Browsing Toxins
Displaying toxin 3401 - 3425 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D2016 | 2,2',3,5',6-Pentabromobiphenyl 88700-05-4 | C12H5Br5 548.688 g/mol |  |
| The exact mechanism of toxicty of PBBs varies depending on the specific congener. The predominant interaction is believed to involve the aryl hydrocarbon receptor (AhR...more Number of Targets: 1 |
| T3D2021 | 2,3,4,4',5-Pentabromobiphenyl 96551-70-1 | C12H5Br5 548.688 g/mol |  |
| The exact mechanism of toxicty of PBBs varies depending on the specific congener. The predominant interaction is believed to involve the aryl hydrocarbon receptor (AhR...more Number of Targets: 1 |
| T3D2024 | 2,2',4,4',6-Pentabromobiphenyl 97038-97-6 | C12H5Br5 548.688 g/mol |  |
| The exact mechanism of toxicty of PBBs varies depending on the specific congener. The predominant interaction is believed to involve the aryl hydrocarbon receptor (AhR...more Number of Targets: 1 |
| T3D2027 | 2,2',4,6,6'-Pentabromobiphenyl 97063-75-7 | C12H5Br5 548.688 g/mol |  |
| The exact mechanism of toxicty of PBBs varies depending on the specific congener. The predominant interaction is believed to involve the aryl hydrocarbon receptor (AhR...more Number of Targets: 1 |
| T3D2032 | 2,2',3,3',4-Pentabromobiphenyl Not Available | C12H5Br5 548.688 g/mol |  |
| The exact mechanism of toxicty of PBBs varies depending on the specific congener. The predominant interaction is believed to involve the aryl hydrocarbon receptor (AhR...more Number of Targets: 0 |
| T3D4067 | Convallatoxin 508-75-8 | C29H42O10 550.638 g/mol |  |
| Convallatoxin (CNT) is classified as a cardiac glycoside. Cardiac glycosides are well known Na+/K+-ATPase inhibitors, and some of them are used to treat congestive hea...more Number of Targets: 0 |
| T3D1499 | Potassium aluminium fluoride 14484-69-6 | Al5F20K 553.974 g/mol |  |
| The main target organs of aluminum are the central nervous system and bone. Aluminum binds with dietary phosphorus and impairs gastrointestinal absorption of phosphoru...more Number of Targets: 3 |
| T3D2568 | Ceftriaxone 73384-59-5 | C18H18N8O7S3 554.580 g/mol |  |
| Ceftriaxone works by inhibiting the mucopeptide synthesis in the bacterial cell wall. The beta-lactam moiety of Ceftriaxone binds to carboxypeptidases, endopeptidases,...more Number of Targets: 4 |
| T3D1392 | Cobalt(II) citrate 866-81-9 | C12H10Co3O14 554.999 g/mol |  |
| Cobalt is believed to exhibit its toxicity through a oxidant-based and free radical-based processes. It produces oxygen radicals and may be oxidized to ionic cobalt, c...more Number of Targets: 35 |
| T3D1281 | Dimethyltin bis(isooctyl mercaptoacetate) 26636-01-1 | C22H44O4S2Sn 555.420 g/mol |  |
| Organotin compounds produce neurotoxic and immunotoxic effects. Organotins may directly activate glial cells contributing to neuronal cell degeneration by local releas...more Number of Targets: 12 |
| T3D1899 | Tris(3-(trifluoromethyl)phenyl)antimony 386-91-4 | C21H12F9Sb 557.070 g/mol |  |
| The inhalation data suggests that the myocardium is a target of antimony toxicity. It is possible that antimony affects circulating glucose by interfering with enzymes...more Number of Targets: 20 |
| T3D4980 | Atorvastatin 134523-00-5 | C33H34FN2O5 557.632 g/mol |  |
| Atorvastatin selectively and competitively inhibits the hepatic enzyme HMG-CoA reductase. As HMG-CoA reductase is responsible for converting HMG-CoA to mevalonate in t...more Number of Targets: 3 |
| T3D1841 | Selenium dimethyldithiocarbamate 144-34-3 | C12H24N4S8Se 559.830 g/mol |  |
| Selenium readily substitutes for sulfur in biomolecules and in many biochemical reactions, especially when the concentration of selenium is high and the concentration ...more Number of Targets: 0 |
| T3D0352 | Mercury(I) bromide 15385-58-7 | Br2Hg2 560.990 g/mol |  |
| High-affinity binding of the divalent mercuric ion to thiol or sulfhydryl groups of proteins is believed to be the major mechanism for the activity of mercury. Through...more Number of Targets: 56 |
| T3D3689 | Ergocornine 564-36-3 | C31H39N5O5 561.672 g/mol |  |
| Ergoline alkaloids tend to act as a group, producing complex and variable effects of partial agonism or antagonism at adrenergic, dopaminergic, and serotonergic recept...more Number of Targets: 0 |
| T3D1357 | Mercaptomerin 20223-84-1 | C16H27HgNO6S 562.040 g/mol |  |
| High-affinity binding of the divalent mercuric ion to thiol or sulfhydryl groups of proteins is believed to be the major mechanism for the activity of mercury. Through...more Number of Targets: 50 |
| T3D4440 | Protoporphyrin IX 553-12-8 | C34H34N4O4 562.658 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D2164 | 1,2,3,7,8-Pentabromodibenzofuran 107555-93-1 | C12H3Br5O 562.672 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2230 | 2,3,4,6,7-Pentabromodibenzofuran 124388-77-8 | C12H3Br5O 562.672 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2234 | 2,3,4,7,8-Pentabromodibenzofuran 131166-92-2 | C12H3Br5O 562.672 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D4005 | Perfluoroundecanoic acid 2058-94-8 | C11HF21O2 564.091 g/mol |  |
| Not Available Number of Targets: 9 |
| T3D2040 | Pentabromodiphenyl ethers 32534-81-9 | C12H5Br5O 564.688 g/mol |  |
| Like other halogenated aromatic hydrocarbons, polybrominated diphenyl ethers bind to the cellular aryl hydrocarbon receptor (AhR), which regulates the synthesis of a v...more Number of Targets: 7 |
| T3D4439 | Protoporphyrinogen IX 7412-77-3 | C34H40N4O4 568.706 g/mol |  |
| Not Available Number of Targets: 0 |
| T3D3763 | Janthitrem C 73561-91-8 | C37H47NO4 569.773 g/mol |  |
| Tremorgenic mycotoxins exert their toxic effects by interfering with neurotransmitter release, possibly by causing degeneration of nerve terminals. They are thought to...more Number of Targets: 22 |
| T3D4798 | Iopanoic acid 96-83-3 | C11H12I3NO2 570.932 g/mol |  |
| Not Available Number of Targets: 1 |