NameAquaporin-12A
Synonyms
  • AQP-12
  • AQP12
  • AQPX2
Gene NameAQP12A
OrganismHuman
Amino acid sequence
>lcl|BSEQ0013390|Aquaporin-12A
MAGLNVSLSFFFATFALCEAARRASKALLPVGAYEVFAREAMRTLVELGPWAGDFGPDLL
LTLLFLLFLAHGVTLDGASANPTVSLQEFLMAEQSLPGTLLKLAAQGLGMQAACTLMRLC
WAWELSDLHLLQSLMAQSCSSALRTSVPHGALVEAACAFCFHLTLLHLRHSPPAYSGPAV
ALLVTVTAYTAGPFTSAFFNPALAASVTFACSGHTLLEYVQVYWLGPLTGMVLAVLLHQG
RLPHLFQRNLFYGQKNKYRAPRGKPAPASGDTQTPAKGSSVREPGRSGVEGPHSS
Number of residues295
Molecular Weight31474.21
Theoretical pINot Available
GO Classification
Functions
  • transporter activity
Components
  • integral component of membrane
General FunctionTransporter activity
Specific FunctionAquaporins facilitate the transport of water and small neutral solutes across cell membranes.
Pfam Domain Function
Transmembrane Regions1-21 55-75 100-126 146-166 179-199 216-236
GenBank Protein IDNot Available
UniProtKB IDQ8IXF9
UniProtKB Entry NameAQ12A_HUMAN
Cellular LocationMembrane
Gene sequence
>lcl|BSEQ0013391|Aquaporin-12A (AQP12A)
ATGGCAGGTCTTAACGTGTCCCTCTCCTTCTTCTTTGCCACCTTCGCCCTCTGTGAGGCG
GCCAGGCGGGCCTCCAAGGCCCTGCTCCCAGTGGGCGCCTATGAAGTCTTCGCCCGGGAG
GCGATGAGGACGCTGGTCGAGCTCGGGCCCTGGGCTGGGGACTTTGGGCCTGACCTGCTG
CTCACCCTGCTCTTCCTGCTCTTCCTGGCGCACGGGGTCACCTTGGACGGGGCCTCGGCC
AACCCCACTGTGTCCCTGCAGGAGTTCCTCATGGCCGAGCAGTCTCTGCCTGGCACGCTG
TTGAAGCTGGCGGCACAGGGGCTGGGCATGCAGGCCGCCTGCACCCTGATGCGCCTCTGC
TGGGCCTGGGAGCTCAGTGACCTGCACCTGCTGCAGAGCCTCATGGCCCAGAGCTGCAGC
TCGGCCCTGCGCACATCCGTGCCCCACGGGGCGCTTGTGGAGGCCGCCTGCGCCTTTTGT
TTCCATCTGACCCTCCTGCACCTGCGGCACAGTCCTCCCGCCTACAGCGGGCCCGCTGTG
GCTCTGTTGGTCACCGTCACGGCCTACACGGCCGGGCCCTTCACGTCTGCCTTCTTCAAC
CCTGCCCTGGCCGCCTCTGTGACCTTTGCCTGCTCGGGACACACCTTACTGGAGTACGTG
CAGGTGTACTGGCTGGGCCCTCTGACAGGGATGGTCCTGGCTGTGCTGCTGCACCAGGGC
CGCCTTCCCCACCTTTTCCAGAGGAACCTGTTCTACGGCCAGAAGAACAAGTACCGAGCA
CCCCGAGGGAAGCCGGCCCCGGCCTCAGGGGACACCCAGACCCCTGCAAAGGGGTCCAGT
GTCCGGGAGCCTGGGCGCAGTGGTGTTGAGGGGCCACATTCCAGCTGA
GenBank Gene IDNot Available
GeneCard IDNot Available
GenAtlas IDNot Available
HGNC IDHGNC:19941
Chromosome Location2
LocusNot Available
References
  1. Itoh T, Rai T, Kuwahara M, Ko SB, Uchida S, Sasaki S, Ishibashi K: Identification of a novel aquaporin, AQP12, expressed in pancreatic acinar cells. Biochem Biophys Res Commun. 2005 May 13;330(3):832-8. 15809071