Browsing Toxins By Category
T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
---|---|---|---|---|---|
T3D4242 | Dehydroepiandrosterone sulfate 651-48-9 | C19H28O5S 368.488 g/mol |
| Although it predominantly functions as an endogenous precursor to more potent androgens such as testosterone and dihydroxytestosterone, DHEA (which is produced from DH...more Number of Targets: 0 | |
T3D2658 | delta-Conotoxin (Conus striatus) Not Available | Not Available 9216.755 g/mol |
| delta-Conotoxins inhibit the inactivation of voltage-dependent sodium channels. (L1107) Number of Targets: 14 | |
T3D2546 | Dendrotoxin (Dendroaspis angusticeps) 74504-53-3 | Not Available 3417.825 g/mol |
| Dendrotoxins block particular subtypes of voltage-gated potassium channels in neurons, thereby prolonging the duration of action potentials and enhancing the release o...more Number of Targets: 23 | |
T3D2545 | Dendrotoxin (Dendroaspis polylepis polylepis) 119128-61-9 | Not Available 7155.305 g/mol |
| Dendrotoxins block particular subtypes of voltage-gated potassium channels in neurons, thereby prolonging the duration of action potentials and enhancing the release o...more Number of Targets: 23 | |
T3D4958 | Deoxyadenosine 958-09-8 | C10H13N5O3 251.242 g/mol |
| Not Available Number of Targets: 0 | |
T3D4278 | Deoxyadenosine triphosphate 1927-31-7 | C10H16N5O12P3 491.182 g/mol |
| Not Available Number of Targets: 2 | |
T3D4961 | Deoxycholic acid 83-44-3 | C24H40O4 392.572 g/mol |
| Not Available Number of Targets: 3 | |
T3D4245 | Deoxycorticosterone 64-85-7 | C21H30O3 330.461 g/mol |
| Not Available Number of Targets: 6 | |
T3D4430 | Deoxyuridine triphosphate 1173-82-6 | C9H15N2O14P3 468.142 g/mol |
| Deoxyuridine triphosphate (dUTP) can be misincorporated into DNA and cause DNA damage. The extent of DNA damage caused by dUTP is dependent on the levels of the pyroph...more Number of Targets: 3 | |
T3D3241 | Diacetyl 431-03-8 | C4H6O2 86.089 g/mol |
| Diacetyl is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholinestera...more Number of Targets: 4 | |
T3D4494 | Diazoxon 962-58-3 | C12H21N2O4P 288.280 g/mol |
| Diazoxon is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholinestera...more Number of Targets: 12 | |
T3D4214 | Diethylamine 71247-25-1 | C4H11N 73.137 g/mol |
| Not Available Number of Targets: 1 | |
T3D3958 | Diethylthiophosphate 5871-17-0 | C4H11O3PS 170.167 g/mol |
| Diethylthiophosphate (DETP) induces DNA damage only in the hepatic cell lines, and this effect could be related to a secondary non-diffusible metabolite generated by t...more Number of Targets: 1 | |
T3D4751 | Dihydrotestosterone 521-18-6 | C19H30O2 290.440 g/mol |
| Not Available Number of Targets: 7 | |
T3D4332 | Dihydrothymine 696-04-8 | C5H8N2O2 128.129 g/mol |
| Dihydropyrimidine dehydrogenase catalyzes the reduction of thymine to 5, 6-dihydrothymine then dihydropyrimidinase hydrolyzes 5, 6-dihydrothymine to N-carbamyl-b-alani...more Number of Targets: 0 | |
T3D4333 | Dihydrouracil 504-07-4 | C4H6N2O2 114.103 g/mol |
| Not Available Number of Targets: 0 | |
T3D0304 | Dimethylarsine 593-57-7 | C2H7As 105.999 g/mol |
| Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by co...more Number of Targets: 44 | |
T3D4030 | Dinophysistoxin 1 81720-10-7 | C45H70O13 819.030 g/mol |
| Dinophysistoxin 1 (DTX1) is the analogue of okadaic acid causing diarrheic shellfish poisoning (DSP) in humans shortly after the ingestion of contaminated seafood. DTX...more Number of Targets: 0 | |
T3D2636 | Disintegrin echistatin (Echis carinatus) Not Available | Not Available 5424.090 g/mol |
| Disintegrins work by countering blood clotting steps, inhibiting the clumping of platelets. They inhibit fibrinogen interaction with platelet receptors expressed on gl...more Number of Targets: 2 | |
T3D4040 | Domoic acid 14277-97-5 | C15H21NO6 311.330 g/mol |
| Domoic acid acts as a neurotoxin. It induces excitotoxicity by an integrative action on ionotropic glutamate receptors at both sides of the synapse for which it has hi...more Number of Targets: 1 | |
T3D4300 | Dopamine 51-61-6 | C8H11NO2 153.178 g/mol |
| Dopamine is a precursor to norepinephrine in noradrenergic nerves and is also a neurotransmitter in certain areas of the central nervous system. Dopamine produces posi...more Number of Targets: 15 | |
T3D2549 | Eledoisin (Eledone cirrhosa) 69-25-0 | Not Available 1206.410 g/mol |
| Eledoisin is a tachykinin peptide. Tachykinins excite neurons, evoke behavioural responses, are potent vasodilators and secretagogues, and contract (directly or indire...more Number of Targets: 3 | |
T3D3967 | Enterolactone 76543-15-2 | C18H18O4 298.333 g/mol |
| Not Available Number of Targets: 3 | |
T3D2530 | Epibatidine 140111-52-0 | C11H13ClN2 208.687 g/mol |
| Epibatidine works by binding and activating nicotinic acetylcholine receptors. (L1074) Number of Targets: 17 | |
T3D3962 | Equol 531-95-3 | C15H14O3 242.270 g/mol |
| Not Available Number of Targets: 2 |