKALVVCIELCSVNAVFADDINDVVIHSLFGDGCAALVIGASQVQE KLEPGKVVVRSSFSQLLDNTEDGIVLGVNHNGITCELSENLPGYIFSGVAPVVTEMLWDN GLQISDIDLWAIHPGGPKIIEQSVRSLGISAELAAQSWDVLARFGNMLSVSLIFVLETMV QQAESAKAISTGVAFAFGPGVTVEGMLFDIIRR |
| Number of residues | 393 |
| Molecular Weight | 42032.07 |
| Theoretical pI | Not Available |
| GO Classification | Functions
Processes
|
| General Function | Involved in the biosynthesis of tri- and tetraketide alpha-pyrones. Pks18 catalyzes the extension of medium- and long-chain aliphatic acyl-CoA substrates by using malonyl-CoA as an extender molecule to synthesize polyketide products. |
| Specific Function | Transferase activity, transferring acyl groups other than amino-acyl groups |
| Pfam Domain Function | |
| Transmembrane Regions | Not Available |
| GenBank Protein ID | Not Available |
| UniProtKB ID | P9WPF1 |
| UniProtKB Entry Name | PKS18_MYCTU |
| Cellular Location | Not Available |
| Gene sequence | >lcl|BSEQ0051265|Alpha-pyrone synthesis polyketide synthase-like Pks18 (pks18) ATGAACGTCTCAGCTGAGAGCGGTGCGCCGCGCCGGGCCGGCCAGAGGCATGAGGTTGGC CTTGCCCAGTTGCCGCCGGCTCCGCCCACCACGGTGGCGGTGATTGAAGGGCTTGCGACG GGCACGCCGCGTCGGGTAGTCAACCAGTCCGACGCCGCCGATCGGGTCGCCGAGCTTTTC CTCGATCCCGGTCAGCGGGAACGGATTCCGCGGGTGTATCAAAAATCGCGGATCACCACG CGCCGGATGGCGGTCGACCCGCTCGACGCCAAATTTGATGTCTTCAGGCGGGAACCTGCG ACGATCCGTGATCGGATGCATCTGTTCTACGAACACGCGGTTCCGCTGGCGGTGGACGTG AGCAAGCGTGCCCTGGCCGGCCTGCCATACCGTGCCGCCGAGATCGGGCTGCTGGTGTTG GCCACCAGCACCGGATTCATCGCGCCGGGCGTGGACGTTGCGATCGTCAAAGAGCTCGGG CTCTCCCCGTCGATATCACGTGTCGTGGTCAATTTCATGGGATGTGCCGCCGCGATGAAT GCCCTGGGCACCGCCACCAACTATGTTCGTGCCCACCCGGCCATGAAGGCGCTGGTGGTG TGTATCGAATTGTGCTCGGTGAACGCTGTTTTTGCCGACGACATCAACGACGTCGTCATT CACAGCTTGTTTGGCGACGGGTGCGCGGCGTTGGTGATCGGCGCCAGCCAGGTTCAGGAG AAGCTCGAGCCAGGCAAGGTGGTAGTCCGCAGTAGTTTCAGTCAGCTGCTCGACAACACC GAAGACGGTATCGTGCTTGGCGTCAATCACAACGGCATCACCTGCGAGCTGTCGGAGAAT CTCCCCGGCTACATCTTCAGCGGGGTCGCACCGGTGGTGACAGAGATGTTATGGGACAAT GGATTACAGATATCCGATATCGATCTCTGGGCGATCCATCCGGGTGGCCCCAAGATCATC GAGCAGTCGGTGCGCTCGCTGGGGATCTCCGCGGAGCTGGCGGCGCAGAGCTGGGACGTG CTCGCCCGCTTCGGCAACATGCTCAGCGTATCGCTTATCTTTGTGCTAGAGACGATGGTG CAGCAGGCGGAGTCGGCCAAAGCCATCTCGACGGGGGTGGCGTTCGCGTTCGGGCCGGGC GTCACTGTCGAAGGCATGCTGTTCGACATCATCCGACGGTGA |
| GenBank Gene ID | Not Available |
| GeneCard ID | Not Available |
| GenAtlas ID | Not Available |
| HGNC ID | Not Available |
| Chromosome Location | Not Available |
| Locus | Not Available |
| References |
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