Browsing Toxins
Displaying toxin 3026 - 3050 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D0708 | Pyridinium dichromate 20039-37-6 | C10H12Cr2N2O7 376.204 g/mol |  |
| Hexavalent chromium's carcinogenic effects are caused by its metabolites, pentavalent and trivalent chromium. The DNA damage may be caused by hydroxyl radicals produce...more Number of Targets: 5 |
| T3D2820 | Pyridostigmine 155-97-5 | C9H13N2O2 181.211 g/mol |  |
| Pyridostigmine is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholin...more Number of Targets: 2 |
| T3D2701 | Pyridoxine 65-23-6 | C8H11NO3 169.178 g/mol |  |
| Vitamin B6 is the collective term for a group of three related compounds, pyridoxine (PN), pyridoxal (PL) and pyridoxamine (PM), and their phosphorylated derivatives, ...more Number of Targets: 6 |
| T3D4779 | Pyrimethamine 58-14-0 | C12H13ClN4 248.711 g/mol |  |
| Pyrimethamine inhibits the dihydrofolate reductase of plasmodia and thereby blocks the biosynthesis of purines and pyrimidines, which are essential for DNA synthesis a...more Number of Targets: 10 |
| T3D4532 | Pyrimethanil 53112-28-0 | C12H13N3 199.252 g/mol |  |
| Not Available Number of Targets: 11 |
| T3D3916 | Pyriproxyfen 95737-68-1 | C20H19NO3 321.370 g/mol |  |
| Not Available Number of Targets: 10 |
| T3D3917 | Pyrithiobac-sodium 123343-16-8 | C13H10ClN2NaO4S 348.737 g/mol |  |
| Not Available Number of Targets: 7 |
| T3D4575 | Pyrocatechol 120-80-9 | C6H6O2 110.111 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D4270 | Pyroglutamic acid 98-79-3 | C5H7NO3 129.114 g/mol |  |
| 5-Oxoprolinuria develops in moderate to severe cases of glutathione synthetase deficiency. The deficiency in glutathione synthetase leads to the accumulation of γ-glut...more Number of Targets: 12 |
| T3D1005 | Pyrolan 87-47-8 | C13H15N3O2 245.277 g/mol |  |
| Pyrolan is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carbamoylation of the active sites of...more Number of Targets: 2 |
| T3D4959 | Pyrophosphate 14000-31-8 | O7P2 173.946 g/mol |  |
| Not Available Number of Targets: 0 |
| T3D4325 | Pyruvic acid 127-17-3 | C3H4O3 88.062 g/mol |  |
| Pyruvate serves as a biological fuel by being converted to acetyl coenzyme A, which enters the tricarboxylic acid or Krebs cycle where it is metabolized to produce ATP...more Number of Targets: 16 |
| T3D3637 | Quaternium-10 80702-43-8 | C21H46ClN 348.050 g/mol |  |
| While quaternium-10 itself is not toxic, it is a nitrosating agent. Nitrosating agents may decompose and/or react to cause nitrosamine contamination. Nitrosamines are ...more Number of Targets: 1 |
| T3D3628 | Quaternium-15 4080-31-3 | C9H16Cl2N4 251.156 g/mol |  |
| Quaternium-15 is a formaldehyde releaser. It is likely that formaldehyde toxicity occurs when intracellular levels saturate formaldehyde dehydrogenase activity, allowi...more Number of Targets: 2 |
| T3D3633 | Quaternium-22 51812-80-7 | C13H29ClN2O7 360.832 g/mol |  |
| While quaternium-22 itself is not toxic, it is a nitrosating agent. Nitrosating agents may decompose and/or react to cause nitrosamine contamination. Nitrosamines are ...more Number of Targets: 1 |
| T3D3636 | Quaternium-52 58069-11-7 | C30H64NO10P 629.804 g/mol |  |
| While quaternium-52 itself is not toxic, it is a nitrosating agent. Nitrosating agents may decompose and/or react to cause nitrosamine contamination. Nitrosamines are ...more Number of Targets: 1 |
| T3D3055 | Quazepam 36735-22-5 | C17H11ClF4N2S 386.794 g/mol |  |
| Benzodiazepines bind nonspecifically to benzodiazepine receptors, which affects muscle relaxation, anticonvulsant activity, motor coordination, and memory. As benzodia...more Number of Targets: 18 |
| T3D4758 | Quercetin 117-39-5 | C15H10O7 302.236 g/mol |  |
| Quercetin is a specific quinone reductase 2 (QR2) inhibitor, an enzyme (along with the human QR1 homolog) which catalyzes metabolism of toxic quinolines. Inhibition of...more Number of Targets: 12 |
| T3D2555 | Quetiapine 111974-69-7 | C21H25N3O2S 383.507 g/mol |  |
| The mechanism of action of quetiapine, as with other drugs used to treat schizophrenia, is unknown. However, it is thought that the drug's therapeutic activity in schi...more Number of Targets: 30 |
| T3D4733 | Quinapril 85441-61-8 | C25H30N2O5 438.516 g/mol |  |
| There are two isoforms of ACE: the somatic isoform, which exists as a glycoprotein comprised of a single polypeptide chain of 1277; and the testicular isoform, which h...more Number of Targets: 1 |
| T3D3918 | Quinclorac 84087-01-4 | C10H5Cl2NO2 242.058 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D3063 | Quinestrol 152-43-2 | C25H32O2 364.520 g/mol |  |
| Estrogens diffuse into their target cells and interact with a protein receptor (the estrogen receptor). Estrogen interacts with a target cell receptor. When the estrog...more Number of Targets: 1 |
| T3D2800 | Quinine 130-95-0 | C20H24N2O2 324.417 g/mol |  |
| The theorized mechanism of action for quinine and related anti-malarial drugs is that these drugs are toxic to the malaria parasite. Specifically, the drugs interfere ...more Number of Targets: 3 |
| T3D5004 | Quinolacetic acid 55604-87-0 | C8H8O4 168.148 g/mol |  | Not Available | Not Available Number of Targets: 0 |
| T3D0634 | Quinoline 91-22-5 | C9H7N 129.159 g/mol |  |
| The ability of PAH's to bind to blood proteins such as albumin allows them to be transported throughout the body. Many PAH's induce the expression of cytochrome P450 e...more Number of Targets: 6 |