Browsing Toxins By Category
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D2531 | Allopumiliotoxin 73376-38-2 | C16H29NO2 267.407 g/mol |  |
| Allopumiliotoxins may affect sodium and potassium channels in cells and inhibit calcium-dependent ATPase. (L1077, A313, A315) Number of Targets: 11 |
| T3D4936 | Allantoin 97-59-6 | C4H6N4O3 158.115 g/mol |  |
| Not Available Number of Targets: 2 |
| T3D2506 | Agitoxin 155646-21-2 | Not Available 4020.835 g/mol |  |
| Agitoxin binds to and blocks the Shaker potassium channel in Drosophila as well as to its mammalian homologue. (A157) Number of Targets: 8 |
| T3D4276 | Adenosine triphosphate 56-65-5 | C10H16N5O13P3 507.181 g/mol |  |
| ATP is able to store and transport chemical energy within cells. ATP also plays an important role in the synthesis of nucleic acids. ATP can be produced by various cel...more Number of Targets: 42 |
| T3D4275 | Adenosine 58-61-7 | C10H13N5O4 267.241 g/mol |  |
| Adenosine slows conduction time through the AV node and can interrupt the reentry pathways through the AV node, resulting in the restoration of normal sinus rhythm in ...more Number of Targets: 11 |
| T3D4279 | Adenine 73-24-5 | C5H5N5 135.127 g/mol |  |
| Adenine forms adenosine, a nucleoside, when attached to ribose, and deoxyadenosine when attached to deoxyribose, and it forms adenosine triphosphate (ATP), a nucleotid...more Number of Targets: 10 |
| T3D2633 | Acanthophin 126601-49-8 | Not Available 8386.795 g/mol |  |
| Acanthophin produces peripheral paralysis by blocking neuromuscular transmission at the postsynaptic site. It does this by binding to certain muscular and neuronal nic...more Number of Targets: 8 |
| T3D4991 | 9-Hydroxyphenanthrene 484-17-3 | C14H10O 194.229 g/mol |  |
| 9-phenanthrol is a recently identified inhibitor of the transient receptor potential melastatin (TRPM) 4 channel, a Ca(2+) -activated non-selective cation channel whos...more Number of Targets: 0 |
| T3D2465 | 54-Deoxyciguatoxin 139341-09-6 | C60H86O18 1095.314 g/mol |  |
| Ciguatoxin lowers the threshold for opening voltage-gated sodium channels in synapses of the nervous system. The effect of opening a sodium channel will cause depolari...more Number of Targets: 14 |
| T3D4298 | 5-Hydroxy-L-tryptophan 4350-09-8 | C11H12N2O3 220.225 g/mol |  |
| 5-Hydroxy-L-tryptophan is the immediate precursor of the neurotransmitter serotonin. An accumulation of 5-hydroxy-L-tryptophan in cerebrospinal fluid occurs in aromati...more Number of Targets: 1 |
| T3D4273 | 5-Aminolevulinic acid 106-60-5 | C5H9NO3 131.130 g/mol |  |
| According to the presumed mechanism of action, photosensitization following application of aminolevulinic acid (ALA) topical solution occurs through the metabolic conv...more Number of Targets: 3 |
| T3D4413 | 4-Hydroxyproline 51-35-4 | C5H9NO3 131.130 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D4269 | 4-Hydroxybutyric acid 591-81-1 | C4H8O3 104.105 g/mol |  |
| GHB reaches much higher concentrations in the brain and activates GABAB receptors, which are primarily responsible for its sedative effects. GHB receptors are densely ...more Number of Targets: 2 |
| T3D0905 | 3-Oxo-carbofuran 16709-30-1 | C12H13NO4 235.236 g/mol |  |
| 3-Oxo-carbofuran is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carbamoylation of the active...more Number of Targets: 2 |
| T3D4265 | 3-Methylglutaconic acid 5746-90-7 | C6H8O4 144.125 g/mol |  |
| Accumulation of 3-methylglutaconic acid in the body has been shown to be toxic. 3-methylglutaconyl-CoA hydratase is involved in the metabolism process of 3-methylgluta...more Number of Targets: 0 |
| T3D4424 | 3-Methyl-2-oxovaleric acid 1460-34-0 | C6H10O3 130.142 g/mol |  |
| 3-Methyl-2-oxovaleric acid is produced from isoleucine by cytosolic branched chain aminotransferase 1, whereupon it is further degraded by branched chain keto acid deh...more Number of Targets: 0 |
| T3D4262 | 3-Hydroxymethylglutaric acid 503-49-1 | C6H10O5 162.141 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D4263 | 3-Hydroxyisovaleric acid 625-08-1 | C5H10O3 118.131 g/mol |  |
| 3-Hydroxyisovaleric acid is a normal human metabolite excreted in the urine. Elevated levels of this compound are found in several disorders due to impairment of renal...more Number of Targets: 0 |
| T3D4357 | 3-Hydroxyglutaric acid 638-18-6 | C5H8O5 148.114 g/mol |  |
| Not Available Number of Targets: 2 |
| T3D0903 | 3-Hydroxy-carbofuran 16655-82-6 | C12H15NO4 237.252 g/mol |  |
| 3-Hydroxy-carbofuran is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carbamoylation of the ac...more Number of Targets: 2 |
| T3D4966 | 3-(3-Hydroxyphenyl)-3-hydroxypropanoic acid 3247-75-4 | C9H10O4 182.173 g/mol |  |
| Not Available Number of Targets: 0 |
| T3D4993 | 2-hydroxyflutamide 52806-53-8 | C11H11F3N2O4 292.211 g/mol |  |
| Hydroxyflutamide is an antiandrogen. Antiandrogens alter the androgen pathway by blocking the appropriate receptors, competing for binding sites on the cell's surface,...more Number of Targets: 0 |
| T3D4258 | 2-Hydroxyadipic acid 18294-85-4 | C6H10O5 162.141 g/mol |  |
| 2-Hydroxyadipic acid is a hydroxy-dicarboxylic acid formed by the reduction of 2-ketoadipic acid. Deficiency of 2-ketoadipic dehydrogenase causes 2-ketoadipic acidemia...more Number of Targets: 0 |
| T3D4868 | 2,6-Diethylaniline 579-66-8 | C10H15N 149.233 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D4804 | 2,4,6-Tribromophenol 118-79-6 | C6H3Br3O 330.799 g/mol |  |
| Not Available Number of Targets: 3 |