Browsing Toxins By Category
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D2510 | alpha-Cobratoxin 769933-79-1 | Not Available 7830.960 g/mol |  |
| alpha-Cobratoxin is a muscle-type nicotinic acetylcholine receptor (nAChR) antagonist. It causes paralysis by preventing the binding of acetylcholine to the nAChR, as ...more Number of Targets: 6 |
| T3D2539 | Calciseptine 134710-25-1 | Not Available 7044.155 g/mol |  |
| Calciseptine is a specific blocker of the L-type calcium channel, and as a result also a smooth muscle relaxant and an inhibitor of cardiac contractions. (T170) Number of Targets: 8 |
| T3D2540 | Calcicludine 178037-96-2 | Not Available 6986.205 g/mol |  |
| Calcicludine inhibits high-voltage-activated calcium channels, especially of the L-type. (L1092) Number of Targets: 10 |
| T3D2541 | Cardiotoxin (Naja atra) 155808-00-7 | Not Available 8991.970 g/mol |  |
| Cardiotoxin binds to the cell membrane and depolarizes cardiomyocytes. It also shows lytic activities on many other cells, including red blood cells. It also targets t...more Number of Targets: 11 |
| T3D2542 | Crotamine 58740-15-1 | Not Available 7518.980 g/mol |  |
| Crotamine specifically modifies voltage-sensitive sodium channels, it exhibits analgesic activity and causes severe muscle necrosis by a non-enzymatic mechanism. It al...more Number of Targets: 14 |
| T3D2543 | Crotoxin 9007-40-3 | Not Available 15272.965 g/mol |  |
| Crotoxin inhibits neuromuscular transmission by presynaptically blocking acetylcholine release from the nerve termini. (T170) Number of Targets: 0 |
| T3D2544 | Convulxin 37206-04-5 | Not Available 18140.725 g/mol |  |
| Convulxin binds to the platelet and collagen receptor, glycoprotein VI (GPVI). This causes platelet activation in the blood forming clots and a build up of pressure, w...more Number of Targets: 1 |
| T3D2545 | Dendrotoxin (Dendroaspis polylepis polylepis) 119128-61-9 | Not Available 7155.305 g/mol |  |
| Dendrotoxins block particular subtypes of voltage-gated potassium channels in neurons, thereby prolonging the duration of action potentials and enhancing the release o...more Number of Targets: 23 |
| T3D2546 | Dendrotoxin (Dendroaspis angusticeps) 74504-53-3 | Not Available 3417.825 g/mol |  |
| Dendrotoxins block particular subtypes of voltage-gated potassium channels in neurons, thereby prolonging the duration of action potentials and enhancing the release o...more Number of Targets: 23 |
| T3D2547 | Taicatoxin 112154-17-3 | Not Available 9711.255 g/mol |  |
| Taicatoxin blocks the voltage-dependent L-type calcium channels from the heart and on the small conductance calcium-activated potassium channels in the brain. (L1105) Number of Targets: 11 |
| T3D2549 | Eledoisin (Eledone cirrhosa) 69-25-0 | Not Available 1206.410 g/mol |  |
| Eledoisin is a tachykinin peptide. Tachykinins excite neurons, evoke behavioural responses, are potent vasodilators and secretagogues, and contract (directly or indire...more Number of Targets: 3 |
| T3D2552 | Sticholysin 269658-04-0; 183449-91-4 | Not Available 19390.885 g/mol |  |
| Sticholysin is a cardiac stimulatory and hemolytic pore-forming protein. Pore formation likely proceeds by membrane binding via a surface rich in aromatic residues, fo...more Number of Targets: 0 |
| T3D2584 | Myotoxin (Crotalus viridis viridis) 132821-30-8 | Not Available 4827.755 g/mol |  |
| Myotoxins work by a non-enzymatic mechanism that leads to severe muscle necrosis, causing paralysis and eventually death. They may also modify voltage-sensitive sodium...more Number of Targets: 14 |
| T3D2585 | Taipoxin 52019-39-3 | Not Available 13828.660 g/mol |  |
| Taipoxin causes a gradual reduction to complete stop of evoked and spontaneous release of acetylcholine from motor nerve terminals. (L1106) Number of Targets: 0 |
| T3D2589 | Anthopleurin (Anthopleura xanthogrammica) 600880-63-9 | Not Available 5137.770 g/mol |  |
| Anthopleurin binds specifically to the voltage-gated sodium channel, thereby delaying its inactivation during signal transduction, resulting in strong stimulation of m...more Number of Targets: 14 |
| T3D2590 | Calitoxin 118354-83-9 | Not Available 8727.960 g/mol | |
| Calitoxin binds specifically to the voltage-gated sodium channel, thereby delaying its inactivation during signal transduction, resulting in strong stimulation of mamm...more Number of Targets: 14 |
| T3D2633 | Acanthophin 126601-49-8 | Not Available 8386.795 g/mol | |
| Acanthophin produces peripheral paralysis by blocking neuromuscular transmission at the postsynaptic site. It does this by binding to certain muscular and neuronal nic...more Number of Targets: 8 |
| T3D2635 | Erabutoxin 59536-69-5 | Not Available 9136.510 g/mol |  |
| Erabutoxin binds with high affinity to muscular nicotinic acetylcholine receptors (nAChRs), and with low affinity to neuronal alpha-7 nAChRs. This produces peripheral ...more Number of Targets: 6 |
| T3D2636 | Disintegrin echistatin (Echis carinatus) Not Available | Not Available 5424.090 g/mol |  |
| Disintegrins work by countering blood clotting steps, inhibiting the clumping of platelets. They inhibit fibrinogen interaction with platelet receptors expressed on gl...more Number of Targets: 2 |
| T3D2637 | Nigroxin 9001-84-7 | Not Available 13341.125 g/mol |  |
| Nigroxin is myotoxic. (T170) Number of Targets: 0 |
| T3D2638 | Notexin 37233-96-4 | Not Available 13593.310 g/mol |  |
| Notexin is myotoxic and inhibits neuromuscular transmission by blocking acetylcholine release from the nerve termini. (T170) Number of Targets: 0 |
| T3D2639 | Ohanin Not Available | Not Available 21173.945 g/mol | |
| Ohanin is extremely neurotoxic, cardiotoxic, and cytotoxic. (L1102) Number of Targets: 0 |
| T3D2640 | Pseudechetoxin Not Available | Not Available 26474.445 g/mol |  |
| Pseudechetoxin blocks olfactory and retinal cyclic nucleotide-gated (CNG) ion channel currents. It forms high-affinity contacts with the pore turret region and most li...more Number of Targets: 2 |
| T3D2642 | Viperotoxin Not Available | Not Available 15554.775 g/mol |  |
| Viperotoxin is a presynaptic neurotoxin. (T170) Number of Targets: 0 |
| T3D2643 | Vipoxin Not Available | Not Available 13827.665 g/mol |  |
| Vipoxin inhibits the binding of ligands to biogenic amine receptors including dopamine,
serotonin and alpha1/alpha2 adrenergic receptors. Vipoxin also exhibits hemoly...more Number of Targets: 28 |