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Displaying toxin 1 - 25 of 3678 in total
T3DB ID Name
CAS Number
Formula
Weight
StructureTypeMechanism of Toxicity
T3D4026(+)-Calycanthine
595-05-1
C22H26N4
346.469 g/mol
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  • Amine
  • Food Toxin
  • Metabolite
  • Natural Compound
  • Organic Compound
  • Plant Toxin
The principal alkaloid of the family Calycanthaceae, calycanthine has long been recognized as a central convulsant. Convulsant actions of calycanthine is mediated, at ...more
Number of Targets: 0
T3D4930(-)-alpha-Pinene
7785-26-4
C10H16
136.234 g/mol
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  • Food Toxin
  • Metabolite
  • Natural Compound
  • Organic Compound
  • Plant Toxin
Not Available
Number of Targets: 1
T3D3081(-)-Gossypol
90141-22-3
C30H30O8
518.554 g/mol
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  • Ester
  • Food Toxin
  • Metabolite
  • Natural Compound
  • Organic Compound
  • Plant Toxin
Gossypol may cause apoptosis via the regulation of Bax and Bcl-2 proteins. It is also an inhibitor of calcineurin and protein kinases C, and has been shown to bind cal...more
Number of Targets: 23
T3D1062(2E)-1-Methyl-2-(nitromethylidene)pyrrolidine
94662-64-3
C6H10N2O2
142.156 g/mol
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  • Amine
  • Nitromethylene
  • Organic Compound
  • Pesticide
  • Synthetic Compound
Acts as a neurotransmitter mimic , having both excitatory and depressant effects, eventually blocking postsynaptic nicotinic receptors. (T10)
Number of Targets: 5
T3D1055(2E)-2-(Nitromethylidene)-1,3-thiazinane
58842-20-9
C5H8N2O2S
160.194 g/mol
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  • Amine
  • Ether
  • Nitromethylene
  • Organic Compound
  • Pesticide
  • Synthetic Compound
Acts as a neurotransmitter mimic , having both excitatory and depressant effects, eventually blocking postsynaptic nicotinic receptors. (T10)
Number of Targets: 5
T3D1059(2E)-2-(Nitromethylidene)-1-prop-2-enylpyrrolidine
40990-27-0
C8H12N2O2
168.193 g/mol
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  • Amine
  • Nitromethylene
  • Organic Compound
  • Pesticide
  • Synthetic Compound
Acts as a neurotransmitter mimic , having both excitatory and depressant effects, eventually blocking postsynaptic nicotinic receptors. (T10)
Number of Targets: 5
T3D1051(2E)-3-Benzyl-2-(nitromethylidene)-1,3-thiazolidine
94776-91-7
C11H12N2O2S
236.290 g/mol
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  • Amine
  • Aromatic Hydrocarbon
  • Ether
  • Nitromethylene
  • Organic Compound
  • Pesticide
  • Synthetic Compound
Acts as a neurotransmitter mimic , having both excitatory and depressant effects, eventually blocking postsynaptic nicotinic receptors. (T10)
Number of Targets: 5
T3D4843(2E,4E)-2,4-Hexadienoic acid
110-44-1
C6H8O2
112.127 g/mol
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  • Ester
  • Food Additive
  • Food Toxin
  • Household Toxin
  • Metabolite
  • Organic Compound
  • Preservative
  • Synthetic Compound
Not Available
Number of Targets: 1
T3D2452(2S,4R,5S)-Muscarine
300-54-9
C9H20NO2
174.260 g/mol
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  • Ether
  • Food Toxin
  • Fungal Toxin
  • Metabolite
  • Mycotoxin
  • Natural Compound
  • Organic Compound
Muscarine is a competitive inhibitor. It mimics the action of the neurotransmitter acetylcholine at acetylcholine receptors. (L1011)
Number of Targets: 8
T3D1060(2Z)-1-Benzyl-2-(nitromethylidene)pyrrolidine
57734-58-4
C12H14N2O2
218.252 g/mol
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  • Amine
  • Aromatic Hydrocarbon
  • Nitromethylene
  • Organic Compound
  • Pesticide
  • Synthetic Compound
Acts as a neurotransmitter mimic , having both excitatory and depressant effects, eventually blocking postsynaptic nicotinic receptors. (T10)
Number of Targets: 5
T3D1058(2Z)-1-Ethyl-2-(nitromethylidene)pyrrolidine
26171-04-0
C7H12N2O2
156.182 g/mol
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  • Amine
  • Nitromethylene
  • Organic Compound
  • Pesticide
  • Synthetic Compound
Acts as a neurotransmitter mimic , having both excitatory and depressant effects, eventually blocking postsynaptic nicotinic receptors. (T10)
Number of Targets: 5
T3D1047(2Z)-1-Methyl-2-(nitromethylidene)pyrrolidine
26171-05-1
C6H10N2O2
142.156 g/mol
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  • Amine
  • Nitromethylene
  • Organic Compound
  • Pesticide
  • Synthetic Compound
Acts as a neurotransmitter mimic , having both excitatory and depressant effects, eventually blocking postsynaptic nicotinic receptors. (T10)
Number of Targets: 5
T3D1066(3Z)-2-Ethyl-3-(nitromethylidene)-3a,4,5,6,7,7a-hexahydro-1H-isoindole
56593-86-3
C11H18N2O2
210.273 g/mol
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  • Amine
  • Cyanide Compound
  • Nitromethylene
  • Organic Compound
  • Pesticide
  • Synthetic Compound
Acts as a neurotransmitter mimic , having both excitatory and depressant effects, eventually blocking postsynaptic nicotinic receptors. (T10)
Number of Targets: 5
T3D1054(4E)-4-(Nitromethylidene)-1,2,3,5-tetrahydro-3-benzazepine
58350-08-6
C11H12N2O2
204.225 g/mol
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  • Amine
  • Aromatic Hydrocarbon
  • Nitromethylene
  • Organic Compound
  • Pesticide
  • Synthetic Compound
Acts as a neurotransmitter mimic , having both excitatory and depressant effects, eventually blocking postsynaptic nicotinic receptors. (T10)
Number of Targets: 5
T3D1260(Acetyloxy)triphenylstannane
900-95-8
C20H21O2Sn
412.090 g/mol
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  • Food Toxin
  • Metabolite
  • Organic Compound
  • Organometallic
  • Pesticide
  • Synthetic Compound
  • Tin Compound
Organotin compounds produce neurotoxic and immunotoxic effects. Organotins may directly activate glial cells contributing to neuronal cell degeneration by local releas...more
Number of Targets: 12
T3D1426(Benzene)chromium tricarbonyl
12082-08-5
C9H6CrO3
214.135 g/mol
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  • Aromatic Hydrocarbon
  • Chromium Compound
  • Industrial/Workplace Toxin
  • Organic Compound
  • Organometallic
  • Pollutant
  • Synthetic Compound
Trivalent chromium may also form complexes with peptides, proteins, and DNA, resulting in DNA-protein crosslinks, DNA strand breaks, DNA-DNA interstrand crosslinks, ch...more
Number of Targets: 5
T3D3888(E)-Monocrotophos
6923-22-4
C7H14NO5P
223.164 g/mol
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  • Amide
  • Amine
  • Ester
  • Food Toxin
  • Insecticide
  • Metabolite
  • Organic Compound
  • Organophosphate
  • Pesticide
  • Synthetic Compound
(E)-Monocrotophos is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcho...more
Number of Targets: 4
T3D4957(E)-N-[2-[[5-(Dimethylaminomethyl)furan-2-yl]methylsulfanyl]ethyl]-1-(4-methylpiperazin-1-yl)-2-nitroethenamine
102787-23-5
C17H29N5O3S
383.509 g/mol
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  • Pesticide
  • Synthetic Compound
Acts as a neurotransmitter mimic , having both excitatory and depressant effects, eventually blocking postsynaptic nicotinic receptors. (T10)
Number of Targets: 0
T3D2702(R)-lipoic acid
62-46-4
C8H14O2S2
206.326 g/mol
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  • Animal Toxin
  • Antioxidant
  • Dietary Supplement
  • Drug
  • Household Toxin
  • Metabolite
  • Micronutrient
  • Natural Compound
  • Nutraceutical
  • Organic Compound
  • Plant Toxin
  • Supplement
  • Vitamin B Complex
(R)-lipoic acid is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholi...more
Number of Targets: 6
T3D4028(S)-2-Propylpiperidine
458-88-8
C8H17N
127.227 g/mol
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  • Amine
  • Food Toxin
  • Metabolite
  • Natural Compound
  • Organic Compound
  • Plant Toxin
(S)-2-Propylpiperidine is a neurotoxin which disrupts the peripheral nervous system. It is toxic to humans and all classes of livestock; less than 0.2g is fatal to hum...more
Number of Targets: 0
T3D4027(S)-Isocorydine
475-67-2
C20H23NO4
341.401 g/mol
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  • Amine
  • Ether
  • Food Toxin
  • Metabolite
  • Natural Compound
  • Organic Compound
  • Plant Toxin
Isocorydine induces G2/M phase arrest by increasing cyclin B1 and p-CDK1 expression levels, which was caused by decreasing the expression and inhibiting the activation...more
Number of Targets: 1
T3D3665(S,E)-Zearalenone
17924-92-4
C18H22O5
318.364 g/mol
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  • Ester
  • Ether
  • Food Toxin
  • Fungal Toxin
  • Metabolite
  • Mycotoxin
  • Natural Compound
  • Organic Compound
Zearalenone's genotoxicity results from it's ability to cause DNA fragmentation, chromosome aberrations, and DNA adduct formation. It exerts cytotoxic effects by enhan...more
Number of Targets: 14
T3D4873(±)-2-(1-Methylpropyl)-4,6-dinitrophenol
88-85-7
C10H12N2O5
240.213 g/mol
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  • Acaricide
  • Food Toxin
  • Herbicide
  • Metabolite
  • Organic Compound
  • Pesticide
  • Synthetic Compound
Not Available
Number of Targets: 6
T3D1088(±)-Metalaxyl
57837-19-1
C15H21NO4
279.332 g/mol
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  • Amide
  • Amine
  • Aromatic Hydrocarbon
  • Chloroacetanilide
  • Ester
  • Ether
  • Food Toxin
  • Household Toxin
  • Metabolite
  • Organic Compound
  • Organochloride
  • Pesticide
  • Synthetic Compound
Binds to nAChRs in nervous systems. It also causes endocrine disruption in humans by binding to and inhibiting the estrogen receptor. (T10, A590)
Number of Targets: 17
T3D3878(±)-Methamidophos
115182-35-9
C2H8NO2PS
141.129 g/mol
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  • Amide
  • Food Toxin
  • Insecticide
  • Metabolite
  • Organic Compound
  • Organophosphate
  • Pesticide
  • Synthetic Compound
(±)-Methamidophos is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcho...more
Number of Targets: 2
Displaying toxin 1 - 25 of 3678 in total