Browsing Toxins
Displaying toxin 3026 - 3050 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D0804 | 2-Methyl-4-chlorophenoxyacetic acid 94-74-6 | C9H9ClO3 200.619 g/mol |  |
| CDDs cause their toxic effects by binding to the aryl hydrocarbon receptor and subsequently altering the trascription of certain genes. The affinity for the Ah recepto...more Number of Targets: 6 |
| T3D3460 | 2-Methyl-2-butene 513-35-9 | C5H10 70.133 g/mol |  |
| Petroleum distillates are central nervous system depressants and cause pulmonary damage. (A600) Number of Targets: 0 |
| T3D3462 | 2-Methyl-1-butene 563-46-2 | C5H10 70.133 g/mol |  |
| Petroleum distillates are central nervous system depressants and cause pulmonary damage. (A600) Number of Targets: 0 |
| T3D3230 | 2-Methoxy-4-propylphenol 2785-87-7 | C10H14O2 166.217 g/mol |  |
| Dihydroeugenol may cause allergic contact dermatitis via two different mechanisms: The poison ivy and the phenolic radical mechanisms (A2445). Number of Targets: 1 |
| T3D0977 | 2-Isopropylphenyl methylcarbamate 2631-40-5 | C11H15NO2 193.242 g/mol |  |
| 2-Isopropylphenyl methylcarbamate is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carbamoylat...more Number of Targets: 2 |
| T3D3945 | 2-Isopropylphenol 88-69-7 | C9H12O 136.191 g/mol |  |
| Not Available Number of Targets: 2 |
| T3D0898 | 2-Hydroxyphenyl methylcarbamate 10309-97-4 | C8H9NO3 167.162 g/mol |  |
| 2-Hydroxyphenyl methylcarbamate is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carbamoylatio...more Number of Targets: 2 |
| T3D4993 | 2-hydroxyflutamide 52806-53-8 | C11H11F3N2O4 292.211 g/mol |  |
| Hydroxyflutamide is an antiandrogen. Antiandrogens alter the androgen pathway by blocking the appropriate receptors, competing for binding sites on the cell's surface,...more Number of Targets: 0 |
| T3D4892 | 2-Hydroxybenzaldehyde 90-02-8 | C7H6O2 122.121 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D4258 | 2-Hydroxyadipic acid 18294-85-4 | C6H10O5 162.141 g/mol |  |
| 2-Hydroxyadipic acid is a hydroxy-dicarboxylic acid formed by the reduction of 2-ketoadipic acid. Deficiency of 2-ketoadipic dehydrogenase causes 2-ketoadipic acidemia...more Number of Targets: 0 |
| T3D4189 | 2-Hexenal 505-57-7 | C6H10O 98.143 g/mol |  |
| Uremic toxins such as 2-Hexenal are actively transported into the kidneys via organic ion transporters (especially OAT3). Increased levels of uremic toxins can stimula...more Number of Targets: 4 |
| T3D4190 | 2-Heptenal 2463-63-0 | C7H12O 112.170 g/mol |  |
| Uremic toxins such as 2-Heptenal are actively transported into the kidneys via organic ion transporters (especially OAT3). Increased levels of uremic toxins can stimul...more Number of Targets: 3 |
| T3D4938 | 2-Ethylhexanoic acid 149-57-5 | C8H16O2 144.211 g/mol |  |
| Not Available Number of Targets: 2 |
| T3D4885 | 2-Ethyl-1-hexanol sulfate 126-92-1 | C8H18O4S 210.291 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D4943 | 2-Ethoxyethanol 110-80-5 | C4H10O2 90.121 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D0897 | 2-Cyclopentylphenyl methylcarbamate 3282-00-6 | C13H17NO2 219.280 g/mol |  |
| 2-Cyclopentylphenyl methylcarbamate is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carbamoyl...more Number of Targets: 2 |
| T3D0245 | 2-Chlorophenol 95-57-8 | C6H5ClO 128.556 g/mol |  |
| 2-chlorophenol works as a weak uncoupler of oxidative phosphorylation and inhibitors of cellular respiration. The ability of chlorophenols to uncouple oxidative phosph...more Number of Targets: 5 |
| T3D2268 | 2-Chlorodibenzofuran 51230-49-0 | C12H7ClO 202.636 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2047 | 2-Chlorodibenzo-p-dioxin 39227-54-8 | C12H7ClO2 218.636 g/mol |  |
| CDDs cause their toxic effects by binding to the aryl hydrocarbon receptor and subsequently altering the trascription of certain genes. The affinity for the Ah recepto...more Number of Targets: 4 |
| T3D0390 | 2-Chlorobiphenyl 2051-60-7 | C12H9Cl 188.653 g/mol |  |
| The mechanism of action varies with the specific PCB. Dioxin-like PCBs bind to the aryl hydrocarbon receptor, which disrupts cell function by altering the transcriptio...more Number of Targets: 8 |
| T3D4660 | 2-Chlorobenzylidene malononitrile 2698-41-1 | C10H5ClN2 188.613 g/mol |  |
| Organic nitriles decompose into cyanide ions both in vivo and in vitro. Consequently the primary mechanism of toxicity for organic nitriles is their production of toxi...more Number of Targets: 1 |
| T3D0896 | 2-Chloro-4,5-xylyl N-hydroxy-N-methylcarbamate 14357-82-5 | C10H12ClNO3 229.660 g/mol |  |
| 2-Chloro-4,5-xylyl N-hydroxy-N-methylcarbamate is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases b...more Number of Targets: 2 |
| T3D1788 | 2-Bromopropane 75-26-3 | C3H7Br 122.992 g/mol |  |
| Organobromide compounds, especially alkylbromides are strong alkylating agents. Consequently they can randomly modify the surfaces of proteins and lipids, leading to ...more Number of Targets: 3 |
| T3D1773 | 2-Bromohexane 3377-86-4 | C6H13Br 165.071 g/mol |  |
| Bromine is a powerful oxidizing agent and is able to release oxygen free radicals from the water in mucous membranes. These free radicals are also potent oxidizers and...more Number of Targets: 0 |
| T3D2266 | 2-Bromodibenzofuran 86-76-0 | C12H7BrO 247.087 g/mol |  |
| As a strong lachrymator, one of the most probable protein targets is the TRPA1 ion channel that is expressed in sensory nerves (trigeminal nerve) of the eyes, nose, mo...more Number of Targets: 2 |