Browsing Toxins By Category
T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
---|---|---|---|---|---|
T3D4245 | Deoxycorticosterone 64-85-7 | C21H30O3 330.461 g/mol |
| Not Available Number of Targets: 6 | |
T3D4961 | Deoxycholic acid 83-44-3 | C24H40O4 392.572 g/mol |
| Not Available Number of Targets: 3 | |
T3D4278 | Deoxyadenosine triphosphate 1927-31-7 | C10H16N5O12P3 491.182 g/mol |
| Not Available Number of Targets: 2 | |
T3D4958 | Deoxyadenosine 958-09-8 | C10H13N5O3 251.242 g/mol |
| Not Available Number of Targets: 0 | |
T3D2545 | Dendrotoxin (Dendroaspis polylepis polylepis) 119128-61-9 | Not Available 7155.305 g/mol |
| Dendrotoxins block particular subtypes of voltage-gated potassium channels in neurons, thereby prolonging the duration of action potentials and enhancing the release o...more Number of Targets: 23 | |
T3D2546 | Dendrotoxin (Dendroaspis angusticeps) 74504-53-3 | Not Available 3417.825 g/mol |
| Dendrotoxins block particular subtypes of voltage-gated potassium channels in neurons, thereby prolonging the duration of action potentials and enhancing the release o...more Number of Targets: 23 | |
T3D2658 | delta-Conotoxin (Conus striatus) Not Available | Not Available 9216.755 g/mol |
| delta-Conotoxins inhibit the inactivation of voltage-dependent sodium channels. (L1107) Number of Targets: 14 | |
T3D4242 | Dehydroepiandrosterone sulfate 651-48-9 | C19H28O5S 368.488 g/mol |
| Although it predominantly functions as an endogenous precursor to more potent androgens such as testosterone and dihydroxytestosterone, DHEA (which is produced from DH...more Number of Targets: 0 | |
T3D4056 | Debromoaplysiatoxin 52423-28-6 | C32H48O10 592.718 g/mol |
| Debromoaplysiatoxin have the ability to evoke biological and biochemical responses in cells, and belong to the TPA (12-O-tetradecanoylphorbol 13-acetate) type tumor pr...more Number of Targets: 0 | |
T3D4307 | D-Lactic acid 10326-41-7 | C3H6O3 90.078 g/mol |
| Not Available Number of Targets: 3 | |
T3D4356 | D-Glucose 50-99-7 | C6H12O6 180.156 g/mol |
| Very high serum levels of glucose are found in untreated diabetic (type I or type II) patients. Glucose in chronic excess causes toxic effects on the structure and fun...more Number of Targets: 33 | |
T3D4345 | D-Fructose 53188-23-1 | C6H12O6 180.156 g/mol |
| Fructose is distinct from other sugars in its ability to cause intracellular ATP depletion, nucleotide turnover, and the generation of uric acid. Uric acid is generate...more Number of Targets: 5 | |
T3D4251 | D-2-Hydroxyglutaric acid 2889-31-8 | C5H8O5 148.114 g/mol |
| 2-hydroxyglutarate is an oncometabolite. It is a competitive inhibitor of multiple α-ketoglutarate-dependent dioxygenases, including histone demethylases and the TET f...more Number of Targets: 16 | |
T3D2543 | Crotoxin 9007-40-3 | Not Available 15272.965 g/mol |
| Crotoxin inhibits neuromuscular transmission by presynaptically blocking acetylcholine release from the nerve termini. (T170) Number of Targets: 0 | |
T3D2542 | Crotamine 58740-15-1 | Not Available 7518.980 g/mol |
| Crotamine specifically modifies voltage-sensitive sodium channels, it exhibits analgesic activity and causes severe muscle necrosis by a non-enzymatic mechanism. It al...more Number of Targets: 14 | |
T3D4290 | Creatine 57-00-1 | C4H9N3O2 131.133 g/mol |
| In the muscles, a fraction of the total creatine binds to phosphate - forming creatine phosphate. The reaction is catalysed by creatine kinase, and the result is phosp...more Number of Targets: 7 | |
T3D3956 | Cotinine 486-56-6 | C10H12N2O 176.215 g/mol |
| Not Available Number of Targets: 1 | |
T3D4438 | Coproporphyrinogen III 2624-63-7 | C36H44N4O8 660.757 g/mol |
| Not Available Number of Targets: 1 | |
T3D4323 | Coproporphyrin III 14643-66-4 | C36H38N4O8 654.709 g/mol |
| Not Available Number of Targets: 1 | |
T3D2544 | Convulxin 37206-04-5 | Not Available 18140.725 g/mol |
| Convulxin binds to the platelet and collagen receptor, glycoprotein VI (GPVI). This causes platelet activation in the blood forming clots and a build up of pressure, w...more Number of Targets: 1 | |
T3D2661 | Contryphan (Conus ventricosus) Not Available | Not Available 1091.260 g/mol |
| Contryphan affects both voltage-gated and calcium-dependent potassium channels. (L1108) Number of Targets: 32 | |
T3D2509 | Cobatoxin 211688-17-4 | Not Available 7131.365 g/mol |
| Cobatoxin blocks calcium-activated and voltage-gated potassium channels. (L1045) Number of Targets: 7 | |
T3D4295 | Citrulline 372-75-8 | C6H13N3O3 175.186 g/mol |
| L-citrulline is converted to L-arginine by argininosuccinate synthase. L-arginine is in turn responsible for citrulline's therapeutic affects. Many of L-arginine's act...more Number of Targets: 13 | |
T3D2535 | Cinobufagin 470-37-1 | C26H34O6 442.545 g/mol |
| Cinobufagin blocks the sodium/potassium pump in heart tissue. (L1083, L1084) Number of Targets: 0 | |
T3D2466 | Ciguatoxin 4B 123676-76-6 | C60H84O16 1061.299 g/mol |
| Ciguatoxin lowers the threshold for opening voltage-gated sodium channels in synapses of the nervous system. The effect of opening a sodium channel will cause depolari...more Number of Targets: 14 |