Browsing Toxins By Category
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D2589 | Anthopleurin (Anthopleura xanthogrammica) 600880-63-9 | Not Available 5137.770 g/mol |  |
| Anthopleurin binds specifically to the voltage-gated sodium channel, thereby delaying its inactivation during signal transduction, resulting in strong stimulation of m...more Number of Targets: 14 |
| T3D2587 | Maitotoxin 59392-53-9 | C164H256Na2O68S2 3425.856 g/mol |  |
| Maitotoxin activates calcium permeable, non-selective cation channels, leading to an increase in levels of cytosolic calcium ions. It is thought that maitotoxin leads ...more Number of Targets: 0 |
| T3D2585 | Taipoxin 52019-39-3 | Not Available 13828.660 g/mol |  |
| Taipoxin causes a gradual reduction to complete stop of evoked and spontaneous release of acetylcholine from motor nerve terminals. (L1106) Number of Targets: 0 |
| T3D2584 | Myotoxin (Crotalus viridis viridis) 132821-30-8 | Not Available 4827.755 g/mol |  |
| Myotoxins work by a non-enzymatic mechanism that leads to severe muscle necrosis, causing paralysis and eventually death. They may also modify voltage-sensitive sodium...more Number of Targets: 14 |
| T3D2582 | Maurocalcin 269745-22-4 | Not Available 3864.570 g/mol |  |
| Maurocalcin potently and reversibly modifies channel gating behaviour of the type 1 ryanodine receptor by inducing prominent subconductance behaviour. (T170) Number of Targets: 1 |
| T3D2581 | Hongotoxin 203526-59-4 | Not Available 4226.080 g/mol |  |
| Hongotoxin inhibits voltage-gated potassium channels. (L1049) Number of Targets: 4 |
| T3D2580 | Mastoparan (Vespa tropica) 72093-21-1 | Not Available 1625.055 g/mol |  |
| Mastoparan causes varying types of exocytosis, depending on its location. In mast cells it causes histamine secretion, while in platelets and chromaffin cells the rele...more Number of Targets: 0 |
| T3D2566 | Heparin 9005-49-6 | C26H41NO34S4 1039.850 g/mol |  |
| Heparin-induced thrombocytopenia (HIT) is caused by the formation of abnormal antibodies that activate platelets. Heparin occurs naturally in the human body, but the d...more Number of Targets: 14 |
| T3D2552 | Sticholysin 269658-04-0; 183449-91-4 | Not Available 19390.885 g/mol |  |
| Sticholysin is a cardiac stimulatory and hemolytic pore-forming protein. Pore formation likely proceeds by membrane binding via a surface rich in aromatic residues, fo...more Number of Targets: 0 |
| T3D2551 | Saxitoxin 35523-89-8 | C10H17N7O4 299.287 g/mol |  |
| Saxitoxin blocks voltage-gated sodium channels of nerve cells. (L1115) Number of Targets: 14 |
| T3D2550 | Onchidal 67656-42-2 | C17H24O3 276.371 g/mol |  |
| Onchidal is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholinestera...more Number of Targets: 1 |
| T3D2549 | Eledoisin (Eledone cirrhosa) 69-25-0 | Not Available 1206.410 g/mol |  |
| Eledoisin is a tachykinin peptide. Tachykinins excite neurons, evoke behavioural responses, are potent vasodilators and secretagogues, and contract (directly or indire...more Number of Targets: 3 |
| T3D2547 | Taicatoxin 112154-17-3 | Not Available 9711.255 g/mol |  |
| Taicatoxin blocks the voltage-dependent L-type calcium channels from the heart and on the small conductance calcium-activated potassium channels in the brain. (L1105) Number of Targets: 11 |
| T3D2546 | Dendrotoxin (Dendroaspis angusticeps) 74504-53-3 | Not Available 3417.825 g/mol |  |
| Dendrotoxins block particular subtypes of voltage-gated potassium channels in neurons, thereby prolonging the duration of action potentials and enhancing the release o...more Number of Targets: 23 |
| T3D2545 | Dendrotoxin (Dendroaspis polylepis polylepis) 119128-61-9 | Not Available 7155.305 g/mol |  |
| Dendrotoxins block particular subtypes of voltage-gated potassium channels in neurons, thereby prolonging the duration of action potentials and enhancing the release o...more Number of Targets: 23 |
| T3D2544 | Convulxin 37206-04-5 | Not Available 18140.725 g/mol |  |
| Convulxin binds to the platelet and collagen receptor, glycoprotein VI (GPVI). This causes platelet activation in the blood forming clots and a build up of pressure, w...more Number of Targets: 1 |
| T3D2543 | Crotoxin 9007-40-3 | Not Available 15272.965 g/mol |  |
| Crotoxin inhibits neuromuscular transmission by presynaptically blocking acetylcholine release from the nerve termini. (T170) Number of Targets: 0 |
| T3D2542 | Crotamine 58740-15-1 | Not Available 7518.980 g/mol |  |
| Crotamine specifically modifies voltage-sensitive sodium channels, it exhibits analgesic activity and causes severe muscle necrosis by a non-enzymatic mechanism. It al...more Number of Targets: 14 |
| T3D2541 | Cardiotoxin (Naja atra) 155808-00-7 | Not Available 8991.970 g/mol |  |
| Cardiotoxin binds to the cell membrane and depolarizes cardiomyocytes. It also shows lytic activities on many other cells, including red blood cells. It also targets t...more Number of Targets: 11 |
| T3D2540 | Calcicludine 178037-96-2 | Not Available 6986.205 g/mol |  |
| Calcicludine inhibits high-voltage-activated calcium channels, especially of the L-type. (L1092) Number of Targets: 10 |
| T3D2539 | Calciseptine 134710-25-1 | Not Available 7044.155 g/mol |  |
| Calciseptine is a specific blocker of the L-type calcium channel, and as a result also a smooth muscle relaxant and an inhibitor of cardiac contractions. (T170) Number of Targets: 8 |
| T3D2538 | beta-Bungarotoxin 12778-32-4 | Not Available 9571.020 g/mol |  |
| beta-Bungarotoxin acts at the presynaptic terminal, where it causes release of acetylcholine and subsequent exhaustion of acetylcholine stores in the nerve terminal by...more Number of Targets: 23 |
| T3D2537 | alpha-Bungarotoxin 11032-79-4 | Not Available 10285.030 g/mol |  |
| alpha-Bungarotoxin binds irreversibly and competitively to muscular and neuronal nicotinic acetylcholine receptors. This produces peripheral paralysis by blocking neur...more Number of Targets: 8 |
| T3D2536 | Marinobufagenin 470-42-8 | C24H32O5 400.508 g/mol |  |
| Marinobufagin blocks the sodium/potassium pump in heart tissue. (L1084, L1085) Number of Targets: 0 |
| T3D2535 | Cinobufagin 470-37-1 | C26H34O6 442.545 g/mol |  |
| Cinobufagin blocks the sodium/potassium pump in heart tissue. (L1083, L1084) Number of Targets: 0 |