NameKinesin-like protein KIF24
Synonyms
  • C9orf48
Gene NameKIF24
OrganismHuman
Amino acid sequence
>lcl|BSEQ0009155|Kinesin-like protein KIF24
MASWLYECLCEAELAQYYSHFTALGLQKIDELAKITMKDYSKLGVHDMNDRKRLFQLIKI
IKIMQEEDKAVSIPERHLQTSSLRIKSQELRSGPRRQLNFDSPADNKDRNASNDGFEMCS
LSDFSANEQKSTYLKVLEHMLPDDSQYHTKTGILNATAGDSYVQTEISTSLFSPNYLSAI
LGDCDIPIIQRISHVSGYNYGIPHSCIRQNTSEKQNPWTEMEKIRVCVRKRPLGMREVRR
GEINIITVEDKETLLVHEKKEAVDLTQYILQHVFYFDEVFGEACTNQDVYMKTTHPLIQH
IFNGGNATCFAYGQTGAGKTYTMIGTHENPGLYALAAKDIFRQLEVSQPRKHLFVWISFY
EIYCGQLYDLLNRRKRLFAREDSKHMVQIVGLQELQVDSVELLLEVILKGSKERSTGATG
VNADSSRSHAVIQIQIKDSAKRTFGRISFIDLAGSERAADARDSDRQTKMEGAEINQSLL
ALKECIRALDQEHTHTPFRQSKLTQVLKDSFIGNAKTCMIANISPSHVATEHTLNTLRYA
DRVKELKKGIKCCTSVTSRNRTSGNSSPKRIQSSPGALSEDKCSPKKVKLGFQQSLTVAA
PGSTRGKVHPLTSHPPNIPFTSAPKVSGKRGGSRGSPSQEWVIHASPVKGTVRSGHVAKK
KPEESAPLCSEKNRMGNKTVLGWESRASGPGEGLVRGKLSTKCKKVQTVQPVQKQLVSRV
ELSFGNAHHRAEYSQDSQRGTPARPASEAWTNIPPHQKEREEHLRFYHQQFQQPPLLQQK
LKYQPLKRSLRQYRPPEGQLTNETPPLFHSYSENHDGAQVEELDDSDFSEDSFSHISSQR
ATKQRNTLENSEDSFFLHQTWGQGPEKQVAERQQSLFSSPRTGDKKDLTKSWVDSRDPIN
HRRAALDHSCSPSKGPVDWSRENSTSSGPSPRDSLAEKPYCSQVDFIYRQERGGGSSFDL
RKDASQSEVSGENEGNLPSPEEDGFTISLSHVAVPGSPDQRDTVTTPLREVSADGPIQVT
STVKNGHAVPGEDPRGQLGTHAEYASGLMSPLTMSLLENPDNEGSPPSEQLVQDGATHSL
VAESTGGPVVSHTVPSGDQEAALPVSSATRHLWLSSSPPDNKPGGDLPALSPSPIRQHPA
DKLPSREADLGEACQSRETVLFSHEHMGSEQYDADAEETGLDGSWGFPGKPFTTIHMGVP
HSGPTLTPRTGSSDVADQLWAQERKHPTRLGWQEFGLSTDPIKLPCNSENVTWLKPRPIS
RCLARPSSPLVPSCSPKTAGTLRQPTLEQAQQVVIRAHQEQLDEMAELGFKEETLMSQLA
SNDFEDFVTQLDEIMVLKSKCIQSLRSQLQLYLTCHGPTAAPEGTVPS
Number of residues1368
Molecular Weight151902.055
Theoretical pINot Available
GO Classification
Functions
  • ATP binding
  • ATPase activity
  • microtubule motor activity
Processes
  • microtubule depolymerization
  • microtubule-based movement
  • organelle organization
  • cilium assembly
Components
  • centriole
  • protein complex
  • microtubule
  • cytosol
  • kinesin complex
General FunctionMicrotubule motor activity
Specific FunctionMicrotubule-dependent motor protein that acts as a negative regulator of ciliogenesis by mediating recruitment of CCP110 to mother centriole in cycling cells, leading to restrict nucleation of cilia at centrioles. Mediates depolymerization of microtubules of centriolar origin, possibly to suppress aberrant cilia formation.
Pfam Domain Function
Transmembrane RegionsNot Available
GenBank Protein IDNot Available
UniProtKB IDQ5T7B8
UniProtKB Entry NameKIF24_HUMAN
Cellular LocationCytoplasm
Gene sequence
>lcl|BSEQ0013644|Kinesin-like protein KIF24 (KIF24)
ATGGCATCCTGGTTATATGAATGTCTTTGTGAAGCTGAACTTGCACAGTATTATTCTCAT
TTCACTGCCCTTGGCCTTCAGAAAATAGATGAATTAGCCAAGATTACAATGAAGGACTAC
TCCAAATTAGGAGTCCATGACATGAACGACCGCAAACGTCTCTTCCAACTTATCAAAATT
ATTAAGATTATGCAAGAAGAAGATAAAGCAGTCAGTATCCCAGAGCGTCATCTTCAGACA
AGCAGCCTGCGCATCAAATCTCAGGAATTAAGATCTGGCCCTCGCAGACAGCTGAATTTT
GATTCTCCTGCTGACAATAAAGACAGAAATGCCAGCAATGATGGGTTTGAAATGTGCAGT
TTATCAGATTTCTCTGCAAATGAACAGAAGTCCACTTACCTAAAAGTGCTAGAACACATG
CTACCAGATGATTCCCAGTACCATACAAAAACAGGAATTCTGAATGCCACAGCTGGTGAT
TCCTATGTGCAAACAGAAATCAGCACTTCACTCTTTTCACCAAATTACCTTTCTGCAATA
CTGGGGGATTGTGATATTCCCATTATTCAAAGAATCTCTCATGTTTCAGGGTATAACTAT
GGAATCCCTCATTCTTGTATCAGACAGAACACTTCAGAGAAACAGAATCCTTGGACTGAG
ATGGAGAAAATCAGAGTTTGTGTTCGAAAACGCCCCCTGGGCATGAGGGAGGTACGTCGT
GGAGAAATTAATATTATTACTGTAGAAGACAAAGAAACTCTACTTGTGCATGAGAAGAAA
GAAGCAGTTGACCTCACTCAATATATTCTGCAGCATGTTTTTTATTTTGATGAAGTCTTT
GGTGAGGCGTGCACCAATCAGGATGTATACATGAAGACTACTCACCCACTTATTCAGCAT
ATTTTCAATGGAGGCAATGCCACTTGCTTTGCTTATGGACAGACAGGTGCTGGAAAGACC
TACACCATGATAGGAACTCATGAGAACCCAGGATTGTATGCTCTAGCTGCCAAAGATATC
TTCAGGCAACTAGAAGTGTCCCAGCCAAGAAAGCACCTCTTTGTGTGGATCAGCTTCTAT
GAAATTTACTGTGGACAGCTTTATGACCTCCTAAATAGAAGAAAAAGGCTCTTTGCAAGA
GAAGATAGCAAGCACATGGTGCAGATAGTGGGACTGCAAGAGCTTCAGGTGGACAGTGTG
GAGCTCCTCTTAGAGGTGATCTTAAAGGGCAGCAAGGAGCGCAGCACTGGGGCCACTGGA
GTTAATGCAGACTCCTCCCGCTCCCATGCCGTCATCCAAATTCAGATCAAAGATTCAGCC
AAGAGGACATTTGGCAGGATCTCTTTTATTGACTTGGCTGGCAGTGAAAGAGCAGCAGAT
GCAAGGGACTCAGATAGACAGACAAAGATGGAAGGTGCAGAAATAAATCAGAGTCTACTG
GCTCTGAAGGAATGTATCCGAGCACTGGATCAGGAACACACCCATACTCCCTTCAGGCAA
AGCAAACTAACTCAGGTCCTGAAGGACTCTTTCATCGGCAATGCCAAAACCTGCATGATC
GCCAACATCTCACCAAGCCACGTGGCCACTGAACACACTCTCAACACCTTGCGCTATGCT
GACCGGGTCAAAGAACTAAAGAAAGGCATTAAGTGTTGCACTTCAGTTACCAGTCGAAAT
CGGACATCTGGAAACTCCTCTCCAAAACGAATTCAGAGCTCCCCTGGGGCTTTGTCAGAG
GACAAATGTTCTCCCAAAAAAGTCAAGCTGGGATTTCAGCAGTCACTCACAGTGGCAGCC
CCTGGTTCCACGAGAGGGAAGGTCCATCCTCTGACCAGCCACCCACCCAACATTCCTTTT
ACTTCTGCACCTAAGGTCTCTGGTAAAAGGGGTGGCTCCAGAGGGAGTCCTTCACAAGAG
TGGGTCATTCATGCTAGCCCTGTGAAAGGAACTGTGCGCTCTGGACATGTGGCCAAAAAA
AAGCCAGAAGAGTCAGCACCATTGTGCTCTGAGAAAAATCGAATGGGCAACAAAACTGTC
CTTGGGTGGGAAAGCAGGGCCTCAGGCCCAGGAGAAGGCCTAGTGCGTGGTAAGCTGTCC
ACCAAGTGCAAGAAAGTGCAGACAGTGCAGCCAGTACAGAAGCAGCTTGTGTCTCGAGTT
GAGCTCTCCTTTGGCAACGCCCACCACAGGGCTGAGTACAGTCAAGACAGCCAGAGGGGC
ACGCCTGCTAGGCCTGCCTCTGAAGCTTGGACAAACATCCCGCCACATCAGAAGGAGAGG
GAGGAACATCTGCGTTTCTATCACCAGCAGTTCCAACAGCCACCTCTCCTCCAACAGAAG
TTAAAATACCAACCACTGAAAAGGTCTTTACGCCAGTACAGGCCCCCAGAGGGTCAGCTC
ACGAATGAGACTCCGCCTCTGTTCCACTCTTACTCTGAAAACCATGATGGAGCCCAAGTA
GAGGAACTTGATGACAGTGATTTCAGTGAAGATTCTTTTTCACACATCTCTAGTCAGAGG
GCCACAAAGCAAAGGAACACCCTGGAGAATAGCGAAGACTCATTCTTCCTGCACCAGACG
TGGGGACAGGGTCCTGAGAAGCAGGTGGCAGAAAGACAGCAGAGTCTGTTTTCTAGCCCC
AGGACAGGTGACAAGAAAGATCTAACTAAAAGCTGGGTGGACTCCAGGGACCCCATAAAC
CACAGAAGAGCAGCACTCGATCACAGCTGCAGCCCAAGTAAGGGGCCCGTGGACTGGAGC
AGAGAGAACTCTACTTCCTCAGGGCCTTCTCCCAGAGACAGCCTGGCAGAGAAGCCATAC
TGTTCACAGGTAGATTTCATATATAGACAGGAAAGAGGTGGAGGCTCTTCCTTTGATCTC
AGAAAGGATGCCTCCCAAAGTGAGGTTTCTGGGGAGAATGAGGGCAACTTGCCATCCCCA
GAGGAAGATGGTTTCACTATCTCATTGTCCCACGTTGCAGTTCCTGGATCCCCAGACCAA
AGAGACACAGTCACCACACCTCTGAGAGAAGTCAGTGCAGACGGCCCAATCCAGGTGACC
AGCACTGTGAAAAACGGTCATGCTGTCCCAGGAGAGGATCCTAGGGGGCAGTTAGGCACG
CATGCTGAATATGCTTCTGGACTCATGTCTCCCCTCACCATGTCCCTCCTGGAGAACCCA
GACAACGAAGGGTCTCCTCCCTCGGAGCAGCTGGTCCAGGATGGGGCTACGCACAGTCTA
GTGGCAGAGAGCACAGGGGGCCCAGTTGTGAGCCACACAGTGCCATCTGGTGATCAAGAG
GCAGCCTTGCCAGTGTCTTCAGCAACTAGGCACCTGTGGCTGTCCTCATCTCCCCCTGAT
AATAAGCCTGGTGGTGATCTTCCAGCTCTGTCCCCATCACCCATCCGTCAGCACCCAGCT
GACAAGCTGCCCAGCAGGGAGGCAGACCTAGGAGAGGCCTGCCAGAGCAGAGAGACTGTA
CTTTTCTCCCACGAACACATGGGTAGTGAGCAGTATGATGCTGATGCAGAGGAGACGGGG
CTGGATGGCTCCTGGGGTTTCCCAGGAAAGCCCTTCACCACCATACATATGGGGGTACCC
CATTCTGGACCTACACTCACCCCACGAACAGGAAGTAGTGATGTGGCTGACCAGCTCTGG
GCCCAGGAGAGAAAACATCCTACAAGGCTTGGTTGGCAGGAGTTTGGTTTGTCCACAGAC
CCCATCAAGTTGCCCTGCAACAGTGAAAATGTCACATGGCTCAAACCCAGGCCGATCTCA
AGGTGCTTAGCAAGGCCAAGTTCTCCCTTGGTTCCCAGCTGCTCTCCCAAGACTGCAGGG
ACACTCCGTCAGCCCACCCTGGAGCAAGCGCAGCAGGTGGTCATCCGAGCACACCAGGAA
CAGCTGGATGAAATGGCTGAGCTCGGCTTCAAGGAGGAGACGCTGATGAGCCAGCTGGCT
TCTAATGATTTTGAAGATTTTGTGACCCAGCTGGATGAAATCATGGTTCTGAAATCCAAG
TGTATCCAGAGTCTGAGGAGCCAGCTGCAGCTCTATCTCACCTGCCACGGGCCCACCGCA
GCCCCTGAGGGAACAGTGCCGTCTTAG
GenBank Gene IDNot Available
GeneCard IDNot Available
GenAtlas IDNot Available
HGNC IDHGNC:19916
Chromosome Location9
LocusNot Available
References
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