Tmic
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Displaying toxins 201 - 225 of 3678 in total
T3DB ID Name
CAS Number
Formula
Weight
StructureTypeMechanism of Toxicity
T3D02482,4-Dichlorophenoxyacetic acid
94-75-7
C8H6Cl2O3
221.037 g/mol
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  • Aromatic Hydrocarbon
  • Ether
  • Household Toxin
  • Industrial/Workplace Toxin
  • Metabolite
  • Organic Compound
  • Organochloride
  • Pesticide
  • Pollutant
  • Synthetic Compound
2,4-Dichlorophenoxyacetic acid is a strong oxidant and is known to cause lipid peroxidation and the generation of free radicals that can modify lipids and proteins. It...more
Number of Targets: 9
T3D0249Dibromochloromethane
124-48-1
CHBr2Cl
208.280 g/mol
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  • Bromide Compound
  • Food Toxin
  • Indicator and Reagent
  • Industrial/Workplace Toxin
  • Metabolite
  • Organic Compound
  • Organobromide
  • Organochloride
  • Pollutant
  • Synthetic Compound
Dibromochloromethane is oxidized into trihalomethanol by the cytochrome P-450 mixed function oxidase system of liver. Trihalomethanol then decomposes by loss of hydrog...more
Number of Targets: 2
T3D0252N,N-Dimethylformamide
1968-12-02
C3H7NO
73.094 g/mol
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  • Amide
  • Amine
  • Food Toxin
  • Industrial/Workplace Toxin
  • Metabolite
  • Organic Compound
  • Pollutant
  • Solvent
  • Synthetic Compound
While the mechanism of action of dimethyl formamide has not bee fully elucidated, thiocarbamate pesticides have been shown to inhibit aldehyde dehydrogenases. (A2459)
Number of Targets: 4
T3D0253Pyrene
129-00-0
C16H10
202.251 g/mol
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  • Aromatic Hydrocarbon
  • Food Toxin
  • Industrial By-product/Pollutant
  • Industrial/Workplace Toxin
  • Metabolite
  • Natural Compound
  • Organic Compound
  • Pollutant
  • Polycyclic Aromatic Hydrocarbon
The ability of PAH's to bind to blood proteins such as albumin allows them to be transported throughout the body. Many PAH's induce the expression of cytochrome P450 e...more
Number of Targets: 8
T3D0255Ethyl ether
60-29-7
C4H10O
74.122 g/mol
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  • Ether
  • Household Toxin
  • Industrial/Workplace Toxin
  • Lachrymator
  • Organic Compound
  • Solvent
  • Synthetic Compound
Diethyl ether inhibits alcohol dehydrogenase. This slows down the metabolism of ethanol and also inhibits the metabolism of other drugs requiring oxidative metabolism....more
Number of Targets: 8
T3D02574-Nitrophenol
100-02-7
C6H5NO3
139.109 g/mol
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  • Aromatic Hydrocarbon
  • Food Toxin
  • Industrial Precursor/Intermediate
  • Industrial/Workplace Toxin
  • Metabolite
  • Nitrite
  • Organic Compound
  • Pesticide
  • Pollutant
  • Synthetic Compound
The nitrite in nitrophenols causes the autocatalytic oxidation of oxyhemoglobin to hydrogen peroxide and methemoglobin. This elevation of methemoglobin levels is a con...more
Number of Targets: 12
T3D0259Phosphine
7803-51-2
H3P
33.998 g/mol
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  • Food Toxin
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Metabolite
  • Non-Metal
  • Pesticide
  • Pollutant
  • Synthetic Compound
Phosphine inhibits cytochrome c oxidase, preventing mitochondrial oxidative phosphorylation. This non-competitive inhibition prevents cellular respiration and leads to...more
Number of Targets: 20
T3D02612,6-Dinitrotoluene
606-20-2
C7H6N2O4
182.134 g/mol
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  • Aromatic Hydrocarbon
  • Explosive Agent
  • Industrial/Workplace Toxin
  • Nitrite
  • Organic Compound
  • Plasticizer
  • Pollutant
  • Synthetic Compound
Dinitrotoluene may cause conversion of oxyhemoglobin to methemoglobin via oxidation of iron(II) to iron(III) by its metabolites. High levels of methemoglobin are remov...more
Number of Targets: 12
T3D0264Methyl parathion
298-00-0
C8H10NO5PS
263.207 g/mol
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  • Aromatic Hydrocarbon
  • Ester
  • Organic Compound
  • Organophosphate
  • Pesticide
  • Synthetic Compound
Methyl parathion is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylchol...more
Number of Targets: 14
T3D0265Pentaerythritol tetranitrate
1978-11-05
C5H8N4O12
316.137 g/mol
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  • Explosive Agent
  • Household Toxin
  • Industrial/Workplace Toxin
  • Nitrate
  • Organic Compound
  • Synthetic Compound
Nitrate's toxicity is a result of it's conversion to nitrite once in the body. Nitrite causes the autocatalytic oxidation of oxyhemoglobin to hydrogen peroxide and met...more
Number of Targets: 10
T3D0271Styrene
100-42-5
C8H8
104.149 g/mol
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  • Aromatic Hydrocarbon
  • Cigarette Toxin
  • Food Toxin
  • Household Toxin
  • Industrial Precursor/Intermediate
  • Industrial/Workplace Toxin
  • Metabolite
  • Natural Compound
  • Organic Compound
  • Pollutant
Styrene 7,8-oxide, a metabolite of styrene, can form DNA adducts by binding to deoxyguanosine. It is also mutagenic and causes increased frequency of sister chromatid ...more
Number of Targets: 1
T3D0275Adamsite
578-94-9
C12H9AsClN
277.581 g/mol
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  • Amine
  • Arsenic Compound
  • Industrial/Workplace Toxin
  • Organic Compound
  • Synthetic Compound
Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by co...more
Number of Targets: 45
T3D0276Arsenic trisulfide
1303-33-9
As4S6
492.076 g/mol
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  • Arsenic Compound
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Pollutant
  • Synthetic Compound
Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by co...more
Number of Targets: 44
T3D0277Arsenic disulfide
1303-32-8
AsHS
107.995 g/mol
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  • Arsenic Compound
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Pollutant
  • Synthetic Compound
Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by co...more
Number of Targets: 44
T3D0278Arsenic pentasulfide
1303-34-0
As2H10S5
320.248 g/mol
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  • Arsenic Compound
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Pollutant
  • Synthetic Compound
Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by co...more
Number of Targets: 44
T3D0279Arsenic trichloride
7784-34-1
AsCl3
181.281 g/mol
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  • Arsenic Compound
  • Inorganic Compound
  • Pesticide
  • Pollutant
  • Synthetic Compound
Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by co...more
Number of Targets: 44
T3D0282Arsenous acid
13464-58-9
AsH3O3
125.944 g/mol
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  • Arsenic Compound
  • Food Toxin
  • Inorganic Compound
  • Metalloid
  • Pesticide
  • Pollutant
  • Synthetic Compound
Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by co...more
Number of Targets: 44
T3D0285Ammonium arsenate
7784-44-3
AsH9N2O4
176.004 g/mol
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  • Arsenic Compound
  • Inorganic Compound
  • Pesticide
  • Pollutant
  • Synthetic Compound
Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by co...more
Number of Targets: 44
T3D0286Copper(II) arsenite
10290-12-7
AsCuHO3
187.474 g/mol
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  • Arsenic Compound
  • Copper Compound
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Metalloid
  • Pesticide
  • Pollutant
  • Synthetic Compound
Excess copper is sequestered within hepatocyte lysosomes, where it is complexed with metallothionein. Copper hepatotoxicity is believed to occur when the lysosomes bec...more
Number of Targets: 49
T3D0287Gallium arsenide
1303-00-0
AsGa
144.645 g/mol
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  • Arsenic Compound
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Pollutant
  • Synthetic Compound
Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by co...more
Number of Targets: 44
T3D0288Copper arsenate
10103-61-4
As2Cu3O8
468.476 g/mol
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  • Arsenic Compound
  • Copper Compound
  • Inorganic Compound
  • Metalloid
  • Pesticide
  • Pollutant
  • Synthetic Compound
Excess copper is sequestered within hepatocyte lysosomes, where it is complexed with metallothionein. Copper hepatotoxicity is believed to occur when the lysosomes bec...more
Number of Targets: 49
T3D0289Copper arsenate hydroxide
16102-92-4
AsCu2HO5
283.019 g/mol
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  • Arsenic Compound
  • Copper Compound
  • Inorganic Compound
  • Natural Compound
  • Pesticide
  • Pollutant
Excess copper is sequestered within hepatocyte lysosomes, where it is complexed with metallothionein. Copper hepatotoxicity is believed to occur when the lysosomes bec...more
Number of Targets: 49
T3D0290Potassium arsenite
10124-50-2
AsKO3
162.018 g/mol
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  • Arsenic Compound
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Metalloid
  • Pollutant
  • Synthetic Compound
Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by co...more
Number of Targets: 44
T3D0292Arsenic pentoxide
1303-28-2
As2O5
229.840 g/mol
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  • Arsenic Compound
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Metalloid
  • Pesticide
  • Pollutant
  • Synthetic Compound
Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by co...more
Number of Targets: 44
T3D0293Magnesium arsenate
10103-50-1
As2Mg3O8
350.753 g/mol
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  • Arsenic Compound
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Pollutant
  • Synthetic Compound
Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by co...more
Number of Targets: 45
Displaying toxins 201 - 225 of 3678 in total