NameKinesin-like protein KIF22
Synonyms
  • KID
  • Kinesin-like DNA-binding protein
  • Kinesin-like protein 4
  • KNSL4
Gene NameKIF22
OrganismHuman
Amino acid sequence
>lcl|BSEQ0009153|Kinesin-like protein KIF22
MAAGGSTQQRRREMAAASAAAISGAGRCRLSKIGATRRPPPARVRVAVRLRPFVDGTAGA
SDPPCVRGMDSCSLEIANWRNHQETLKYQFDAFYGERSTQQDIYAGSVQPILRHLLEGQN
ASVLAYGPTGAGKTHTMLGSPEQPGVIPRALMDLLQLTREEGAEGRPWALSVTMSYLEIY
QEKVLDLLDPASGDLVIREDCRGNILIPGLSQKPISSFADFERHFLPASRNRTVGATRLN
QRSSRSHAVLLVKVDQRERLAPFRQREGKLYLIDLAGSEDNRRTGNKGLRLKESGAINTS
LFVLGKVVDALNQGLPRVPYRDSKLTRLLQDSLGGSAHSILIANIAPERRFYLDTVSALN
FAARSKEVINRPFTNESLQPHALGPVKLSQKELLGPPEAKRARGPEEEEIGSPEPMAAPA
SASQKLSPLQKLSSMDPAMLERLLSLDRLLASQGSQGAPLLSTPKRERMVLMKTVEEKDL
EIERLKTKQKELEAKMLAQKAEEKENHCPTMLRPLSHRTVTGAKPLKKAVVMPLQLIQEQ
AASPNAEIHILKNKGRKRKLESLDALEPEEKAEDCWELQISPELLAHGRQKILDLLNEGS
ARDLRSLQRIGPKKAQLIVGWRELHGPFSQVEDLERVEGITGKQMESFLKANILGLAAGQ
RCGAS
Number of residues665
Molecular Weight73261.38
Theoretical pINot Available
GO Classification
Functions
  • DNA binding
  • ATPase activity
  • microtubule motor activity
  • ATP binding
Processes
  • metaphase plate congression
  • blood coagulation
  • sister chromatid cohesion
  • DNA repair
  • mitotic nuclear division
  • antigen processing and presentation of exogenous peptide antigen via MHC class II
  • microtubule-based movement
  • mitotic metaphase plate congression
Components
  • microtubule
  • nucleus
  • chromatin
  • cytosol
  • focal adhesion
  • mitotic spindle
  • cytoplasm
  • kinesin complex
  • kinetochore
General FunctionMicrotubule motor activity
Specific FunctionKinesin family that is involved in spindle formation and the movements of chromosomes during mitosis and meiosis. Binds to microtubules and to DNA.
Pfam Domain Function
Transmembrane RegionsNot Available
GenBank Protein IDNot Available
UniProtKB IDQ14807
UniProtKB Entry NameKIF22_HUMAN
Cellular LocationNucleus
Gene sequence
>lcl|BSEQ0013643|Kinesin-like protein KIF22 (KIF22)
ATGGACAGCTGCTCTCTAGAGATTGCTAACTGGAGGAACCACCAGGAGACTCTCAAATAC
CAGTTTGATGCCTTCTATGGGGAGAGGAGTACTCAGCAGGACATCTATGCAGGTTCAGTG
CAGCCCATCCTAAGGCACTTGCTGGAAGGGCAGAATGCCAGTGTGCTTGCCTATGGACCC
ACAGGAGCTGGGAAGACGCACACAATGCTGGGCAGCCCAGAGCAACCTGGGGTGATCCCG
CGGGCTCTCATGGACCTCCTGCAGCTCACAAGGGAGGAGGGTGCCGAGGGCCGGCCATGG
GCCCTTTCTGTCACCATGTCTTACCTAGAGATCTACCAGGAGAAGGTATTAGACCTCCTG
GACCCTGCTTCGGGAGACCTGGTAATCCGAGAAGACTGCCGGGGGAATATCCTGATTCCG
GGTCTCTCCCAGAAGCCCATCAGTAGCTTTGCTGATTTTGAGCGGCACTTCCTGCCAGCC
AGTCGAAATCGGACTGTAGGAGCCACCCGGCTCAACCAGCGCTCCTCCCGCAGTCATGCT
GTGCTCCTGGTCAAGGTGGACCAGCGGGAACGTTTGGCCCCATTTCGCCAGCGAGAGGGA
AAACTCTACCTGATTGACTTGGCTGGGTCAGAGGACAACCGGCGCACAGGCAACAAGGGC
CTTCGGCTAAAAGAGAGTGGAGCCATCAACACCTCCCTGTTTGTCCTGGGCAAAGTGGTA
GATGCGCTGAATCAGGGCCTCCCTCGTGTACCTTATCGGGACAGCAAGCTCACTCGCCTA
TTGCAGGACTCTCTGGGTGGCTCAGCCCACAGTATCCTTATTGCCAACATTGCCCCTGAG
AGACGCTTCTACCTAGACACAGTCTCCGCACTCAACTTTGCTGCCAGGTCCAAGGAGGTG
ATCAATCGGCCTTTTACCAATGAGAGCCTGCAGCCTCATGCCTTGGGACCTGTTAAGCTG
TCTCAGAAAGAATTGCTTGGTCCACCAGAGGCAAAGAGAGCCCGAGGCCCTGAGGAAGAG
GAGATCGGGAGCCCTGAGCCCATGGCAGCTCCAGCCTCTGCCTCCCAGAAACTCAGCCCC
CTACAGAAGCTAAGCAGCATGGACCCGGCCATGCTGGAGCGCCTCCTCAGCTTGGACCGT
CTGCTTGCCTCCCAGGGGAGCCAGGGGGCCCCTCTGTTGAGTACCCCAAAGCGAGAGCGG
ATGGTGCTAATGAAGACAGTGGAAGAGAAGGACCTAGAGATTGAGAGGCTTAAGACGAAG
CAAAAAGAACTGGAGGCCAAGATGTTGGCCCAGAAGGCTGAGGAAAAGGAGAACCATTGT
CCCACAATGCTCCGGCCCCTTTCACATCGCACAGTCACAGGGGCAAAGCCCCTGAAAAAG
GCTGTGGTGATGCCCCTACAGCTAATTCAGGAGCAGGCAGCATCCCCAAATGCCGAGATC
CACATCCTGAAGAATAAAGGCCGGAAGAGAAAGCTGGAGTCCCTGGATGCCCTAGAGCCT
GAGGAGAAGGCTGAGGACTGCTGGGAGCTACAGATCAGCCCGGAGCTACTGGCTCATGGG
CGCCAAAAAATACTGGATCTGCTGAACGAAGGCTCAGCCCGAGATCTCCGCAGTCTTCAG
CGCATTGGCCCGAAGAAGGCCCAGCTAATCGTGGGCTGGCGGGAGCTCCACGGCCCCTTC
AGCCAGGTGGAGGACCTGGAACGCGTGGAGGGCATAACGGGGAAACAGATGGAGTCCTTC
CTGAAGGCAAACATCCTGGGTCTCGCCGCCGGCCAGCGCTGTGGCGCCTCCTGA
GenBank Gene IDNot Available
GeneCard IDNot Available
GenAtlas IDNot Available
HGNC IDHGNC:6391
Chromosome Location16
LocusNot Available
References
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