Browsing Toxins By Category
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D4350 | Bilirubin 635-65-4 | C33H36N4O6 584.662 g/mol |  |
| Not Available Number of Targets: 2 |
| T3D2491 | beta-Pompilidotoxin 216064-36-7 | Not Available 1558.860 g/mol |  |
| Pompilidotoxin slows down inactivation of neuronal, but not heart sodium channels, potentiating synaptic transmission. This is believed to be done by binding to the n...more Number of Targets: 10 |
| T3D2538 | beta-Bungarotoxin 12778-32-4 | Not Available 9571.020 g/mol |  |
| beta-Bungarotoxin acts at the presynaptic terminal, where it causes release of acetylcholine and subsequent exhaustion of acetylcholine stores in the nerve terminal by...more Number of Targets: 23 |
| T3D4346 | Beta-Alanine 107-95-9 | C3H7NO2 89.093 g/mol |  |
| Not Available Number of Targets: 3 |
| T3D4785 | Benzoic acid 65-85-0 | C7H6O2 122.121 g/mol |  |
| Not Available Number of Targets: 5 |
| T3D2527 | Batrachotoxin 23509-16-2 | C31H42N2O6 538.675 g/mol |  |
| Batrachotoxins act on sodium channels by modifying both their ion selectivity and voltage sensitivity. By increasing the permeability of the cell membrane, the cell is...more Number of Targets: 14 |
| T3D2672 | Azaspiracid 214899-21-5 | C47H71NO12 842.066 g/mol |  |
| Azaspiracid-4 dose-dependent inhibits the increase in cytosolic Ca2+ levels induced by thapsigargin (Tg) (A330). Azaspiracid-2 and Azaspiracid-3 clearly increase cytos...more Number of Targets: 1 |
| T3D2495 | Atracotoxin, omega- (Hadronyche versuta) 193981-10-1 | Not Available 4055.410 g/mol |  |
| omega-Atracotoxins inhibit invertebrate voltage-gated calcium channel currents. (T170, L1812) Number of Targets: 0 |
| T3D0302 | Arsenocholine 39895-81-3 | C5H14AsO 165.085 g/mol |  |
| Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by co...more Number of Targets: 44 |
| T3D0301 | Arsenobetaine 64436-13-1 | C5H11AsO2 178.061 g/mol |  |
| Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by co...more Number of Targets: 44 |
| T3D4294 | Argininosuccinic acid 2387-71-5 | C10H18N4O6 290.273 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D2532 | Arenobufagin 464-74-4 | C24H32O6 416.507 g/mol |  |
| Arenobufagin blocks the sodium/potassium pump in heart tissue. (L1078) Number of Targets: 8 |
| T3D2487 | Apamin (Apis mellifera) 24345-16-2 | Not Available 5223.305 g/mol |  |
| Apamin binds to the SK channels (small conductance Ca2+-activated K+ channels) in the brain and spinal cord and inhibits them, likely by acting as a pore blocker. Inhi...more Number of Targets: 3 |
| T3D2589 | Anthopleurin (Anthopleura xanthogrammica) 600880-63-9 | Not Available 5137.770 g/mol |  |
| Anthopleurin binds specifically to the voltage-gated sodium channel, thereby delaying its inactivation during signal transduction, resulting in strong stimulation of m...more Number of Targets: 14 |
| T3D4240 | Androstenedione 63-05-8 | C19H26O2 286.409 g/mol |  |
| Androstenedione is converted to testosterone and estrogen, and when taken in sufficient quantities androstenedione can cause unwanted masculinizing and feminizing effe...more Number of Targets: 11 |
| T3D4259 | Aminoadipic acid 542-32-5 | C6H11NO4 161.156 g/mol |  |
| Not Available Number of Targets: 4 |
| T3D4726 | Alteplase 105857-23-6 | Not Available 62916.495 g/mol |  |
| Alteplase binds to fibrin rich clots via the fibronectin finger-like domain and the Kringle 2 domain. The protease domain then cleaves the Arg/Val bond in plasminogen ...more Number of Targets: 4 |
| T3D2490 | alpha-Pompilidotoxin 202075-91-0 | Not Available 1530.850 g/mol |  |
| Pompilidotoxin slows down inactivation of neuronal, but not heart sodium channels, potentiating synaptic transmission. This is believed to be done by binding to the n...more Number of Targets: 10 |
| T3D4812 | Alpha-Linolenic Acid 463-40-1 | C18H30O2 278.430 g/mol |  |
| Alpha Linolenic Acid or ALA is considered an essential fatty acid because it is required for human health, but cannot be synthesized by humans. It is in fact a plant-...more Number of Targets: 12 |
| T3D2500 | alpha-Latrotoxin 65988-34-3 | Not Available 156855.500 g/mol |  |
| alpha-Latrotoxin acts presynaptically to release neurotransmitters from sensory and motor neurons, as well as on endocrine cells. alpha-Latrotoxin tetramers can form i...more Number of Targets: 10 |
| T3D4425 | Alpha-ketoisovaleric acid 759-05-7 | C5H8O3 116.115 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D2657 | alpha-Conotoxin (Conus geographus) Not Available | Not Available 1627.830 g/mol |  |
| alpha-Conotoxins act on postsynaptic membranes, where they inhibit nicotinic acetylcholine receptors in nerves and muscles. (L1107) Number of Targets: 15 |
| T3D2510 | alpha-Cobratoxin 769933-79-1 | Not Available 7830.960 g/mol |  |
| alpha-Cobratoxin is a muscle-type nicotinic acetylcholine receptor (nAChR) antagonist. It causes paralysis by preventing the binding of acetylcholine to the nAChR, as ...more Number of Targets: 6 |
| T3D2537 | alpha-Bungarotoxin 11032-79-4 | Not Available 10285.030 g/mol |  |
| alpha-Bungarotoxin binds irreversibly and competitively to muscular and neuronal nicotinic acetylcholine receptors. This produces peripheral paralysis by blocking neur...more Number of Targets: 8 |
| T3D2626 | alpha-Agatoxin 128549-96-2 | C26H47N7O2 489.697 g/mol |  |
| alpha-Agatoxins block the glutamate-activated receptor channels in the neuronal postsynaptic terminals of insects and mammals, preventing excitory junction potential f...more Number of Targets: 11 |