Browsing Toxins By Category
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D4242 | Dehydroepiandrosterone sulfate 651-48-9 | C19H28O5S 368.488 g/mol |  |
| Although it predominantly functions as an endogenous precursor to more potent androgens such as testosterone and dihydroxytestosterone, DHEA (which is produced from DH...more Number of Targets: 0 |
| T3D4284 | 18-Hydroxycorticosterone 561-65-9 | C21H30O5 362.460 g/mol |  |
| 18-Hydroxycorticosterone is a derivative of corticosterone. It serves as an intermediate in the synthesis of aldosterone by the enzyme aldosterone synthase in the zona...more Number of Targets: 1 |
| T3D4804 | 2,4,6-Tribromophenol 118-79-6 | C6H3Br3O 330.799 g/mol |  |
| Not Available Number of Targets: 3 |
| T3D4245 | Deoxycorticosterone 64-85-7 | C21H30O3 330.461 g/mol |  |
| Not Available Number of Targets: 6 |
| T3D4282 | 17-Hydroxyprogesterone 68-96-2 | C21H30O3 330.461 g/mol |  |
| Not Available Number of Targets: 8 |
| T3D2484 | Tetrodotoxin 4368-28-9 | C11H17N3O8 319.268 g/mol |  |
| Tetrodotoxin binds to what is known as site 1 of the fast voltage-gated sodium channel. Site 1 is located at the extracellular pore opening of the ion channel. The bin...more Number of Targets: 14 |
| T3D4023 | Neosaxitoxin 64296-20-4 | C10H17N7O5 315.286 g/mol |  |
| Neosaxitoxin (NSTX) blocks the extracellular portion, the outer vestibule, of some voltage gated sodium channels in a very powerful and reversible manner, without affe...more Number of Targets: 0 |
| T3D4519 | Malaoxon 1634-78-2 | C10H19O7PS 314.292 g/mol |  |
| Malaoxon is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholinestera...more Number of Targets: 9 |
| T3D4454 | Phytanic acid 14721-66-5 | C20H40O2 312.530 g/mol |  |
| Not Available Number of Targets: 4 |
| T3D4040 | Domoic acid 14277-97-5 | C15H21NO6 311.330 g/mol |  |
| Domoic acid acts as a neurotoxin. It induces excitotoxicity by an integrative action on ionotropic glutamate receptors at both sides of the synapse for which it has hi...more Number of Targets: 1 |
| T3D4352 | Glutathione 70-18-8 | C10H17N3O6S 307.323 g/mol |  |
| Glutathione (GSH) participates in leukotriene synthesis and is a cofactor for the enzyme glutathione peroxidase. It is also important as a hydrophilic molecule that is...more Number of Targets: 42 |
| T3D2551 | Saxitoxin 35523-89-8 | C10H17N7O4 299.287 g/mol |  |
| Saxitoxin blocks voltage-gated sodium channels of nerve cells. (L1115) Number of Targets: 14 |
| T3D3967 | Enterolactone 76543-15-2 | C18H18O4 298.333 g/mol |  |
| Not Available Number of Targets: 3 |
| T3D4993 | 2-hydroxyflutamide 52806-53-8 | C11H11F3N2O4 292.211 g/mol |  |
| Hydroxyflutamide is an antiandrogen. Antiandrogens alter the androgen pathway by blocking the appropriate receptors, competing for binding sites on the cell's surface,...more Number of Targets: 0 |
| T3D4372 | Hawkinsin 63224-90-8 | C11H17NO6S 291.321 g/mol |  |
| Not Available Number of Targets: 0 |
| T3D4751 | Dihydrotestosterone 521-18-6 | C19H30O2 290.440 g/mol |  |
| Not Available Number of Targets: 7 |
| T3D4294 | Argininosuccinic acid 2387-71-5 | C10H18N4O6 290.273 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D4283 | Testosterone 58-22-0 | C19H28O2 288.424 g/mol |  |
| Testosterone is considered an anabolic steroid. It plays a key role in the development of male reproductive tissues such as the testis and prostate as well as promotin...more Number of Targets: 10 |
| T3D4790 | Estriol 50-27-1 | C18H24O3 288.381 g/mol |  |
| Estriol levels can be measured to give an indication of the general health of the fetus. DHEA-S is produced by the adrenal cortex of the fetus. This is converted to es...more Number of Targets: 4 |
| T3D4494 | Diazoxon 962-58-3 | C12H21N2O4P 288.280 g/mol |  |
| Diazoxon is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholinestera...more Number of Targets: 12 |
| T3D4240 | Androstenedione 63-05-8 | C19H26O2 286.409 g/mol |  |
| Androstenedione is converted to testosterone and estrogen, and when taken in sufficient quantities androstenedione can cause unwanted masculinizing and feminizing effe...more Number of Targets: 11 |
| T3D4990 | 2,2,4-Trimethyl-1,3-pentadienol diisobutyrate 6846-50-0 | C16H30O4 286.407 g/mol |  |
| Not Available Number of Targets: 0 |
| T3D4755 | Stearic acid 57-11-4 | C18H36O2 284.477 g/mol |  |
| Not Available Number of Targets: 7 |
| T3D2528 | Histrionicotoxin 34272-51-0 | C19H25NO 283.408 g/mol |  |
| Histrionicotoxin is a potent non-competitive antagonist of nicotinic acetylcholine receptors. (L1072) Number of Targets: 16 |
| T3D4802 | Oleic acid 112-80-1 | C18H34O2 282.461 g/mol |  |
| Not Available Number of Targets: 5 |