Browsing Toxins By Category
T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
---|---|---|---|---|---|
T3D2702 | (R)-lipoic acid 62-46-4 | C8H14O2S2 206.326 g/mol |
| (R)-lipoic acid is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholi...more Number of Targets: 6 | |
T3D3971 | 1-Hydroxypyrene 5315-79-7 | C16H12O 220.266 g/mol |
| Not Available Number of Targets: 15 | |
T3D3968 | 1-Naphthol 90-15-3 | C10H8O 144.170 g/mol |
| 1-Naphthol is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholineste...more Number of Targets: 5 | |
T3D4965 | 1-Pyrroline-5-carboxylic acid 2906-39-0 | C5H7NO2 113.115 g/mol |
| Not Available Number of Targets: 0 | |
T3D4282 | 17-Hydroxyprogesterone 68-96-2 | C21H30O3 330.461 g/mol |
| Not Available Number of Targets: 8 | |
T3D4832 | 17a-Estradiol 57-91-0 | C18H24O2 272.382 g/mol |
| Not Available Number of Targets: 9 | |
T3D4284 | 18-Hydroxycorticosterone 561-65-9 | C21H30O5 362.460 g/mol |
| 18-Hydroxycorticosterone is a derivative of corticosterone. It serves as an intermediate in the synthesis of aldosterone by the enzyme aldosterone synthase in the zona...more Number of Targets: 1 | |
T3D4990 | 2,2,4-Trimethyl-1,3-pentadienol diisobutyrate 6846-50-0 | C16H30O4 286.407 g/mol |
| Not Available Number of Targets: 0 | |
T3D4804 | 2,4,6-Tribromophenol 118-79-6 | C6H3Br3O 330.799 g/mol |
| Not Available Number of Targets: 3 | |
T3D4868 | 2,6-Diethylaniline 579-66-8 | C10H15N 149.233 g/mol |
| Not Available Number of Targets: 1 | |
T3D4258 | 2-Hydroxyadipic acid 18294-85-4 | C6H10O5 162.141 g/mol |
| 2-Hydroxyadipic acid is a hydroxy-dicarboxylic acid formed by the reduction of 2-ketoadipic acid. Deficiency of 2-ketoadipic dehydrogenase causes 2-ketoadipic acidemia...more Number of Targets: 0 | |
T3D4993 | 2-hydroxyflutamide 52806-53-8 | C11H11F3N2O4 292.211 g/mol |
| Hydroxyflutamide is an antiandrogen. Antiandrogens alter the androgen pathway by blocking the appropriate receptors, competing for binding sites on the cell's surface,...more Number of Targets: 0 | |
T3D4966 | 3-(3-Hydroxyphenyl)-3-hydroxypropanoic acid 3247-75-4 | C9H10O4 182.173 g/mol |
| Not Available Number of Targets: 0 | |
T3D0903 | 3-Hydroxy-carbofuran 16655-82-6 | C12H15NO4 237.252 g/mol |
| 3-Hydroxy-carbofuran is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carbamoylation of the ac...more Number of Targets: 2 | |
T3D4357 | 3-Hydroxyglutaric acid 638-18-6 | C5H8O5 148.114 g/mol |
| Not Available Number of Targets: 2 | |
T3D4263 | 3-Hydroxyisovaleric acid 625-08-1 | C5H10O3 118.131 g/mol |
| 3-Hydroxyisovaleric acid is a normal human metabolite excreted in the urine. Elevated levels of this compound are found in several disorders due to impairment of renal...more Number of Targets: 0 | |
T3D4262 | 3-Hydroxymethylglutaric acid 503-49-1 | C6H10O5 162.141 g/mol |
| Not Available Number of Targets: 1 | |
T3D4424 | 3-Methyl-2-oxovaleric acid 1460-34-0 | C6H10O3 130.142 g/mol |
| 3-Methyl-2-oxovaleric acid is produced from isoleucine by cytosolic branched chain aminotransferase 1, whereupon it is further degraded by branched chain keto acid deh...more Number of Targets: 0 | |
T3D4265 | 3-Methylglutaconic acid 5746-90-7 | C6H8O4 144.125 g/mol |
| Accumulation of 3-methylglutaconic acid in the body has been shown to be toxic. 3-methylglutaconyl-CoA hydratase is involved in the metabolism process of 3-methylgluta...more Number of Targets: 0 | |
T3D0905 | 3-Oxo-carbofuran 16709-30-1 | C12H13NO4 235.236 g/mol |
| 3-Oxo-carbofuran is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carbamoylation of the active...more Number of Targets: 2 | |
T3D4269 | 4-Hydroxybutyric acid 591-81-1 | C4H8O3 104.105 g/mol |
| GHB reaches much higher concentrations in the brain and activates GABAB receptors, which are primarily responsible for its sedative effects. GHB receptors are densely ...more Number of Targets: 2 | |
T3D4413 | 4-Hydroxyproline 51-35-4 | C5H9NO3 131.130 g/mol |
| Not Available Number of Targets: 1 | |
T3D4273 | 5-Aminolevulinic acid 106-60-5 | C5H9NO3 131.130 g/mol |
| According to the presumed mechanism of action, photosensitization following application of aminolevulinic acid (ALA) topical solution occurs through the metabolic conv...more Number of Targets: 3 | |
T3D4298 | 5-Hydroxy-L-tryptophan 4350-09-8 | C11H12N2O3 220.225 g/mol |
| 5-Hydroxy-L-tryptophan is the immediate precursor of the neurotransmitter serotonin. An accumulation of 5-hydroxy-L-tryptophan in cerebrospinal fluid occurs in aromati...more Number of Targets: 1 | |
T3D2465 | 54-Deoxyciguatoxin 139341-09-6 | C60H86O18 1095.314 g/mol |
| Ciguatoxin lowers the threshold for opening voltage-gated sodium channels in synapses of the nervous system. The effect of opening a sodium channel will cause depolari...more Number of Targets: 14 |