Browsing Toxins By Category
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D2627 | mu-Agatoxin 120500-28-9 | Not Available 4272.715 g/mol |  |
| mu-Agatoxins modify presynaptic voltage-activated sodium channels in the neuromuscular joints of insects. Modifying sodium channels leads to an increased sensitivity o...more Number of Targets: 0 |
| T3D2628 | kappa-Atracotoxin (Hadronyche versuta) Not Available | Not Available 3685.155 g/mol |  |
| kappa-Atracotoxins inhibit insect voltage-gated potassium channels. (T170, L1812) Number of Targets: 0 |
| T3D2629 | Hanatoxin 170780-01-5 | Not Available 4120.690 g/mol |  |
| Hanatoxin inhibits voltage-gated potassium channels by altering the gating energetics, which it does by occupying multiple binding sites on the channel. It can also in...more Number of Targets: 3 |
| T3D2630 | Sphingomyelinase D (Loxosceles intermedia) 9031-54-3 | Not Available 34158.125 g/mol |  |
| Sphingomyelinase D catalyzes the hydrolysis of sphingomyelin, inducing complement-dependent haemolysis, dermonecrosis, blood vessel permeability and platelet aggregati...more Number of Targets: 0 |
| T3D2631 | Heteroscodratoxin Not Available | Not Available 4003.400 g/mol |  |
| Heteroscodratoxin inhibits voltage-gated potassium channels by binding to the extracellular linker of the channel and shifting activation of the channel to more depola...more Number of Targets: 5 |
| T3D2671 | Rituximab 174722-31-7 | Not Available 36105.695 g/mol |  |
| Binds to the CD20 antigen which is found on mature B lymphocytes. The Fc domain recruits immune effector functions to mediate B-cell lysis. The antibody appears to ind...more Number of Targets: 12 |
| T3D3514 | Infliximab 170277-31-3 | Not Available 36105.695 g/mol |  |
| Infliximab neutralizes the biological activity of TNFa by binding with high affinity to the soluble and transmembrane forms of TNFa and inhibits binding of TNFa with i...more Number of Targets: 3 |
| T3D4726 | Alteplase 105857-23-6 | Not Available 62916.495 g/mol |  |
| Alteplase binds to fibrin rich clots via the fibronectin finger-like domain and the Kringle 2 domain. The protease domain then cleaves the Arg/Val bond in plasminogen ...more Number of Targets: 4 |