Browsing Toxins By Category
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D2523 | Scyllatoxin 142948-19-4 | Not Available 3430.130 g/mol |  |
| Scyllatoxin blocks small conductance calcium-activated potassium channels. This inhibits the slow after-hyperpolarisation that follows an action potential in some nerv...more Number of Targets: 3 |
| T3D2551 | Saxitoxin 35523-89-8 | C10H17N7O4 299.287 g/mol |  |
| Saxitoxin blocks voltage-gated sodium channels of nerve cells. (L1115) Number of Targets: 14 |
| T3D4458 | Sarcosine 107-97-1 | C3H7NO2 89.093 g/mol |  |
| Sarcosine is an oncometabolite. Sarcosine appears to upregulate the expression of the potent oncoprotein called human epidermal growth factor receptor 2 (HER2/neu) in ...more Number of Targets: 2 |
| T3D4281 | SAICAR 3031-95-6 | C13H19N4O12P 454.283 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D4398 | Saccharopine 997-68-2 | C11H20N2O6 276.286 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D4434 | S-Sulfocysteine 1637-71-4 | C3H6NO5S2 200.214 g/mol |  |
| S-Sulfocysteine (SSC) is a very potent NMDA-receptor agonist. Electrophysiological studies have shown that SSC displays depolarizing properties similar to glutamate. S...more Number of Targets: 3 |
| T3D4456 | S-Adenosylmethionine 29908-03-0 | C15H23N6O5S 399.445 g/mol |  |
| S-Adenosylmethionine (SAMe) is a natural substance present in the cells of the body. It is a direct metabolite of the essential amino acid L-methionine. SAMe plays a c...more Number of Targets: 10 |
| T3D4455 | S-Adenosylhomocysteine 979-92-0 | C14H20N6O5S 384.411 g/mol |  |
| Not Available Number of Targets: 17 |
| T3D2497 | Robustoxin 91728-12-0 | Not Available 4856.685 g/mol |  |
| Robustoxin inhibits both insect and mammalian voltage-gated sodium channels. It binds to site 3 in tetrodotoxin-sensitive sodium channels, which slows their inactivati...more Number of Targets: 14 |
| T3D2671 | Rituximab 174722-31-7 | Not Available 36105.695 g/mol |  |
| Binds to the CD20 antigen which is found on mature B lymphocytes. The Fc domain recruits immune effector functions to mediate B-cell lysis. The antibody appears to ind...more Number of Targets: 12 |
| T3D4325 | Pyruvic acid 127-17-3 | C3H4O3 88.062 g/mol |  |
| Pyruvate serves as a biological fuel by being converted to acetyl coenzyme A, which enters the tricarboxylic acid or Krebs cycle where it is metabolized to produce ATP...more Number of Targets: 16 |
| T3D4959 | Pyrophosphate 14000-31-8 | O7P2 173.946 g/mol |  |
| Not Available Number of Targets: 0 |
| T3D4270 | Pyroglutamic acid 98-79-3 | C5H7NO3 129.114 g/mol |  |
| 5-Oxoprolinuria develops in moderate to severe cases of glutathione synthetase deficiency. The deficiency in glutathione synthetase leads to the accumulation of γ-glut...more Number of Targets: 12 |
| T3D2529 | Pumiliotoxin 73376-35-9 | C16H29NO 251.408 g/mol |  |
| Pumiliotoxin affects voltage-gated calcium channels, interfering with muscle contraction in the heart and skeletal muscle. They also may block sodium and potassium cha...more Number of Targets: 25 |
| T3D2640 | Pseudechetoxin Not Available | Not Available 26474.445 g/mol |  |
| Pseudechetoxin blocks olfactory and retinal cyclic nucleotide-gated (CNG) ion channel currents. It forms high-affinity contacts with the pore turret region and most li...more Number of Targets: 2 |
| T3D4439 | Protoporphyrinogen IX 7412-77-3 | C34H40N4O4 568.706 g/mol |  |
| Not Available Number of Targets: 0 |
| T3D4440 | Protoporphyrin IX 553-12-8 | C34H34N4O4 562.658 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D4447 | Propionyl-CoA 317-66-8 | C24H40N7O17P3S 823.597 g/mol |  |
| In propionic aciduria, propionyl CoA accumulates within the mitochondria in massive quantities; free carnitine is then esterified, creating propionyl carnitine, which ...more Number of Targets: 0 |
| T3D4444 | Propionic acid 79-09-4 | C3H6O2 74.079 g/mol |  |
| In healthy individuals, the enzyme propionyl CoA carboxylase converts propionyl CoA to methylmalonyl CoA. This is one step in the process of converting certain amino a...more Number of Targets: 2 |
| T3D4344 | Potassium 7440-09-7 | K 39.098 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D4274 | Porphobilinogen 487-90-1 | C10H14N2O4 226.229 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D2493 | Poneratoxin 137084-94-7 | Not Available 2757.330 g/mol |  |
| Poneratoxin affects voltage-dependent sodium ion channels and is known to block nicotinic synaptic transmission in the insect central nervous system. (L1019) Number of Targets: 14 |
| T3D4454 | Phytanic acid 14721-66-5 | C20H40O2 312.530 g/mol |  |
| Not Available Number of Targets: 4 |
| T3D2501 | Phrixotoxin 880886-00-0 or 221872-97-5 | Not Available 3555.310 g/mol |  |
| Phrixotoxin blocks A-type potassium channels by altering the gating properties of these channels. (T170) Number of Targets: 2 |
| T3D2503 | Phoneutriatoxin Not Available | Not Available 12677.715 g/mol |  |
| Phoneutriatoxin acts as an antagonist at certain calcium channels. (T170) Number of Targets: 3 |