T3DB: Solute carrier family 2, facilitated glucose transporter member 7

Name	Solute carrier family 2, facilitated glucose transporter member 7
Synonyms	Glucose transporter type 7 GLUT-7 GLUT7
Gene Name	SLC2A7
Organism	Human
Amino acid sequence	>lcl\|BSEQ0019707\|Solute carrier family 2, facilitated glucose transporter member 7 MENKEAGTPPPIPSREGRLQPTLLLATLSAAFGSAFQYGYNLSVVNTPHKVFKSFYNETY FERHATFMDGKLMLLLWSCTVSMFPLGGLLGSLLVGLLVDSCGRKGTLLINNIFAIIPAI LMGVSKVAKAFELIVFSRVVLGVCAGISYSALPMYLGELAPKNLRGMVGTMTEVFVIVGV FLAQIFSLQAILGNPAGWPVLLALTGVPALLQLLTLPFFPESPRYSLIQKGDEATARQAL RRLRGHTDMEAELEDMRAEARAERAEGHLSVLHLCALRSLRWQLLSIIVLMAGQQLSGIN AINYYADTIYTSAGVEAAHSQYVTVGSGVVNIVMTITSAVLVERLGRRHLLLAGYGICGS ACLVLTVVLLFQNRVPELSYLGIICVFAYIAGHSIGPSPVPSVVRTEIFLQSSRRAAFMV DGAVHWLTNFIIGFLFPSIQEAIGAYSFIIFAGICLLTAIYIYVVIPETKGKTFVEINRI FAKRNRVKLPEEKEETIDAGPPTASPAKETSF
Number of residues	512
Molecular Weight	55726.915
Theoretical pI	Not Available
GO Classification	Functions substrate-specific transmembrane transporter activity Processes carbohydrate transport transmembrane transport Components plasma membrane integral component of membrane
General Function	Substrate-specific transmembrane transporter activity
Specific Function	High-affinity transporter for glucose and fructose Does not transport galactose, 2-deoxy-d-glucose and xylose.
Pfam Domain Function	Sugar_tr (PF00083 )
Transmembrane Regions	22-42 79-99 108-128 139-159 173-193 199-219 282-302 322-342 351-371 380-400 416-436 446-466
GenBank Protein ID	Not Available
UniProtKB ID	Q6PXP3
UniProtKB Entry Name	GTR7_HUMAN
Cellular Location	Membrane
Gene sequence	>lcl\|BSEQ0019708\|Solute carrier family 2, facilitated glucose transporter member 7 (SLC2A7) ATGGAGAACAAAGAGGCGGGAACCCCTCCACCCATTCCATCCAGGGAGGGGCGGCTCCAG CCGACGCTGTTGCTGGCGACACTGAGCGCGGCCTTTGGCTCAGCCTTCCAGTACGGCTAC AACCTCTCTGTGGTCAACACGCCGCACAAGGTCTTCAAGTCATTTTACAACGAAACCTAC TTTGAGCGACACGCAACATTCATGGACGGGAAGCTCATGCTGCTTCTATGGTCTTGCACC GTCTCCATGTTTCCTCTGGGCGGCCTGTTGGGGTCATTGCTCGTGGGCCTGCTGGTTGAT AGCTGCGGCAGAAAGGGGACCCTGCTGATCAACAACATCTTTGCCATCATCCCCGCCATC CTGATGGGAGTCAGCAAAGTGGCCAAGGCTTTTGAGCTGATCGTCTTTTCCCGAGTGGTG CTGGGAGTCTGTGCAGGCATCTCCTACAGCGCCCTTCCCATGTACCTGGGAGAACTGGCC CCCAAGAACCTGAGAGGCATGGTGGGAACAATGACCGAGGTTTTCGTCATCGTTGGAGTC TTCCTAGCACAGATCTTCAGCCTCCAGGCCATCTTGGGCAACCCGGCAGGCTGGCCGGTG CTTCTGGCGCTCACAGGGGTGCCCGCCCTGCTGCAGCTGCTGACCCTGCCCTTCTTCCCC GAAAGCCCCCGCTACTCCCTGATTCAGAAAGGAGATGAAGCCACAGCGCGACAAGCTCTG AGGAGGCTGAGAGGCCACACGGACATGGAGGCCGAGCTGGAGGACATGCGTGCGGAGGCC CGGGCCGAGCGCGCCGAGGGCCACCTGTCTGTGCTGCACCTCTGTGCCCTGCGGTCCCTG CGCTGGCAGCTCCTCTCCATCATCGTGCTCATGGCCGGCCAGCAGCTGTCGGGCATCAAT GCGATCAACTACTATGCGGACACCATCTACACATCTGCGGGCGTGGAGGCCGCTCACTCC CAATATGTAACGGTGGGCTCTGGCGTCGTCAACATAGTGATGACCATCACCTCGGCTGTC CTTGTGGAGCGGCTGGGACGGCGGCACCTCCTGCTGGCCGGCTACGGCATCTGCGGCTCT GCCTGCCTGGTGCTGACGGTGGTGCTCCTATTCCAGAACAGGGTCCCCGAGCTGTCCTAC CTCGGCATCATCTGTGTCTTTGCCTACATCGCGGGACATTCCATTGGGCCCAGTCCTGTC CCCTCGGTGGTGAGGACCGAGATCTTCCTGCAGTCCTCCCGGCGGGCAGCTTTCATGGTG GACGGGGCAGTGCACTGGCTCACCAACTTCATCATAGGCTTCCTGTTCCCATCCATCCAG GAGGCCATCGGTGCCTACAGTTTCATCATCTTTGCCGGAATCTGCCTCCTCACTGCGATT TACATCTACGTGGTTATTCCGGAGACCAAGGGCAAAACATTTGTGGAGATAAACCGCATT TTTGCCAAGAGAAACAGGGTGAAGCTTCCAGAGGAGAAAGAAGAAACCATTGATGCTGGG CCTCCCACAGCCTCTCCTGCCAAGGAAACTTCCTTTTAG
GenBank Gene ID	Not Available
GeneCard ID	Not Available
GenAtlas ID	Not Available
HGNC ID	HGNC:13445
Chromosome Location	1
Locus	Not Available
References	Li Q, Manolescu A, Ritzel M, Yao S, Slugoski M, Young JD, Chen XZ, Cheeseman CI: Cloning and functional characterization of the human GLUT7 isoform SLC2A7 from the small intestine. Am J Physiol Gastrointest Liver Physiol. 2004 Jul;287(1):G236-42. Epub 2004 Mar 19. 15033637 Gregory SG, Barlow KF, McLay KE, Kaul R, Swarbreck D, Dunham A, Scott CE, Howe KL, Woodfine K, Spencer CC, Jones MC, Gillson C, Searle S, Zhou Y, Kokocinski F, McDonald L, Evans R, Phillips K, Atkinson A, Cooper R, Jones C, Hall RE, Andrews TD, Lloyd C, Ainscough R, Almeida JP, Ambrose KD, Anderson F, Andrew RW, Ashwell RI, Aubin K, Babbage AK, Bagguley CL, Bailey J, Beasley H, Bethel G, Bird CP, Bray-Allen S, Brown JY, Brown AJ, Buckley D, Burton J, Bye J, Carder C, Chapman JC, Clark SY, Clarke G, Clee C, Cobley V, Collier RE, Corby N, Coville GJ, Davies J, Deadman R, Dunn M, Earthrowl M, Ellington AG, Errington H, Frankish A, Frankland J, French L, Garner P, Garnett J, Gay L, Ghori MR, Gibson R, Gilby LM, Gillett W, Glithero RJ, Grafham DV, Griffiths C, Griffiths-Jones S, Grocock R, Hammond S, Harrison ES, Hart E, Haugen E, Heath PD, Holmes S, Holt K, Howden PJ, Hunt AR, Hunt SE, Hunter G, Isherwood J, James R, Johnson C, Johnson D, Joy A, Kay M, Kershaw JK, Kibukawa M, Kimberley AM, King A, Knights AJ, Lad H, Laird G, Lawlor S, Leongamornlert DA, Lloyd DM, Loveland J, Lovell J, Lush MJ, Lyne R, Martin S, Mashreghi-Mohammadi M, Matthews L, Matthews NS, McLaren S, Milne S, Mistry S, Moore MJ, Nickerson T, O'Dell CN, Oliver K, Palmeiri A, Palmer SA, Parker A, Patel D, Pearce AV, Peck AI, Pelan S, Phelps K, Phillimore BJ, Plumb R, Rajan J, Raymond C, Rouse G, Saenphimmachak C, Sehra HK, Sheridan E, Shownkeen R, Sims S, Skuce CD, Smith M, Steward C, Subramanian S, Sycamore N, Tracey A, Tromans A, Van Helmond Z, Wall M, Wallis JM, White S, Whitehead SL, Wilkinson JE, Willey DL, Williams H, Wilming L, Wray PW, Wu Z, Coulson A, Vaudin M, Sulston JE, Durbin R, Hubbard T, Wooster R, Dunham I, Carter NP, McVean G, Ross MT, Harrow J, Olson MV, Beck S, Rogers J, Bentley DR, Banerjee R, Bryant SP, Burford DC, Burrill WD, Clegg SM, Dhami P, Dovey O, Faulkner LM, Gribble SM, Langford CF, Pandian RD, Porter KM, Prigmore E: The DNA sequence and biological annotation of human chromosome 1. Nature. 2006 May 18;441(7091):315-21. 16710414