Browsing Toxins By Category
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D2466 | Ciguatoxin 4B 123676-76-6 | C60H84O16 1061.299 g/mol |  |
| Ciguatoxin lowers the threshold for opening voltage-gated sodium channels in synapses of the nervous system. The effect of opening a sodium channel will cause depolari...more Number of Targets: 14 |
| T3D2464 | Ciguatoxin 2 142185-85-1 | C60H86O18 1095.314 g/mol |  |
| Ciguatoxin lowers the threshold for opening voltage-gated sodium channels in synapses of the nervous system. The effect of opening a sodium channel will cause depolari...more Number of Targets: 14 |
| T3D2465 | 54-Deoxyciguatoxin 139341-09-6 | C60H86O18 1095.314 g/mol |  |
| Ciguatoxin lowers the threshold for opening voltage-gated sodium channels in synapses of the nervous system. The effect of opening a sodium channel will cause depolari...more Number of Targets: 14 |
| T3D2463 | Ciguatoxin 1 11050-21-8 | C60H86O19 1111.313 g/mol |  |
| Ciguatoxin lowers the threshold for opening voltage-gated sodium channels in synapses of the nervous system. The effect of opening a sodium channel will cause depolari...more Number of Targets: 14 |
| T3D2487 | Apamin (Apis mellifera) 24345-16-2 | Not Available 5223.305 g/mol |  |
| Apamin binds to the SK channels (small conductance Ca2+-activated K+ channels) in the brain and spinal cord and inhibits them, likely by acting as a pore blocker. Inhi...more Number of Targets: 3 |
| T3D2512 | Iberiotoxin 129203-60-7 | Not Available 4253.920 g/mol |  |
| Iberiotoxin binds to the outer face of the large-conductance calcium-activated potassium channels with high affinity. It selectively inhibits the current by decreasin...more Number of Targets: 5 |
| T3D2462 | Palytoxin 77734-91-9 | C129H223N3O53 2664.139 g/mol |  |
| Palytoxin targets the sodium-potassium pump protein by binding to the molecule such that the molecule is locked in a position where it allows passive transport of both...more Number of Targets: 9 |
| T3D2587 | Maitotoxin 59392-53-9 | C164H256Na2O68S2 3425.856 g/mol |  |
| Maitotoxin activates calcium permeable, non-selective cation channels, leading to an increase in levels of cytosolic calcium ions. It is thought that maitotoxin leads ...more Number of Targets: 0 |