NameKinesin-like protein KIF26A
Synonyms
  • KIAA1236
Gene NameKIF26A
OrganismHuman
Amino acid sequence
>lcl|BSEQ0009144|Kinesin-like protein KIF26A
MVGRGVPLCAAQPAVAEGGPAREPPPLLEVSPRKRLPAGPDQDPCGSRPAPEGAGAGPEQ
GHSAGGGGWCRHCHTKLVELKRQAWKLVSGPGTTLRDPCLSALLLDKLPAPGALPACRPE
AERRCDVCATHLQQLTREAMHLLQAPASHEDLDAPHGGPSLAPPSTTTSSRDTPGPAGPA
GRQPGRAGPDRTKGLAWSPGPSVQVSVAPAGLGGALSTVTIQAQQCLEGMWSVSRVNSFL
PPACLAEAAVAAVAVADTVRECPPVAGPDGLSKAWGRGGVCTSALVTPTPGSVGGSTGPS
AAASFFIRAMQKLSLASKRKKPHPPPPPATRGTSTYPTDFSGVLQLWPPPAPPCLLRAAS
KTKDNPGSIGKVKVMLRIWPAQGAQRSAEAMSFLKVDPRKKQVILYDPAAGPPGSAGPRR
AATAAVPKMFAFDAVFPQDSEQAEVCSGTVADVLQSVVSGADGCIFSFGHMSLGKSYTMI
GKDSSPQSLGIVPCAISWLFRLIEERRERTGTRFSVRVSAVEVCGRDQSLRDLLAEVAPG
SLQDTQSPGVYLREDPVCGAQLQNQSELRAPTAEKAAFYLDAALAARSTSRAGCGEDARR
SSHMLFTLHVYQYRMEKCGRGGMSGGRSRLHLIDLGSCEAAAGRAGEAAGGPLCLSLSAL
GSVILALVNGAKHVPYRDHRLTMLLRESLATAGCRTTMIAHVSDAPAQHAETLSTVQLAA
RIHRLRRKKAKYASSSSGGESSCEEGRARRPPHLRPFHPRTVALDPDRTPPCLPGDPDYS
SSSEQSCDTVIYVGPGGAALSDRELTDNEGPPDFVPIIPALSRHRPSKGPRDADHFRCST
FAELQERLECMDGNEGPSGGPGGTDGAQASPARGGRKPSPPEAASPRKAVGTPMAASTPR
GSSGPDTHQGTPEPCKAIVWGDQREDSSAWPELLVPEKAAVSGGRRPLPSPAPPPPQLLE
ACRAPEEPGGGGTDGVARTPPVGMSGQVAGSPMLPGATCPRLAAGSRCPERGLLTTTVTL
QRPVELNGEDELVFTVVEELSLGALAGAGRPTSLASFDSDCSLRALASGSRPVSIISSIN
DEFDAYTSQAPEGGPLEGAAWAGSSHGSSISSWLSEVSVCTADSRDPTPQPRFSPDSLAG
LDPGGPPALDGSLGDGSSGFLGPDRPDSPGPTWGPCPGEVAAVAPSRPGREPQAGPSRWA
SAAQTIHSSLPRKPRTASATTRVGCARLGQSPPGRGGLFEDPWLLRVGECDTQAASAGRA
PSPTLGSPRLPEAQVMLACAQRVVDGCEVAARAARRPEAVARIPPLRRGATTLGVTTPAV
SWGDAPTEVVACSGSLKASPTSKKGLAPKAGFLPRPSGAAPPAPPTRKSSLEQRSSPASA
PPHAVNPARVGAAAVLRGEEEPRPSSRADHSVPRATSSLKARASKVEAAHRLAGHASLER
YEGLAHSSSKGREAPGRPPRAVPKLGVPPSSPTHGPAPACRSGAAKAVGAPKPPVGGGKG
RGLVAGGSRALGPSVKLSTASVTGRSPGGPVAGPRAAPRAGPSVGAKAGRGTVMGTKQAL
RAAHSRVHELSASGAPGRGGSSWGSADSDSGHDSGVNVGEERPPTGPALPSPYSKVTAPR
RPQRYSSGHGSDNSSVLSGELPPAMGRTALFHHSGGSSGYESLRRDSEATGSASSAPDSM
SESGAASPGARTRSLKSPKKRATGLQRRRLIPAPLPDTTALGRKPSLPGQWVDLPPPLAG
SLKEPFEIKVYEIDDVERLQRPRPTPREAPTQGLACVSTRLRLAERRQQRLREVQAKHKH
LCEELAETQGRLMLEPGRWLEQFEVDPELEPESAEYLAALERATAALEQCVNLCKAHVMM
VTCFDISVAASAAIPGPQEVDV
Number of residues1882
Molecular Weight194587.415
Theoretical pINot Available
GO Classification
Functions
  • microtubule motor activity
  • microtubule binding
  • ATP binding
Processes
  • blood coagulation
  • antigen processing and presentation of exogenous peptide antigen via MHC class II
  • negative regulation of signal transduction
  • enteric nervous system development
  • regulation of cell growth by extracellular stimulus
  • microtubule-based movement
Components
  • cytosol
  • kinesin complex
  • microtubule
General FunctionMicrotubule motor activity
Specific FunctionAtypical kinesin that plays a key role in enteric neuron development. Acts by repressing a cell growth signaling pathway in the enteric nervous system development, possibly via its interaction with GRB2 that prevents GRB2-binding to SHC, thereby attenating the GDNF-Ret signaling. Binds to microtubules but lacks microtubule-based motility due to the absence of ATPase activity (By similarity).
Pfam Domain Function
Transmembrane RegionsNot Available
GenBank Protein IDNot Available
UniProtKB IDQ9ULI4
UniProtKB Entry NameKI26A_HUMAN
Cellular LocationCytoplasm
Gene sequence
>lcl|BSEQ0013638|Kinesin-like protein KIF26A (KIF26A)
ATGGTCGGCCGCGGCGTCCCTCTGTGCGCTGCGCAGCCCGCGGTGGCCGAGGGCGGCCCG
GCCCGCGAGCCGCCGCCGCTGCTGGAGGTGTCCCCCCGAAAGAGGCTACCCGCCGGGCCC
GACCAGGACCCATGCGGCAGCCGCCCTGCTCCCGAAGGCGCCGGGGCCGGCCCAGAGCAG
GGCCACTCGGCCGGCGGAGGCGGCTGGTGCCGCCACTGCCACACGAAGCTGGTGGAGCTC
AAGCGACAGGCGTGGAAGCTGGTCAGCGGGCCCGGGACCACCCTCCGGGATCCTTGCCTC
TCTGCCCTGCTTCTCGACAAGCTACCAGCACCTGGGGCCCTGCCAGCCTGTCGCCCAGAG
GCCGAGCGCCGCTGTGACGTCTGCGCCACACACCTGCAGCAGCTCACACGGGAGGCCATG
CACCTGCTGCAGGCCCCTGCCAGCCATGAGGACCTTGACGCCCCCCATGGAGGCCCCAGC
CTCGCACCCCCCAGCACCACGACCAGCTCGAGGGACACGCCAGGACCAGCGGGTCCTGCA
GGGAGGCAGCCAGGACGAGCTGGGCCAGACAGGACCAAGGGGCTGGCCTGGTCCCCCGGG
CCCAGTGTCCAGGTGTCTGTAGCACCTGCGGGTCTTGGAGGGGCGCTGAGCACGGTCACC
ATCCAGGCCCAGCAGTGCCTGGAGGGCATGTGGAGTGTCTCGCGGGTCAACAGCTTCCTC
CCGCCGGCGTGCCTGGCCGAGGCAGCGGTGGCGGCCGTGGCGGTGGCAGACACGGTCCGA
GAATGCCCCCCCGTGGCCGGCCCTGATGGCTTGTCGAAGGCCTGGGGCCGTGGTGGAGTC
TGCACGTCAGCCCTGGTCACCCCCACCCCGGGCTCGGTGGGGGGCTCCACAGGCCCCTCA
GCTGCAGCCTCCTTCTTCATAAGGGCTATGCAGAAGCTCAGCCTGGCCTCCAAGAGGAAG
AAGCCCCACCCGCCACCGCCTCCAGCCACCCGCGGCACCTCCACCTACCCCACCGACTTC
AGCGGGGTCCTGCAGCTGTGGCCGCCCCCGGCGCCCCCCTGCCTGCTCAGGGCCGCCTCC
AAGACCAAGGACAACCCTGGCAGCATCGGGAAGGTGAAGGTTATGCTGCGGATCTGGCCC
GCACAGGGGGCCCAGCGCTCGGCCGAGGCCATGTCCTTCCTGAAGGTGGACCCTCGGAAG
AAGCAGGTGATCCTCTACGATCCCGCCGCCGGTCCCCCAGGCAGCGCAGGCCCCCGGCGA
GCCGCCACTGCTGCAGTTCCCAAGATGTTTGCCTTCGATGCCGTCTTCCCCCAGGACTCC
GAGCAGGCCGAAGTCTGCTCGGGGACCGTGGCCGACGTGCTCCAGTCGGTGGTCAGTGGG
GCTGATGGCTGCATTTTTTCCTTTGGCCACATGAGCCTGGGCAAGTCGTACACCATGATC
GGGAAGGACAGCTCACCCCAGAGCCTGGGCATCGTGCCCTGCGCCATCTCCTGGCTCTTC
AGGCTCATCGAGGAGCGCAGGGAGAGGACGGGCACCCGCTTCTCCGTCCGGGTCTCAGCC
GTGGAGGTGTGCGGGCGCGACCAGAGCCTGCGGGACCTGCTGGCCGAGGTGGCCCCTGGC
AGCCTCCAGGACACCCAGTCTCCGGGAGTGTACCTGCGGGAGGACCCCGTGTGTGGGGCG
CAGCTCCAGAACCAAAGCGAGCTGCGGGCACCCACGGCCGAGAAGGCGGCTTTCTACCTG
GATGCGGCCCTGGCGGCCCGCAGCACCAGCCGAGCGGGCTGTGGCGAGGACGCCCGACGC
AGCTCCCACATGTTGTTCACGCTGCACGTCTACCAGTACCGCATGGAGAAGTGCGGCCGG
GGAGGAATGTCCGGAGGCCGCAGCCGCCTGCACCTCATCGACCTGGGCAGCTGTGAGGCG
GCGGCTGGCAGGGCCGGGGAGGCTGCTGGGGGTCCCCTGTGTCTGTCCCTGTCGGCCCTG
GGCAGCGTCATCTTGGCCCTGGTCAACGGAGCCAAGCATGTGCCGTATCGGGACCACAGG
CTCACCATGCTGCTGCGTGAATCCCTGGCCACCGCTGGCTGCCGCACCACCATGATCGCC
CACGTGTCGGATGCGCCAGCCCAGCACGCAGAGACACTCAGCACCGTGCAGCTCGCCGCC
CGCATCCACCGCCTGCGCAGGAAGAAGGCCAAGTACGCCTCCAGCTCCTCTGGCGGGGAG
AGCTCCTGTGAGGAAGGCCGGGCCCGTCGGCCCCCGCACCTGCGGCCCTTCCACCCACGC
ACTGTGGCCCTGGACCCCGACCGCACGCCTCCCTGCCTGCCCGGTGACCCCGATTACTCC
TCCAGCAGCGAGCAGTCCTGTGACACGGTCATCTACGTGGGGCCCGGTGGGGCGGCGCTG
TCAGACCGGGAGCTCACCGACAACGAAGGTCCGCCTGACTTCGTGCCCATCATCCCTGCC
CTGAGCCGCCACCGGCCCTCCAAGGGTCCCCGAGACGCAGACCACTTCCGCTGCAGCACC
TTCGCGGAGCTGCAGGAGCGGCTGGAATGCATGGACGGCAACGAGGGTCCCTCAGGAGGT
CCAGGTGGCACCGACGGAGCTCAGGCCAGCCCCGCCCGAGGGGGCCGGAAGCCCTCGCCA
CCAGAGGCTGCATCCCCCAGGAAGGCCGTGGGCACCCCGATGGCTGCCAGCACCCCTCGA
GGCAGTTCTGGTCCAGACACCCACCAGGGTACCCCTGAGCCCTGCAAGGCCATTGTCTGG
GGTGACCAGAGAGAGGACAGCAGCGCTTGGCCTGAGCTGCTGGTCCCGGAAAAGGCTGCA
GTGAGTGGAGGCAGGAGGCCACTGCCCAGCCCGGCTCCCCCACCTCCTCAGTTGCTGGAA
GCCTGCAGAGCCCCAGAAGAGCCTGGGGGAGGGGGCACTGATGGAGTGGCACGGACCCCT
CCCGTGGGCATGAGTGGGCAGGTGGCTGGGTCCCCGATGCTTCCTGGGGCCACCTGCCCC
CGCCTGGCTGCTGGCAGTCGCTGTCCGGAGCGGGGCCTGCTCACCACCACAGTGACCCTG
CAGCGGCCAGTGGAGCTCAACGGCGAGGACGAGCTGGTGTTCACGGTGGTGGAGGAGCTG
TCCCTGGGGGCGCTTGCCGGAGCTGGGCGGCCCACCAGCCTGGCTAGCTTCGACAGTGAC
TGCTCCCTGCGGGCCCTGGCCTCGGGGTCCCGGCCAGTCAGCATCATCAGCAGCATCAAT
GATGAGTTTGACGCCTACACCTCTCAGGCCCCTGAGGGGGGGCCCCTGGAGGGGGCAGCC
TGGGCCGGCAGCAGTCACGGCTCCTCCATCAGCTCCTGGCTCAGCGAGGTCAGCGTCTGC
ACTGCCGACAGCCGTGACCCCACGCCGCAGCCCCGCTTCAGCCCCGACTCGCTGGCAGGG
CTTGACCCTGGGGGCCCCCCTGCCCTGGATGGTTCCCTGGGGGATGGAAGCTCTGGGTTC
CTGGGGCCAGACAGACCTGACAGTCCTGGGCCAACCTGGGGTCCGTGCCCTGGGGAAGTG
GCTGCAGTGGCCCCATCCCGACCCGGCAGGGAGCCCCAGGCCGGGCCCTCGCGGTGGGCA
TCCGCAGCCCAGACCATCCACTCCAGCCTCCCCCGGAAACCGAGGACTGCCTCTGCCACC
ACCCGTGTGGGCTGTGCTCGCCTGGGCCAGAGCCCACCTGGCCGTGGAGGCCTGTTTGAG
GACCCATGGCTGCTCCGGGTAGGGGAGTGTGATACCCAGGCAGCTTCTGCTGGCAGGGCC
CCCAGCCCCACACTTGGCTCCCCCCGGCTGCCTGAGGCCCAGGTGATGCTAGCCTGTGCC
CAGAGAGTGGTGGACGGGTGTGAGGTGGCAGCCAGGGCGGCCCGCAGGCCAGAGGCTGTG
GCTCGGATCCCACCGCTGCGGAGGGGTGCCACCACGCTGGGTGTGACAACGCCAGCTGTG
TCCTGGGGAGATGCTCCCACGGAGGTGGTGGCCTGCTCGGGGAGCCTGAAGGCCTCCCCC
ACCAGCAAGAAGGGTCTGGCTCCCAAGGCGGGCTTCCTCCCGAGGCCCAGTGGGGCGGCC
CCCCCGGCCCCACCCACGCGGAAGTCCAGCCTGGAGCAGAGGAGCAGCCCGGCCTCGGCC
CCTCCGCATGCTGTGAACCCGGCGCGGGTCGGGGCTGCTGCTGTCCTTCGAGGGGAGGAG
GAGCCCAGACCCAGCAGCCGGGCTGACCACTCTGTCCCCAGGGCCACGTCCAGCCTGAAG
GCCCGGGCCAGCAAGGTAGAAGCAGCACACCGTCTTGCCGGACACGCGTCTCTGGAGCGG
TACGAAGGCCTGGCGCACAGCAGCAGCAAGGGCCGGGAAGCCCCTGGGCGGCCTCCCCGG
GCTGTACCCAAGCTGGGTGTGCCACCCTCCAGCCCCACACACGGTCCAGCTCCCGCCTGT
AGGAGCGGCGCAGCCAAGGCTGTGGGGGCCCCCAAGCCCCCTGTTGGTGGAGGCAAGGGC
CGTGGCCTAGTGGCTGGTGGGTCGCGGGCTCTGGGGCCTTCGGTGAAGCTGTCTACGGCC
TCTGTGACGGGCAGGAGCCCTGGCGGCCCTGTGGCCGGTCCCAGAGCAGCCCCACGGGCC
GGGCCCAGTGTCGGGGCGAAGGCTGGCCGGGGTACCGTCATGGGCACAAAGCAGGCGCTC
CGGGCTGCTCACAGCCGCGTCCATGAGCTGTCAGCCAGTGGAGCCCCGGGCCGAGGTGGC
TCCTCGTGGGGCTCGGCGGACTCAGACAGCGGCCATGACAGCGGCGTGAACGTGGGGGAG
GAGCGGCCACCCACGGGCCCGGCCCTGCCCTCCCCCTACAGCAAGGTGACCGCCCCACGG
CGGCCCCAGCGCTACAGCAGCGGCCATGGCAGCGACAACAGCAGCGTGCTGAGTGGAGAG
CTGCCGCCCGCCATGGGCCGCACCGCCCTTTTCCACCACAGCGGTGGCAGCAGTGGCTAT
GAGAGCCTGCGGCGCGACAGCGAGGCCACCGGCAGCGCCTCCTCCGCCCCTGACTCCATG
AGCGAGAGTGGGGCTGCCTCCCCAGGCGCCCGCACCCGCAGCCTCAAGTCCCCCAAGAAG
AGGGCCACAGGTCTGCAGCGGCGGCGCCTGATTCCCGCCCCACTGCCCGACACCACTGCC
CTGGGCCGTAAGCCCAGCCTCCCCGGGCAGTGGGTGGACCTGCCCCCGCCCCTGGCTGGC
TCCCTGAAGGAGCCGTTCGAGATCAAGGTGTACGAGATCGATGACGTGGAGCGCCTTCAG
CGGCCCCGCCCCACCCCGAGGGAGGCCCCCACCCAGGGTCTGGCGTGCGTCAGTACAAGG
CTGCGGCTGGCGGAGCGCAGGCAGCAGCGGCTGCGGGAGGTGCAGGCCAAGCACAAGCAC
CTGTGTGAGGAGCTGGCCGAGACCCAGGGCCGGCTGATGCTGGAGCCTGGCCGCTGGCTG
GAGCAGTTTGAGGTGGACCCGGAGCTGGAGCCCGAGTCGGCCGAGTACCTGGCGGCCCTG
GAGCGAGCCACGGCGGCCCTGGAGCAGTGCGTGAACCTGTGCAAGGCGCACGTCATGATG
GTCACCTGCTTCGACATCAGCGTTGCAGCCAGTGCTGCCATCCCGGGGCCGCAGGAGGTG
GACGTCTGA
GenBank Gene IDNot Available
GeneCard IDNot Available
GenAtlas IDNot Available
HGNC IDHGNC:20226
Chromosome Location14
LocusNot Available
References
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