Browsing Toxins
Displaying toxin 3126 - 3150 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D4209 | Acetamide 60-35-5 | C2H5NO 59.067 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D4212 | Safrole 94-59-7 | C10H10O2 162.185 g/mol |  |
| Not Available Number of Targets: 2 |
| T3D4213 | 2-Aminonaphthalene 91-59-8 | C10H9N 143.185 g/mol |  |
| Not Available Number of Targets: 3 |
| T3D4214 | Diethylamine 71247-25-1 | C4H11N 73.137 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D4215 | N'-nitrosonornicotine 16543-55-8 | C9H11N3O 177.203 g/mol |  |
| Not Available Number of Targets: 3 |
| T3D4216 | Nitrobenzene 98-95-3 | C6H5NO2 123.109 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D4217 | O-Toluidine 95-53-4 | C7H9N 107.153 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D4218 | 2,6-Dimethylaniline 87-62-7 | C8H11N 121.180 g/mol |  |
| Treatment of AS52 cells with N-OH-2,6-dimethylaniline (2,6-DMA) and 2,6-DMAP led to intracellular production of reactive oxygen species (ROS). DNA strand breaks were o...more Number of Targets: 1 |
| T3D4224 | Glycidol 556-52-5 | C3H6O2 74.079 g/mol |  |
| Not Available Number of Targets: 2 |
| T3D4232 | Cylindrospermopsin 143545-90-8 | C15H21N5O7S 415.422 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D4234 | Lipopolysaccharide Not Available | C21H44NO9P 485.549 g/mol |  |
| Not Available Number of Targets: 0 |
| T3D4235 | Aplysiatoxin 52659-57-1 | C32H47BrO10 671.614 g/mol |  |
| Aplysiatoxin is a 12-O-tetradecanoylphorbol-13-acetate (TPA)-type tumor promoter that activates protein kinase C (PKC) (A15358). In cancer cells, PKC isozymes are invo...more Number of Targets: 1 |
| T3D4237 | Fumaric acid 110-17-8 | C4H4O4 116.072 g/mol |  |
| Acute Toxicity: Fumarate is also an endogenous electrophile and reacts spontaneously with cysteine residues in proteins by a Michael addition reaction to form S-(2-suc...more Number of Targets: 17 |
| T3D4240 | Androstenedione 63-05-8 | C19H26O2 286.409 g/mol |  |
| Androstenedione is converted to testosterone and estrogen, and when taken in sufficient quantities androstenedione can cause unwanted masculinizing and feminizing effe...more Number of Targets: 11 |
| T3D4242 | Dehydroepiandrosterone sulfate 651-48-9 | C19H28O5S 368.488 g/mol |  |
| Although it predominantly functions as an endogenous precursor to more potent androgens such as testosterone and dihydroxytestosterone, DHEA (which is produced from DH...more Number of Targets: 0 |
| T3D4245 | Deoxycorticosterone 64-85-7 | C21H30O3 330.461 g/mol |  |
| Not Available Number of Targets: 6 |
| T3D4247 | L-2-Hydroxyglutaric acid 13095-48-2 | C5H8O5 148.114 g/mol |  |
| 2-hydroxyglutarate is an oncometabolite. It is a competitive inhibitor of multiple α-ketoglutarate-dependent dioxygenases, including histone demethylases and the TET f...more Number of Targets: 16 |
| T3D4250 | Gamma-Aminobutyric acid 56-12-2 | C4H9NO2 103.120 g/mol |  |
| Not Available Number of Targets: 10 |
| T3D4251 | D-2-Hydroxyglutaric acid 2889-31-8 | C5H8O5 148.114 g/mol |  |
| 2-hydroxyglutarate is an oncometabolite. It is a competitive inhibitor of multiple α-ketoglutarate-dependent dioxygenases, including histone demethylases and the TET f...more Number of Targets: 16 |
| T3D4253 | L-Lactic acid 79-33-4 | C3H6O3 90.078 g/mol |  |
| Accumulation of L-lactic acid in the body has been shown to be toxic. At times of lactic acidosis, when excess intracellular lactate is released into the blood, mainte...more Number of Targets: 1 |
| T3D4257 | Oxoadipic acid 3184-35-8 | C6H8O5 160.125 g/mol |  |
| In the matrix of mitochondria, 2-oxoadipate is decarboxylated to glutaryl-CoA by the 2-oxoadipate dehydrogenase complex and then converted to acetyl-CoA. Accumulation ...more Number of Targets: 1 |
| T3D4258 | 2-Hydroxyadipic acid 18294-85-4 | C6H10O5 162.141 g/mol |  |
| 2-Hydroxyadipic acid is a hydroxy-dicarboxylic acid formed by the reduction of 2-ketoadipic acid. Deficiency of 2-ketoadipic dehydrogenase causes 2-ketoadipic acidemia...more Number of Targets: 0 |
| T3D4259 | Aminoadipic acid 542-32-5 | C6H11NO4 161.156 g/mol |  |
| Not Available Number of Targets: 4 |
| T3D4262 | 3-Hydroxymethylglutaric acid 503-49-1 | C6H10O5 162.141 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D4263 | 3-Hydroxyisovaleric acid 625-08-1 | C5H10O3 118.131 g/mol |  |
| 3-Hydroxyisovaleric acid is a normal human metabolite excreted in the urine. Elevated levels of this compound are found in several disorders due to impairment of renal...more Number of Targets: 0 |