Browsing Toxins
Displaying toxin 3001 - 3025 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D2010 | 3,3',4,4',5-Pentabromobiphenyl 84303-46-8 | C12H5Br5 548.688 g/mol |  |
| The exact mechanism of toxicty of PBBs varies depending on the specific congener. The predominant interaction is believed to involve the aryl hydrocarbon receptor (AhR...more Number of Targets: 1 |
| T3D0558 | 3,3',4,4',5,5'-Hexachlorobiphenyl 32774-16-6 | C12H4Cl6 360.878 g/mol |  |
| The mechanism of action varies with the specific PCB. Dioxin-like PCBs bind to the aryl hydrocarbon receptor, which disrupts cell function by altering the transcriptio...more Number of Targets: 7 |
| T3D1976 | 3,3',4,4',5,5'-Hexabromobiphenyl 60044-26-0 | C12H4Br6 627.584 g/mol |  |
| The exact mechanism of toxicty of PBBs varies depending on the specific congener. The predominant interaction is believed to involve the aryl hydrocarbon receptor (AhR...more Number of Targets: 1 |
| T3D4996 | 22,23-dihydroavermectin b1b 70209-81-3 | C47H72O14 861.066 g/mol |  |
| Ivermectin binds selectively and with high affinity to glutamate-gated chloride ion channels in invertebrate muscle and nerve cells of the microfilaria. This binding c...more Number of Targets: 14 |
| T3D4995 | 22,23-dihydroavermectin b1a 71827-03-7 | C48H74O14 875.093 g/mol |  |
| Ivermectin binds selectively and with high affinity to glutamate-gated chloride ion channels in invertebrate muscle and nerve cells of the microfilaria. This binding c...more Number of Targets: 14 |
| T3D1045 | 2-[(2E)-2-(Nitromethylidene)pyrrolidin-1-yl]acetonitrile 1164504-23-7 | C7H9N3O2 167.165 g/mol |  |
| Acts as a neurotransmitter mimic , having both excitatory and depressant effects, eventually blocking postsynaptic nicotinic receptors. (T10) Organic nitriles decompos...more Number of Targets: 5 |
| T3D1061 | 2-[(2E)-2-(Nitromethylene)hydrazino]naphthalene 302544-16-7 | C11H9N3O2 215.208 g/mol |  |
| Acts as a neurotransmitter mimic , having both excitatory and depressant effects, eventually blocking postsynaptic nicotinic receptors. (T10) Number of Targets: 5 |
| T3D3944 | 2-Tert-butylphenol 88-18-6 | C10H14O 150.218 g/mol |  |
| Not Available Number of Targets: 5 |
| T3D4859 | 2-tert-Butyl-1,4-benzenediol 1948-33-0 | C10H14O2 166.217 g/mol |  |
| Not Available Number of Targets: 7 |
| T3D3231 | 2-Propenyl 3-methylbutanoate 2835-39-4 | C8H14O2 142.196 g/mol |  |
| Allyl isovalerate has low irritancy potential. It is deduced that one of its metabolites,
isovaleric acid, is toxic, based upon the effects of an inborn error of leuci...more Number of Targets: 0 |
| T3D3900 | 2-Phenoxyethanol 122-99-6 | C8H10O2 138.164 g/mol |  |
| 2-Phenoxyethanol is a glycol ether. Glycol ethers can produce toxicity following oxidation to the corresponding aldehyde and alkoxyacetic acid by alcohol dehydrogenase...more Number of Targets: 2 |
| T3D4908 | 2-Pentyl-3-phenyl-2-propenal 122-40-7 | C14H18O 202.292 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D3459 | 2-Pentene 109-68-2 | C5H10 70.133 g/mol |  |
| Petroleum distillates are central nervous system depressants and cause pulmonary damage. (A600) Number of Targets: 0 |
| T3D0072 | 2-Oxohexane 591-78-6 | C6H12O 100.159 g/mol |  |
| 2-Hexanone's toxicity is believed to be caused by covalent binding of its metabolites, especially 2,5-hexanedione, with axonal components of nerve tissue and inhibitio...more Number of Targets: 16 |
| T3D4186 | 2-Octenal 2363-89-5 | C8H14O 126.196 g/mol |  |
| Uremic toxins such as 2-Octenal are actively transported into the kidneys via organic ion transporters (especially OAT3). Increased levels of uremic toxins can stimula...more Number of Targets: 3 |
| T3D4187 | 2-Nonenal 2463-53-8 | C9H16O 140.223 g/mol |  |
| Uremic toxins such as 2-Nonenall are actively transported into the kidneys via organic ion transporters (especially OAT3). Increased levels of uremic toxins can stimul...more Number of Targets: 3 |
| T3D3579 | 2-Nitrophenol 88-75-5 | C6H5NO3 139.109 g/mol |  |
| The nitrite in nitrophenols causes the autocatalytic oxidation of oxyhemoglobin to hydrogen peroxide and methemoglobin. This elevation of methemoglobin levels is a con...more Number of Targets: 10 |
| T3D1049 | 2-Nitromethylene-piperidine 50902-03-9 | C6H10N2O2 142.156 g/mol |  |
| Acts as a neurotransmitter mimic , having both excitatory and depressant effects, eventually blocking postsynaptic nicotinic receptors. (T10) Number of Targets: 5 |
| T3D1048 | 2-Nitromethylene-azepane 61018-99-3 | C7H12N2O2 156.182 g/mol |  |
| Acts as a neurotransmitter mimic , having both excitatory and depressant effects, eventually blocking postsynaptic nicotinic receptors. (T10) Number of Targets: 5 |
| T3D3970 | 2-Naphthol 135-19-3 | C10H8O 144.170 g/mol |  |
| Not Available Number of Targets: 5 |
| T3D1917 | 2-Monobromobiphenyl 252-07-7 | C12H9Br 233.104 g/mol |  |
| The exact mechanism of toxicty of PBBs varies depending on the specific congener. The predominant interaction is believed to involve the aryl hydrocarbon receptor (AhR...more Number of Targets: 1 |
| T3D2404 | 2-Methylpentane 107-83-5 | C6H14 86.175 g/mol |  |
| Hexane's toxicity is caused by it neurotoxic metabolite, 2,5-hexanedione. It damages the central and peripheral nervous system by causing axonal swelling and degenerat...more Number of Targets: 4 |
| T3D0158 | 2-Methylnaphthalene 91-57-6 | C11H10 142.197 g/mol |  |
| The ability of PAH's to bind to blood proteins such as albumin allows them to be transported throughout the body. Many PAH's induce the expression of cytochrome P450 e...more Number of Targets: 4 |
| T3D3432 | 2-Methylhexane 591-76-4 | C7H16 100.202 g/mol |  |
| Petroleum distillates are central nervous system depressants and cause pulmonary damage. (A600) Number of Targets: 0 |
| T3D3441 | 2-Methylheptane 592-27-8 | C8H18 114.229 g/mol |  |
| Petroleum distillates are central nervous system depressants and cause pulmonary damage. (A600) Number of Targets: 0 |