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Plasma membrane calcium-transporting ATPase 2
Name | Plasma membrane calcium-transporting ATPase 2 |
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Synonyms |
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Gene Name | ATP2B2 |
Organism | Human |
Amino acid sequence | >lcl|BSEQ0008771|Plasma membrane calcium-transporting ATPase 2 MGDMTNSDFYSKNQRNESSHGGEFGCTMEELRSLMELRGTEAVVKIKETYGDTEAICRRL KTSPVEGLPGTAPDLEKRKQIFGQNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIISLG LSFYHPPGEGNEGCATAQGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFR GLQSRIEQEQKFTVVRAGQVVQIPVAEIVVGDIAQVKYGDLLPADGLFIQGNDLKIDESS LTGESDQVRKSVDKDPMLLSGTHVMEGSGRMLVTAVGVNSQTGIIFTLLGAGGEEEEKKD KKGVKKGDGLQLPAADGAAASNAADSANASLVNGKMQDGNVDASQSKAKQQDGAAAMEMQ PLKSAEGGDADDRKKASMHKKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILVLYFTVDT FVVNKKPWLPECTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNL VRHLDACETMGNATAICSDKTGTLTTNRMTVVQAYVGDVHYKEIPDPSSINTKTMELLIN AIAINSAYTTKILPPEKEGALPRQVGNKTECGLLGFVLDLKQDYEPVRSQMPEEKLYKVY TFNSVRKSMSTVIKLPDESFRMYSKGASEIVLKKCCKILNGAGEPRVFRPRDRDEMVKKV IEPMACDGLRTICVAYRDFPSSPEPDWDNENDILNELTCICVVGIEDPVRPEVPEAIRKC QRAGITVRMVTGDNINTARAIAIKCGIIHPGEDFLCLEGKEFNRRIRNEKGEIEQERIDK IWPKLRVLARSSPTDKHTLVKGIIDSTHTEQRQVVAVTGDGTNDGPALKKADVGFAMGIA GTDVAKEASDIILTDDNFSSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACIT QDSPLKAVQMLWVNLIMDTFASLALATEPPTETLLLRKPYGRNKPLISRTMMKNILGHAV YQLALIFTLLFVGEKMFQIDSGRNAPLHSPPSEHYTIIFNTFVMMQLFNEINARKIHGER NVFDGIFRNPIFCTIVLGTFAIQIVIVQFGGKPFSCSPLQLDQWMWCIFIGLGELVWGQV IATIPTSRLKFLKEAGRLTQKEEIPEEELNEDVEEIDHAERELRRGQILWFRGLNRIQTQ IRVVKAFRSSLYEGLEKPESRTSIHNFMAHPEFRIEDSQPHIPLIDDTDLEEDAALKQNS SPPSSLNKNNSAIDSGINLTTDTSKSATSSSPGSPIHSLETSL |
Number of residues | 1243 |
Molecular Weight | 136875.18 |
Theoretical pI | Not Available |
GO Classification | Functions
Processes
Components
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General Function | Protein c-terminus binding |
Specific Function | This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium out of the cell. |
Pfam Domain Function | |
Transmembrane Regions | 95-115 153-173 391-410 444-461 876-895 906-926 947-969 988-1009 1029-1050 1061-1082 |
GenBank Protein ID | Not Available |
UniProtKB ID | Q01814 |
UniProtKB Entry Name | AT2B2_HUMAN |
Cellular Location | Cell junction |
Gene sequence | >lcl|BSEQ0021877|Plasma membrane calcium-transporting ATPase 2 (ATP2B2) ATGGGTGACATGACCAACAGCGACTTTTACTCCAAAAACCAAAGAAATGAGTCGAGCCAT GGGGGCGAGTTCGGGTGCACAATGGAGGAGCTCCGCTCCCTCATGGAGCTGCGGGGCACT GAGGCTGTGGTCAAGATCAAGGAGACTTATGGGGACACCGAAGCCATCTGCCGGCGCCTC AAAACCTCACCTGTTGAAGGTTTGCCGGGCACCGCTCCAGACCTGGAAAAGAGAAAGCAA ATTTTTGGGCAAAACTTTATACCTCCAAAGAAGCCAAAAACCTTCCTGCAGCTCGTGTGG GAGGCGCTGCAGGACGTGACGCTCATCATCCTGGAGATTGCCGCCATCATCTCCCTGGGG CTGTCCTTCTACCACCCGCCCGGCGAGGGCAACGAAGGATGTGCGACGGCCCAGGGTGGG GCAGAGGATGAAGGAGAGGCAGAGGCAGGTTGGATCGAGGGGGCCGCCATTCTCCTCTCA GTTATCTGTGTGGTCCTGGTCACGGCCTTCAATGACTGGAGCAAAGAGAAACAGTTCCGG GGCCTGCAGAGCCGCATCGAGCAGGAACAGAAATTTACCGTGGTCCGGGCTGGCCAGGTG GTCCAGATCCCTGTGGCTGAGATCGTGGTTGGGGACATAGCCCAGGTCAAATATGGTGAC CTCCTCCCTGCCGACGGCCTCTTCATCCAGGGCAATGACCTCAAGATTGATGAAAGCTCC CTAACTGGAGAGTCTGACCAGGTGCGCAAGTCCGTGGACAAGGACCCCATGCTGCTGTCA GGAACCCACGTGATGGAGGGCTCAGGACGGATGTTGGTGACTGCTGTGGGTGTGAACTCT CAGACTGGCATCATCTTTACCCTCCTGGGGGCTGGTGGTGAAGAGGAAGAGAAGAAAGAC AAAAAAGGTGTGAAGAAGGGGGATGGCCTTCAGCTACCAGCAGCAGACGGTGCGGCAGCT TCAAATGCTGCAGATAGTGCGAATGCCAGCCTAGTCAATGGTAAAATGCAGGATGGCAAT GTGGACGCCAGCCAGAGCAAAGCCAAACAACAGGACGGGGCAGCCGCCATGGAGATGCAG CCCCTCAAGAGTGCCGAGGGCGGCGACGCTGACGACAGGAAGAAGGCCAGCATGCACAAG AAGGAGAAGTCCGTGCTGCAGGGCAAGCTCACCAAGCTGGCTGTGCAGATCGGGAAGGCG GGCTTGGTGATGTCAGCCATCACGGTGATCATCCTGGTGCTCTACTTCACTGTGGACACC TTCGTGGTCAACAAGAAGCCGTGGCTGCCTGAGTGCACGCCCGTCTACGTGCAGTACTTT GTCAAGTTCTTCATCATTGGCGTGACGGTGCTGGTGGTCGCCGTGCCCGAGGGGCTCCCT CTGGCCGTCACCATCTCGTTGGCCTATTCGGTGAAGAAAATGATGAAGGACAACAACCTG GTACGCCACCTGGATGCCTGTGAGACCATGGGCAATGCCACAGCCATCTGCTCAGACAAG ACAGGCACGCTGACCACCAATCGCATGACAGTGGTACAGGCCTATGTCGGCGACGTCCAC TATAAAGAGATCCCCGACCCCAGCTCCATCAACACCAAGACCATGGAGCTGCTGATCAAT GCCATCGCCATCAACAGCGCCTACACCACCAAGATTCTGCCCCCAGAGAAGGAGGGCGCC CTGCCTCGGCAGGTGGGCAACAAGACGGAGTGCGGCCTGCTGGGCTTCGTGCTGGACCTG AAGCAGGACTACGAGCCCGTGCGCAGCCAGATGCCAGAGGAGAAGTTGTACAAAGTGTAC ACCTTCAACTCCGTGCGCAAGTCCATGAGCACTGTCATCAAGCTGCCCGACGAGAGCTTC CGCATGTACAGCAAGGGGGCTTCTGAGATCGTGCTCAAGAAGTGCTGCAAAATCCTCAAT GGGGCGGGAGAGCCTCGTGTCTTCCGGCCCCGCGACCGGGACGAGATGGTAAAGAAGGTG ATTGAGCCCATGGCTTGCGATGGGCTCCGCACTATCTGCGTGGCCTACCGCGACTTCCCC AGCAGCCCGGAGCCGGACTGGGACAATGAGAATGACATCCTCAACGAACTCACCTGCATC TGCGTGGTGGGCATCGAGGACCCGGTGCGGCCAGAGGTCCCAGAAGCCATCCGCAAGTGC CAGCGGGCAGGCATCACGGTCCGCATGGTCACTGGCGACAATATCAACACGGCTCGGGCC ATCGCCATCAAGTGTGGCATCATCCATCCTGGGGAGGACTTTCTGTGCCTCGAGGGCAAG GAGTTCAACAGGAGGATCCGCAACGAGAAGGGGGAGATTGAGCAGGAGCGAATTGACAAG ATCTGGCCAAAGCTGCGGGTGCTGGCTCGCTCCTCCCCAACGGACAAGCATACCCTGGTT AAAGGCATCATCGACAGCACACACACTGAGCAGCGGCAGGTGGTGGCCGTGACGGGGGAC GGGACCAACGACGGGCCTGCACTCAAGAAGGCCGACGTGGGCTTCGCCATGGGCATCGCA GGCACTGACGTGGCCAAGGAGGCCTCAGACATCATCCTGACAGACGACAATTTCAGCAGC ATCGTCAAGGCAGTGATGTGGGGCCGCAACGTCTATGACAGCATCTCCAAATTCTTGCAG TTCCAGCTCACCGTCAACGTGGTGGCCGTGATTGTGGCCTTCACAGGCGCCTGCATCACG CAGGACTCCCCTCTGAAGGCCGTGCAGATGCTCTGGGTGAACCTCATCATGGACACGTTT GCCTCGCTGGCACTGGCCACTGAGCCGCCCACGGAGACCCTGCTGCTGAGGAAGCCGTAC GGCCGCAACAAGCCGCTCATCTCCAGGACCATGATGAAGAACATCCTGGGCCATGCTGTC TACCAGCTTGCCCTCATCTTCACCCTGCTCTTTGTTGGCGAGAAGATGTTCCAGATCGAC AGCGGGAGGAACGCGCCCCTGCATTCGCCACCCTCAGAACATTACACCATCATCTTCAAC ACCTTCGTCATGATGCAGCTCTTCAACGAGATCAACGCCCGCAAGATCCACGGCGAGCGC AATGTCTTTGACGGCATCTTCCGGAACCCCATCTTCTGCACCATCGTGCTGGGCACCTTT GCCATCCAGATAGTGATCGTGCAGTTTGGAGGGAAGCCATTCAGCTGCTCTCCACTGCAG CTGGACCAGTGGATGTGGTGCATATTCATTGGGTTAGGAGAGCTCGTTTGGGGCCAGGTC ATCGCCACCATCCCGACCAGCAGACTCAAGTTCCTCAAGGAGGCAGGCAGGCTCACACAG AAGGAGGAGATCCCGGAGGAGGAGCTCAACGAGGACGTGGAGGAGATCGACCACGCGGAG CGGGAGCTGCGGCGGGGCCAGATCCTGTGGTTCCGAGGCCTGAATCGGATCCAGACACAG ATCCGCGTCGTGAAGGCGTTCCGTAGCTCTCTCTATGAAGGTTTAGAAAAGCCTGAATCT CGAACCTCCATCCATAACTTCATGGCTCATCCTGAATTCCGGATCGAAGATTCCCAGCCC CACATCCCCCTCATTGATGACACCGACCTGGAAGAAGATGCCGCGCTCAAGCAGAACTCG AGCCCGCCGTCATCCCTCAACAAGAACAACAGCGCCATCGACAGTGGGATCAACCTGACG ACCGACACAAGCAAATCAGCTACCTCTTCAAGTCCAGGGAGCCCCATCCACAGCCTGGAG ACGTCGCTTTAG |
GenBank Gene ID | Not Available |
GeneCard ID | Not Available |
GenAtlas ID | Not Available |
HGNC ID | HGNC:815 |
Chromosome Location | 3 |
Locus | Not Available |
References |
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