NameKinesin-like protein KIF2B
SynonymsNot Available
Gene NameKIF2B
OrganismHuman
Amino acid sequence
>lcl|BSEQ0017705|Kinesin-like protein KIF2B
MASQFCLPESPCLSPLKPLKPHFGDIQEGIYVAIQRSDKRIHLAVVTEINRENYWVTVEW
VEKAVKKGKKIDLETILLLNPALDSAEHPMPPPPLSPLALAPSSAIRDQRTATKWVAMIP
QKNQTASGDSLDVRVPSKPCLMKQKKSPCLWEIQKLQEQREKRRRLQQEIRARRALDVNT
RNPNYEIMHMIEEYRRHLDSSKISVLEPPQEHRICVCVRKRPLNQRETTLKDLDIITVPS
DNVVMVHESKQKVDLTRYLQNQTFCFDHAFDDKASNELVYQFTAQPLVESIFRKGMATCF
AYGQTGSGKTYTMGGDFSGTAQDCSKGIYALVAQDVFLLLRNSTYEKLDLKVYGTFFEIY
GGKVYDLLNWKKKLQVLEDGNQQIQVVGLQEKEVCCVEEVLNLVEIGNSCRTSRQTPVNA
HSSRSHAVFQIILKSGRIMHGKFSLVDLAGNERGADTTKASRKRQLEGAEINKSLLALKE
CILALGQNKPHTPFRASKLTLVLRDSFIGQNSSTCMIATISPGMTSCENTLNTLRYANRV
KKLNVDVRPYHRGHYPIGHEAPRMLKSHIGNSEMSLQRDEFIKIPYVQSEEQKEIEEVET
LPTLLGKDTTISGKGSSQWLENIQERAGGVHHDIDFCIARSLSILEQKIDALTEIQKKLK
LLLADLHVKSKVE
Number of residues673
Molecular Weight76253.17
Theoretical pINot Available
GO Classification
Functions
  • ATP binding
  • ATPase activity
  • microtubule motor activity
Processes
  • mitotic nuclear division
  • antigen processing and presentation of exogenous peptide antigen via MHC class II
  • mitotic cell cycle
  • microtubule-based movement
  • microtubule depolymerization
  • regulation of chromosome segregation
  • blood coagulation
  • small GTPase mediated signal transduction
  • cell division
Components
  • nucleolus
  • microtubule organizing center
  • kinesin complex
  • spindle
  • condensed chromosome kinetochore
  • microtubule cytoskeleton
  • microtubule
  • nucleus
  • cytosol
General FunctionMicrotubule motor activity
Specific FunctionPlus end-directed microtubule-dependent motor required for spindle assembly and chromosome movement. Has microtubule depolymerization activity.
Pfam Domain Function
Transmembrane RegionsNot Available
GenBank Protein IDNot Available
UniProtKB IDQ8N4N8
UniProtKB Entry NameKIF2B_HUMAN
Cellular LocationCytoplasm
Gene sequence
>lcl|BSEQ0017706|Kinesin-like protein KIF2B (KIF2B)
ATGGCCAGCCAGTTCTGCCTCCCTGAATCCCCATGTCTCTCGCCCCTGAAACCCTTGAAG
CCACATTTCGGAGACATCCAAGAGGGCATCTACGTGGCGATCCAGCGCAGTGACAAGCGG
ATCCACCTCGCTGTGGTCACGGAGATCAACAGAGAAAACTATTGGGTCACGGTAGAGTGG
GTGGAGAAAGCAGTCAAAAAAGGCAAGAAGATTGACCTGGAGACCATACTCCTGCTGAAT
CCAGCTCTGGACTCTGCTGAACACCCCATGCCGCCCCCGCCCTTATCCCCCTTGGCTCTG
GCGCCCTCTTCGGCCATCAGGGACCAGCGTACCGCCACGAAATGGGTTGCGATGATCCCC
CAGAAAAACCAAACAGCCTCAGGGGACAGCCTGGATGTGAGGGTCCCCAGCAAACCTTGT
CTGATGAAGCAGAAAAAGTCTCCCTGCCTCTGGGAAATCCAGAAACTGCAGGAGCAGCGG
GAAAAGCGCAGGCGGCTGCAGCAGGAGATCCGAGCTAGACGCGCCCTCGATGTCAATACC
AGAAACCCCAACTACGAAATCATGCACATGATCGAAGAGTATCGCAGGCACCTGGACAGC
AGCAAGATCTCAGTCCTGGAGCCCCCGCAAGAACATCGCATCTGCGTCTGCGTGAGGAAG
CGGCCTCTCAACCAGCGAGAGACAACCTTAAAGGACCTGGATATCATCACCGTCCCCTCG
GACAATGTGGTTATGGTGCATGAGTCCAAGCAAAAGGTGGACCTCACTCGCTACCTGCAG
AACCAGACCTTCTGCTTCGACCATGCCTTCGATGACAAAGCCTCCAACGAGTTGGTGTAC
CAGTTCACCGCCCAGCCACTGGTGGAGTCCATCTTCCGCAAGGGCATGGCCACCTGCTTT
GCCTATGGGCAGACGGGAAGTGGGAAGACGTACACCATGGGTGGAGACTTTTCAGGAACG
GCCCAAGATTGTTCTAAGGGCATTTATGCTCTGGTGGCACAGGATGTCTTTCTCCTGCTC
AGAAACTCCACATATGAGAAGCTGGACCTCAAAGTCTATGGGACATTTTTTGAGATTTAT
GGGGGCAAGGTGTATGATTTGTTGAACTGGAAGAAGAAGCTGCAAGTCCTTGAGGATGGC
AATCAGCAAATCCAAGTGGTCGGGCTGCAGGAGAAAGAGGTGTGTTGTGTGGAGGAAGTG
CTGAACCTGGTGGAAATAGGGAATAGCTGTCGGACTTCCAGGCAAACACCTGTCAACGCT
CACTCATCCAGGAGCCATGCAGTGTTCCAGATCATCCTGAAGTCAGGACGGATAATGCAT
GGCAAGTTTTCCCTCGTTGATTTAGCTGGGAATGAAAGAGGAGCAGATACAACCAAGGCC
AGCCGGAAAAGGCAGCTGGAAGGGGCAGAGATTAACAAGAGTCTTCTAGCCCTCAAAGAA
TGTATTCTGGCTTTGGGTCAGAACAAGCCTCACACCCCATTCAGAGCCAGCAAACTCACA
CTGGTGCTCCGGGACTCCTTTATAGGCCAGAACTCCTCCACTTGCATGATTGCTACCATC
TCTCCGGGGATGACCTCTTGTGAAAACACTCTCAACACTTTAAGATATGCAAACAGAGTA
AAAAAATTAAATGTAGATGTAAGGCCCTACCATCGTGGCCACTATCCGATTGGACATGAG
GCACCAAGGATGTTAAAAAGTCACATCGGAAATTCAGAAATGTCCCTTCAGAGGGATGAA
TTTATTAAAATACCTTATGTACAGAGTGAGGAGCAGAAAGAGATTGAAGAGGTTGAAACA
TTACCCACTCTGTTAGGGAAGGATACCACAATTTCAGGGAAGGGATCTAGCCAATGGCTG
GAAAACATCCAGGAGAGAGCTGGTGGAGTACACCATGATATTGATTTTTGCATTGCCCGG
TCTTTGTCCATTTTGGAGCAGAAAATTGATGCTCTGACCGAGATCCAAAAGAAACTGAAA
TTATTACTAGCTGACCTCCACGTGAAGAGCAAGGTAGAGTGA
GenBank Gene IDNot Available
GeneCard IDNot Available
GenAtlas IDNot Available
HGNC IDHGNC:29443
Chromosome Location17
LocusNot Available
References
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