You are using an unsupported browser. Please upgrade your browser to a newer version to get the best experience on Toxin, Toxin Target Database.
Filter by category:
Displaying toxins 1 - 25 of 283 in total
T3DB ID Name
CAS Number
Formula
Weight
StructureTypeMechanism of Toxicity
T3D0301Arsenobetaine
64436-13-1
C5H11AsO2
178.061 g/mol
Thumb
  • Animal Toxin
  • Arsenic Compound
  • Food Toxin
  • Metabolite
  • Natural Compound
  • Organic Compound
  • Organometallic
Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by co...more
Number of Targets: 44
T3D0302Arsenocholine
39895-81-3
C5H14AsO
165.085 g/mol
Thumb
  • Animal Toxin
  • Arsenic Compound
  • Food Toxin
  • Metabolite
  • Natural Compound
  • Organic Compound
  • Organometallic
Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by co...more
Number of Targets: 44
T3D0303Methylarsine
593-52-2
CH5As
91.972 g/mol
Thumb
  • Animal Toxin
  • Arsenic Compound
  • Natural Compound
  • Organic Compound
  • Organometallic
Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by co...more
Number of Targets: 44
T3D0304Dimethylarsine
593-57-7
C2H7As
105.999 g/mol
Thumb
  • Animal Toxin
  • Arsenic Compound
  • Natural Compound
  • Organic Compound
  • Organometallic
Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by co...more
Number of Targets: 44
T3D09033-Hydroxy-carbofuran
16655-82-6
C12H15NO4
237.252 g/mol
Thumb
  • Amine
  • Animal Toxin
  • Aromatic Hydrocarbon
  • Carbamate
  • Ester
  • Ether
  • Food Toxin
  • Metabolite
  • Natural Compound
  • Organic Compound
  • Pesticide
3-Hydroxy-carbofuran is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carbamoylation of the ac...more
Number of Targets: 2
T3D09053-Oxo-carbofuran
16709-30-1
C12H13NO4
235.236 g/mol
Thumb
  • Amine
  • Animal Toxin
  • Aromatic Hydrocarbon
  • Carbamate
  • Ester
  • Ether
  • Food Toxin
  • Metabolite
  • Natural Compound
  • Organic Compound
  • Pesticide
3-Oxo-carbofuran is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carbamoylation of the active...more
Number of Targets: 2
T3D2462Palytoxin
77734-91-9
C129H223N3O53
2664.139 g/mol
Thumb
  • Amine
  • Animal Toxin
  • Ether
  • Lachrymator
  • Marine Toxin
  • Natural Compound
  • Organic Compound
Palytoxin targets the sodium-potassium pump protein by binding to the molecule such that the molecule is locked in a position where it allows passive transport of both...more
Number of Targets: 9
T3D2463Ciguatoxin 1
11050-21-8
C60H86O19
1111.313 g/mol
Thumb
  • Animal Toxin
  • Ether
  • Food Toxin
  • Marine Toxin
  • Natural Compound
  • Organic Compound
Ciguatoxin lowers the threshold for opening voltage-gated sodium channels in synapses of the nervous system. The effect of opening a sodium channel will cause depolari...more
Number of Targets: 14
T3D2464Ciguatoxin 2
142185-85-1
C60H86O18
1095.314 g/mol
Thumb
  • Animal Toxin
  • Ether
  • Food Toxin
  • Marine Toxin
  • Natural Compound
  • Organic Compound
Ciguatoxin lowers the threshold for opening voltage-gated sodium channels in synapses of the nervous system. The effect of opening a sodium channel will cause depolari...more
Number of Targets: 14
T3D246554-Deoxyciguatoxin
139341-09-6
C60H86O18
1095.314 g/mol
Thumb
  • Animal Toxin
  • Ether
  • Food Toxin
  • Marine Toxin
  • Metabolite
  • Natural Compound
  • Organic Compound
Ciguatoxin lowers the threshold for opening voltage-gated sodium channels in synapses of the nervous system. The effect of opening a sodium channel will cause depolari...more
Number of Targets: 14
T3D2466Ciguatoxin 4B
123676-76-6
C60H84O16
1061.299 g/mol
Thumb
  • Animal Toxin
  • Ether
  • Marine Toxin
  • Natural Compound
  • Organic Compound
Ciguatoxin lowers the threshold for opening voltage-gated sodium channels in synapses of the nervous system. The effect of opening a sodium channel will cause depolari...more
Number of Targets: 14
T3D2477Insulin
11061-68-0
Not Available
11980.795 g/mol
T3d2477
  • Amide
  • Amine
  • Animal Toxin
  • Antidiabetic Agent
  • Hormone
  • Natural Compound
  • Organic Compound
  • Protein
Insulin has a direct inhibitory effect on the lipase concerned with the mobilization of fattty acids. Insulin binds to a receptor on the surface of the target cell and...more
Number of Targets: 56
T3D2484Tetrodotoxin
4368-28-9
C11H17N3O8
319.268 g/mol
Thumb
  • Amide
  • Amine
  • Animal Toxin
  • Ether
  • Marine Toxin
  • Natural Compound
  • Organic Compound
  • Sodium Channel Blocker
Tetrodotoxin binds to what is known as site 1 of the fast voltage-gated sodium channel. Site 1 is located at the extracellular pore opening of the ion channel. The bin...more
Number of Targets: 14
T3D2487Apamin (Apis mellifera)
24345-16-2
Not Available
5223.305 g/mol
T3d2487
  • Amide
  • Amine
  • Animal Toxin
  • Insect Toxin
  • Natural Compound
  • Organic Compound
  • Protein
Apamin binds to the SK channels (small conductance Ca2+-activated K+ channels) in the brain and spinal cord and inhibits them, likely by acting as a pore blocker. Inhi...more
Number of Targets: 3
T3D2489Philanthotoxin
77108-00-0
C23H41N5O3
435.603 g/mol
Thumb
  • Amide
  • Amine
  • Animal Toxin
  • Insect Toxin
  • Natural Compound
  • Organic Compound
Philanthotoxins block glutamate receptors, especially the calcium permeable AMPA receptor and kainate receptor. (L1016)
Number of Targets: 9
T3D2490alpha-Pompilidotoxin
202075-91-0
Not Available
1530.850 g/mol
T3d2490
  • Amide
  • Amine
  • Animal Toxin
  • Insect Toxin
  • Natural Compound
  • Organic Compound
  • Protein
Pompilidotoxin slows down inactivation of neuronal, but not heart sodium channels, potentiating synaptic transmission. This is believed to be done by binding to the n...more
Number of Targets: 10
T3D2491beta-Pompilidotoxin
216064-36-7
Not Available
1558.860 g/mol
T3d2491
  • Amide
  • Amine
  • Animal Toxin
  • Insect Toxin
  • Natural Compound
  • Organic Compound
  • Protein
Pompilidotoxin slows down inactivation of neuronal, but not heart sodium channels, potentiating synaptic transmission. This is believed to be done by binding to the n...more
Number of Targets: 10
T3D2492Holocyclotoxin
88254-04-0
Not Available
7834.125 g/mol
T3d2492
  • Amide
  • Amine
  • Animal Toxin
  • Insect Toxin
  • Natural Compound
  • Organic Compound
  • Protein
Holocyclotoxin produces paralysis by acting at the neuromuscular junction. (A2834)
Number of Targets: 0
T3D2493Poneratoxin
137084-94-7
Not Available
2757.330 g/mol
T3d2493
  • Amide
  • Amine
  • Animal Toxin
  • Insect Toxin
  • Natural Compound
  • Organic Compound
  • Protein
Poneratoxin affects voltage-dependent sodium ion channels and is known to block nicotinic synaptic transmission in the insect central nervous system. (L1019)
Number of Targets: 14
T3D2494omega-Agatoxin
145017-83-0
Not Available
12807.575 g/mol
T3d2494
  • Amide
  • Amine
  • Animal Toxin
  • Natural Compound
  • Organic Compound
  • Protein
  • Spider Toxin
omega-Agatoxins block the calcium channels in the presynaptic terminals of the neuromuscular junction in insects and vertebrates. This reduces calcium influx, resultin...more
Number of Targets: 1
T3D2495Atracotoxin, omega- (Hadronyche versuta)
193981-10-1
Not Available
4055.410 g/mol
T3d2495
  • Amide
  • Amine
  • Animal Toxin
  • Natural Compound
  • Organic Compound
  • Protein
  • Spider Toxin
omega-Atracotoxins inhibit invertebrate voltage-gated calcium channel currents. (T170, L1812)
Number of Targets: 0
T3D2496Versutoxin
114264-83-4
Not Available
4855.645 g/mol
T3d2496
  • Amide
  • Amine
  • Animal Toxin
  • Natural Compound
  • Organic Compound
  • Protein
  • Spider Toxin
Versutoxin inhibits both insect and mammalian voltage-gated sodium channels. It binds to site 3 in tetrodotoxin-sensitive sodium channels, which slows their inactivati...more
Number of Targets: 14
T3D2497Robustoxin
91728-12-0
Not Available
4856.685 g/mol
T3d2497
  • Amide
  • Amine
  • Animal Toxin
  • Natural Compound
  • Organic Compound
  • Protein
  • Spider Toxin
Robustoxin inhibits both insect and mammalian voltage-gated sodium channels. It binds to site 3 in tetrodotoxin-sensitive sodium channels, which slows their inactivati...more
Number of Targets: 14
T3D2498Grammotoxin
152617-90-8
Not Available
9600.980 g/mol
T3d2498
  • Amide
  • Amine
  • Animal Toxin
  • Natural Compound
  • Organic Compound
  • Protein
  • Spider Toxin
Grammotoxin inhibits P-, Q- and N-type voltage-gated calcium channels in neurons. Binding to the calcium channels modifies their voltage-dependent gating. This makes i...more
Number of Targets: 3
T3D2499Huwentoxin
526224-73-7
Not Available
9318.830 g/mol
T3d2499
  • Amide
  • Amine
  • Animal Toxin
  • Natural Compound
  • Organic Compound
  • Protein
  • Spider Toxin
Huwentoxin blocks neuromuscular transmission by binding to the nicotinic acetylcholine receptor, which affects the release of neurotransmitters from autonomic nerve en...more
Number of Targets: 17
Displaying toxins 1 - 25 of 283 in total