Browsing Toxins By Category
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D4237 | Fumaric acid 110-17-8 | C4H4O4 116.072 g/mol |  |
| Acute Toxicity: Fumarate is also an endogenous electrophile and reacts spontaneously with cysteine residues in proteins by a Michael addition reaction to form S-(2-suc...more Number of Targets: 17 |
| T3D4811 | Farnesol 4602-84-0 | C15H26O 222.366 g/mol |  |
| Not Available Number of Targets: 3 |
| T3D4461 | Ethylmalonic acid 601-75-2 | C5H8O4 132.115 g/mol |  |
| Ethylmalonic acid is identified in the urine of patients with short-chain acyl-coenzyme A dehydrogenase deficiency, which is a fatty acid metabolism disorder. Number of Targets: 1 |
| T3D4769 | Ethanolamine 141-43-5 | C2H7NO 61.083 g/mol |  |
| Not Available Number of Targets: 4 |
| T3D4746 | Estrone 53-16-7 | C18H22O2 270.366 g/mol |  |
| Estrogens enter the cells of responsive tissues (e.g. female organs, breasts, hypothalamus, pituitary) where they interact with estrogen receptors. Hormone-bound estro...more Number of Targets: 5 |
| T3D4790 | Estriol 50-27-1 | C18H24O3 288.381 g/mol |  |
| Estriol levels can be measured to give an indication of the general health of the fetus. DHEA-S is produced by the adrenal cortex of the fetus. This is converted to es...more Number of Targets: 4 |
| T3D4668 | Estradiol 50-28-2 | C18H24O2 272.382 g/mol |  |
| Estradiol enters target cells freely (e.g., female organs, breasts, hypothalamus, pituitary) and interacts with a target cell receptor. When the estrogen receptor has ...more Number of Targets: 8 |
| T3D2635 | Erabutoxin 59536-69-5 | Not Available 9136.510 g/mol |  |
| Erabutoxin binds with high affinity to muscular nicotinic acetylcholine receptors (nAChRs), and with low affinity to neuronal alpha-7 nAChRs. This produces peripheral ...more Number of Targets: 6 |
| T3D3962 | Equol 531-95-3 | C15H14O3 242.270 g/mol |  |
| Not Available Number of Targets: 2 |
| T3D2530 | Epibatidine 140111-52-0 | C11H13ClN2 208.687 g/mol |  |
| Epibatidine works by binding and activating nicotinic acetylcholine receptors. (L1074) Number of Targets: 17 |
| T3D3967 | Enterolactone 76543-15-2 | C18H18O4 298.333 g/mol |  |
| Not Available Number of Targets: 3 |
| T3D2549 | Eledoisin (Eledone cirrhosa) 69-25-0 | Not Available 1206.410 g/mol |  |
| Eledoisin is a tachykinin peptide. Tachykinins excite neurons, evoke behavioural responses, are potent vasodilators and secretagogues, and contract (directly or indire...more Number of Targets: 3 |
| T3D4300 | Dopamine 51-61-6 | C8H11NO2 153.178 g/mol |  |
| Dopamine is a precursor to norepinephrine in noradrenergic nerves and is also a neurotransmitter in certain areas of the central nervous system. Dopamine produces posi...more Number of Targets: 15 |
| T3D4040 | Domoic acid 14277-97-5 | C15H21NO6 311.330 g/mol |  |
| Domoic acid acts as a neurotoxin. It induces excitotoxicity by an integrative action on ionotropic glutamate receptors at both sides of the synapse for which it has hi...more Number of Targets: 1 |
| T3D2636 | Disintegrin echistatin (Echis carinatus) Not Available | Not Available 5424.090 g/mol |  |
| Disintegrins work by countering blood clotting steps, inhibiting the clumping of platelets. They inhibit fibrinogen interaction with platelet receptors expressed on gl...more Number of Targets: 2 |
| T3D4030 | Dinophysistoxin 1 81720-10-7 | C45H70O13 819.030 g/mol |  |
| Dinophysistoxin 1 (DTX1) is the analogue of okadaic acid causing diarrheic shellfish poisoning (DSP) in humans shortly after the ingestion of contaminated seafood. DTX...more Number of Targets: 0 |
| T3D0304 | Dimethylarsine 593-57-7 | C2H7As 105.999 g/mol |  |
| Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by co...more Number of Targets: 44 |
| T3D4333 | Dihydrouracil 504-07-4 | C4H6N2O2 114.103 g/mol |  |
| Not Available Number of Targets: 0 |
| T3D4332 | Dihydrothymine 696-04-8 | C5H8N2O2 128.129 g/mol |  |
| Dihydropyrimidine dehydrogenase catalyzes the reduction of thymine to 5, 6-dihydrothymine then dihydropyrimidinase hydrolyzes 5, 6-dihydrothymine to N-carbamyl-b-alani...more Number of Targets: 0 |
| T3D4751 | Dihydrotestosterone 521-18-6 | C19H30O2 290.440 g/mol |  |
| Not Available Number of Targets: 7 |
| T3D3958 | Diethylthiophosphate 5871-17-0 | C4H11O3PS 170.167 g/mol |  |
| Diethylthiophosphate (DETP) induces DNA damage only in the hepatic cell lines, and this effect could be related to a secondary non-diffusible metabolite generated by t...more Number of Targets: 1 |
| T3D4214 | Diethylamine 71247-25-1 | C4H11N 73.137 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D4494 | Diazoxon 962-58-3 | C12H21N2O4P 288.280 g/mol |  |
| Diazoxon is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholinestera...more Number of Targets: 12 |
| T3D3241 | Diacetyl 431-03-8 | C4H6O2 86.089 g/mol |  |
| Diacetyl is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholinestera...more Number of Targets: 4 |
| T3D4430 | Deoxyuridine triphosphate 1173-82-6 | C9H15N2O14P3 468.142 g/mol |  |
| Deoxyuridine triphosphate (dUTP) can be misincorporated into DNA and cause DNA damage. The extent of DNA damage caused by dUTP is dependent on the levels of the pyroph...more Number of Targets: 3 |